scholarly journals Corrigendum: A Dual-Color Far-Red to Near-Infrared Firefly Luciferin Analogue Designed for Multiparametric Bioluminescence Imaging

2015 ◽  
Vol 54 (6) ◽  
pp. 1698-1698 ◽  
Author(s):  
Amit P. Jathoul ◽  
Helen Grounds ◽  
James C. Anderson ◽  
Martin A. Pule
2015 ◽  
Vol 127 (6) ◽  
pp. 1718-1718
Author(s):  
Amit P. Jathoul ◽  
Helen Grounds ◽  
James C. Anderson ◽  
Martin A. Pule

2014 ◽  
Vol 126 (48) ◽  
pp. 13275-13279 ◽  
Author(s):  
Amit P. Jathoul ◽  
Helen Grounds ◽  
James C. Anderson ◽  
Martin A. Pule

2014 ◽  
Vol 53 (48) ◽  
pp. 13059-13063 ◽  
Author(s):  
Amit P. Jathoul ◽  
Helen Grounds ◽  
James C. Anderson ◽  
Martin A. Pule

2021 ◽  
Vol 2 (3) ◽  
pp. 100662
Author(s):  
Giorgia Zambito ◽  
Laura Mezzanotte

ChemBioChem ◽  
2019 ◽  
Vol 20 (15) ◽  
pp. 1919-1923 ◽  
Author(s):  
Masahiro Abe ◽  
Ryo Nishihara ◽  
Yuma Ikeda ◽  
Takahiro Nakajima ◽  
Moritoshi Sato ◽  
...  

PLoS ONE ◽  
2011 ◽  
Vol 6 (4) ◽  
pp. e19277 ◽  
Author(s):  
Laura Mezzanotte ◽  
Ivo Que ◽  
Eric Kaijzel ◽  
Bruce Branchini ◽  
Aldo Roda ◽  
...  

Chirality ◽  
2020 ◽  
Vol 32 (7) ◽  
pp. 922-931 ◽  
Author(s):  
Nobuo Kitada ◽  
Ryohei Saito ◽  
Rika Obata ◽  
Satoshi Iwano ◽  
Kazuma Karube ◽  
...  

2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Mamoru Fukuchi ◽  
Ryohei Saito ◽  
Shojiro Maki ◽  
Nami Hagiwara ◽  
Yumena Nakajima ◽  
...  

Abstract Altered levels of brain-derived neurotrophic factor (BDNF) have been reported in neurologically diseased human brains. Therefore, it is important to understand how the expression of BDNF is controlled under pathophysiological as well as physiological conditions. Here, we report a method to visualize changes in BDNF expression in the living mouse brain using bioluminescence imaging (BLI). We previously generated a novel transgenic mouse strain, Bdnf-Luciferase (Luc), to monitor changes in Bdnf expression; however, it was difficult to detect brain-derived signals in the strain using BLI with d-luciferin, probably because of incomplete substrate distribution and light penetration. We demonstrate that TokeOni, which uniformly distributes throughout the whole mouse body after systematic injection and produces a near-infrared bioluminescence light, was suitable for detecting signals from the brain of the Bdnf-Luc mouse. We clearly detected brain-derived bioluminescence signals that crossed the skin and skull after intraperitoneal injection of TokeOni. However, repeated BLI using TokeOni should be limited, because repeated injection of TokeOni on the same day reduced the bioluminescence signal, presumably by product inhibition. We successfully visualized kainic acid-induced Bdnf expression in the hippocampus and sensory stimulation-induced Bdnf expression in the visual cortex. Taken together, non-invasive near-infrared BLI using Bdnf-Luc mice with TokeOni allowed us to evaluate alterations in BDNF levels in the living mouse brain. This will enable better understanding of the involvement of BDNF expression in the pathogenesis and pathophysiology of neurological diseases.


Tetrahedron ◽  
2018 ◽  
Vol 74 (6) ◽  
pp. 652-660 ◽  
Author(s):  
Masahiro Kiyama ◽  
Satoshi Iwano ◽  
Satoshi Otsuka ◽  
Shijia W. Lu ◽  
Rika Obata ◽  
...  

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