Transition metal organometallics for organic synthesis, F J McQuillin, D J Parker and G R Stephenson, Cambridge University Press, Cambridge, 1992, £100 in hardback, $200, ISBN 0 521 33353 9

1993 ◽  
Vol 7 (3) ◽  
pp. 224-224 ◽  
Author(s):  
P J Craig
2018 ◽  
Vol 15 (7) ◽  
pp. 940-971 ◽  
Author(s):  
Navjeet Kaur

Background: Due to significant biological activity associated with N-, O- and S-heterocycles, a number of reports for their synthesis have appeared in recent decades. Traditional approaches require expensive or highly specialized equipment or would be of limited use to the synthetic organic chemist due to their highly inconvenient approaches. This review summarizes the applications of copper catalysts with the emphasis on their synthetic applications for nitrogen bearing polyheterocylces. In summary, this review article describes the synthesis of a number of five-membered poly heterocyclic rings. Objective: Nowadays new approaches that employ atom-economical and efficient pathway have been developed. The researchers are following natural models to design and synthesize heterocycles. The transition metal catalyzed protocols have attracted the attention as compared to other synthetic methodologies because they use easily available substrates to build multiple substituted complicated molecules directly under mild conditions. In organic synthesis, constituted by transition metal catalyzed coupling transformations are one of the most powerful and useful protocols. The N-heterocycles are synthesized by this convenient and useful tool. Conclusion: The efficient and chemoselective synthesis of heterocycles by this technique has appeared as an important tool. This review shows a highly dynamic research field and the employment of copper catalysts in organic synthesis. Several strategies have been pointed out in the past few years, to meet more sustainable, efficient and environmentally benign chemical products and procedures. The catalytic strategies have been the focus of intense research because they avoid the use of toxic reagents. Among these catalytic strategies, highly rewarding and an important method in heterocycles synthesis is metal catalyzed synthesis.


2021 ◽  
Author(s):  
Sujoy Rana ◽  
Jyoti Prasad Biswas ◽  
Sabarni Paul ◽  
Aniruddha Paik ◽  
Debabrata Maiti

The promising aspects of iron in synthetic chemistry are being explored for three-four decades as a green and eco-friendly alternative to late transition metals. This present review unveils these rich iron-chemistry towards different transformations.


Author(s):  
Ke-Yin Ye ◽  
Jun-Song Zhong ◽  
Yi Yu ◽  
Zhaojiang Shi

The merger of transition-metal catalysis and electrochemistry has been emerging as a very versatile and robust synthetic tool in organic synthesis. Like in their non-electrochemical variants, ligands also play crucial...


1971 ◽  
Vol 17 ◽  
pp. 303-326 ◽  

Edward Armand Guggenheim was born on 11 August 1901 in Manchester; he was the elder brother of a family of three. His father, Armand Guggenheim, was of Swiss nationality but became a naturalized British subject at the age of forty-six in 1906. He was the senior partner in E. Spinner & Co., importers of Indian cotton and exporters of cotton cloth, especially khaki, and during the years 1917-1923 was also the Swiss Consul in Manchester. Edward after attending Terra Nova School, Birkdale, Southport, proceeded at the age of fourteen with a Junior Scholarship to Charterhouse. At first he was on the classical side but he switched to the science side where he came under the influence of two outstanding mathematics teachers, C. O. Tuckey and Alfred Lodge who was the brother of the more famous Oliver Lodge. His high intellectual qualities developed rapidly at Charterhouse, where he gained a Senior Scholarship in 1917 and was top of the sixth form in mathematical sciences for the period 1918-1920. His strong character and desire for authority were recognized by his election to the Head of House during his last year at School. Edward’s father died at the early age of 63, but his mother lived much longer and was an admirable hostess to Edward’s friends. After declining an Exhibition in the previous year, Edward won a Scholarship from Charterhouse to Cambridge University at Gonville and Caius College in 1920. One year later he obtained a first-class mathematical tripos in Part 1 and in 1923 a first-class in the natural science tripos, Part 2, in chemistry. One imagines that his theoretical papers were outstanding, since his practical ability at that time appears not to have been exceptionally high, particularly in preparative organic chemistry. After completion of an organic synthesis, which should have given a crystalline product, he was holding a test-tube containing a small volume of a viscous tarry material. It is reported that he contrived to collide with a perambulating demonstrator and, with studied carelessness, allowed the only record of his work to slip through his fingers with consequent breakage of the test-tube.


2019 ◽  
Vol 91 (1) ◽  
pp. 87-94 ◽  
Author(s):  
Wei Ren ◽  
Qiang Yang ◽  
Shang-Dong Yang

Abstract Phosphorus-radical participated difunctionalization reactions with unsaturated compounds have been recognized as powerful method for organic synthesis. This review covers our recent work on the application of transition metal catalyzed P-radical promoted difunctionalization for synthesis of organophosphorus compounds.


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