Swelling kinetics of modified poly(vinyl alcohol) hydrogels

2003 ◽  
Vol 90 (12) ◽  
pp. 3310-3313 ◽  
Author(s):  
Seon Jeong Kim ◽  
Ki Jung Lee ◽  
In Young Kim ◽  
Young Moo Lee ◽  
Sun I. Kim



2003 ◽  
Vol 40 (5) ◽  
pp. 501-510 ◽  
Author(s):  
Seon Jeong Kim ◽  
Ki Jung Lee ◽  
In Young Kim ◽  
Sun I. Kim


2014 ◽  
Vol 36 (1) ◽  
pp. 34-41 ◽  
Author(s):  
Monalisha Boruah ◽  
Medha Mili ◽  
Shyamalima Sharma ◽  
Biswajit Gogoi ◽  
Swapan Kumar Dolui


1982 ◽  
Vol 27 (12) ◽  
pp. 4787-4797 ◽  
Author(s):  
Nikolaos A. Peppas ◽  
Paula J. Hansen


1996 ◽  
Vol 105 (10) ◽  
pp. 4350-4357 ◽  
Author(s):  
Mitsuhiro Shibayama ◽  
Masao Uesaka ◽  
Yasuhiro Shiwa


2015 ◽  
Vol 1095 ◽  
pp. 423-426
Author(s):  
Mian Mian Zhang ◽  
Yu Xi Chen ◽  
Xia Ma

In this article, the swelling behavior and swelling kinetic of poly (vinyl alcohol)/poly (γ-glutamic acid) hydrogel were investigated. It was found that the PGA/PVA hydrogels revealed the pH-sensitive property and exhibited a faster swelling at pH7.4. The study of swelling kinetics revealed that the swelling mechanism followed the non-Fickian diffusion mechanism.



Materials ◽  
2019 ◽  
Vol 12 (19) ◽  
pp. 3220
Author(s):  
Iuliana Samoila ◽  
Sorina Dinescu ◽  
Gratiela Gradisteanu Pircalabioru ◽  
Luminita Marutescu ◽  
Gheorghe Fundueanu ◽  
...  

Composite hydrogels based on pullulan (HP) and poly(vinyl alcohol) (PVA) were both prepared by simple chemical crosslinking with sodium trimethaphosphate (STMP) or by dual crosslinking (simultaneously chemical crosslinking with STMP and physical crosslinking by freeze-thaw technique). The resulting hydrogels and cryogels were designed for tissue engineering applications. PVA, with two different molecular weights (47,000 and 125,000 g/mol; PVA47 and PVA125, respectively), as well as different P/PVA weight ratios were tested. The physico-chemical characterization of the hydrogels was performed by FTIR spectroscopy and scanning electron microscopy (SEM). The swelling kinetics, dissolution behavior, and degradation profiles in simulated physiological conditions (phosphate buffer at pH 7.4) were investigated. Pullulan concentration and the crosslinking method had significant effects on the pore size, swelling ratio, and degradation profiles. Cryogels exhibit lower swelling capacities than the conventional hydrogels but have better stability against hydrolitic degradation. Biocompatibility of the hydrogels was also investigated by both MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and LDH (lactaten dehydrogenase) assay. The MTT and LDH assays proved that dual crosslinked HP/PVA125 (75:25, w/w) scaffolds are more biocompatible and promote to a greater extent the adhesion and proliferation of L929 murine fibroblast cells than chemically crosslinked HP/PVA47 (50/50, w/w) scaffolds. Moreover, the HP/PVA125 cryogel had the best ability for the adipogenic differentiation of cells. The overall results demonstrated that the HP/PVA composite hydrogels or cryogels are suitable biomaterials for tissue engineering applications.



Polymer ◽  
1991 ◽  
Vol 32 (17) ◽  
pp. 3177-3181 ◽  
Author(s):  
Chien-Lang Ku ◽  
Jyh-Horung Chen ◽  
Lian-Pin Hwang


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