Lewis acid–base property of P(VDF-co-HFP) measured by inverse gas chromatography

2007 ◽  
Vol 107 (3) ◽  
pp. 1642-1646 ◽  
Author(s):  
Baoli Shi ◽  
Mingjia He
Keyword(s):  
Gas Chromatography ◽  
Lewis Acid ◽  
Inverse Gas Chromatography ◽  
Acid Base ◽  
Base Property ◽  
Acid Base Property

Surface Lewis acid–base properties of polymers measured by inverse gas chromatography

2007 ◽  
Vol 1149 (2) ◽  
pp. 390-393 ◽  
Author(s):  
Baoli Shi ◽  
Qianru Zhang ◽  
Lina Jia ◽  
Yang Liu ◽  
Bin Li
Keyword(s):  
Gas Chromatography ◽  
Lewis Acid ◽  
Inverse Gas Chromatography ◽  
Acid Base ◽  
Base Properties

scholarly journals Surface Characterization of Phenylpropanolamine Drug by Inverse Gas Chromatography

2013 ◽  
Vol 2013 ◽  
pp. 1-5
Author(s):  
B. Praveen Kumar ◽  
P. Reddi Rani ◽  
T. Madhusudana Reddy ◽  
K. S. Reddy
Keyword(s):  
Gas Chromatography ◽  
Lewis Acid ◽  
Surface Characterization ◽  
Inverse Gas Chromatography ◽  
Retention Data ◽  
Acid Base ◽  
Release Process ◽  
Enthalpy Of Adsorption ◽  
Base Parameters ◽  
Polar Solutes

The surface thermodynamic properties can be used to understand the interactive potential of a drug surface with a solid or liquid excipient during its formulation and drug release process. The retention data were measured for n-alkanes and polar solutes at intervals of 5 K in the temperature range 318.15–333.15 K by Inverse Gas Chromatography (IGC) on the solid surface of phenylpropanolamine (PPA) drug. The retention data were used to evaluate the dispersive surface free energy, γSd, and Lewis acid-base parameters, Ka and Kb, for the PPA drug. The values, γSd, were decreasing linearly with increase of temperature and at 323.15 K the value was found to be 26.01±0.40 mJ/m2. The specific components of enthalpy of adsorption of polar solutes have been applied to evaluate Lewis acid-base parameters. The Ka and Kb values were found to be 0.451±0.033  and 0.824±0.622, respectively, which suggests that the PPA surface contains more basic sites and interact strongly in the acidic environment.

Sign in / Sign up

Export Citation Format

Share Document