scholarly journals Increased expression of the Akt/PKB inhibitor TRB3 in osteoarthritic chondrocytes inhibits insulin-like growth factor 1-mediated cell survival and proteoglycan synthesis

2009 ◽  
Vol 60 (2) ◽  
pp. 492-500 ◽  
Author(s):  
John D. Cravero ◽  
Cathy S. Carlson ◽  
Hee-Jeong Im ◽  
Raghunatha R. Yammani ◽  
David Long ◽  
...  
Keyword(s):  
Growth Factor ◽  
Cell Survival ◽  
Proteoglycan Synthesis ◽  
Insulin Like Growth Factor ◽  
Osteoarthritic Chondrocytes

Mechanisms of Age-Related Decline in Insulin-Like Growth Factor-I Dependent Proteoglycan Synthesis in Rat Intervertebral Disc Cells

Spine ◽  
2001 ◽  
Vol 26 (22) ◽  
pp. 2421-2426 ◽  
Author(s):  
Shin’ya Okuda ◽  
Akira Myoui ◽  
Kenta Ariga ◽  
Takanobu Nakase ◽  
Kazuo Yonenobu ◽  
...  
Keyword(s):  
Growth Factor ◽  
Intervertebral Disc ◽  
Proteoglycan Synthesis ◽  
Insulin Like Growth Factor ◽  
Factor I ◽  
Age Related ◽  
Disc Cells ◽  
Growth Factor I

scholarly journals Adenovirus-mediated gene transfer of insulin-like growth factor 1 stimulates proteoglycan synthesis in rabbit joints

2000 ◽  
Vol 43 (11) ◽  
pp. 2563-2570 ◽  
Author(s):  
Zhibao Mi ◽  
Steven C. Ghivizzani ◽  
Eric R. Lechman ◽  
Daniel Jaffurs ◽  
Joseph C. Glorioso ◽  
...  
Keyword(s):  
Growth Factor ◽  
Gene Transfer ◽  
Proteoglycan Synthesis ◽  
Insulin Like Growth Factor

scholarly journals LOCALIZATION OF INSULIN-LIKE GROWTH FACTOR-1 RECEPTOR IN HUMAN NORMAL AND OSTEOARTHRITIC CARTILAGE IN RELATION TO PROTEOGLYCAN SYNTHESIS AND CONTENT

Rheumatology ◽  
1995 ◽  
Vol 35 (11) ◽  
pp. 1044-1055 ◽  
Author(s):  
P. J. VERSCHURE ◽  
J. VAN MARLE ◽  
L. A. B. JOOSTEN ◽  
M. M. A. HELSEN ◽  
F. P. J. G. LAFEBER ◽  
...  
Keyword(s):  
Growth Factor ◽  
Proteoglycan Synthesis ◽  
Insulin Like Growth Factor ◽  
Osteoarthritic Cartilage
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