Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma

Dermal Fibrosis ◽

Genetic Deletion

A transgenic mouse model for the in vivo bioluminescence imaging of the expression of the lysophosphatidic acid receptor 3: relevance for inflammation and uterine physiology research

Transgenic Research ◽

10.1007/s11248-015-9882-8 ◽

2015 ◽

Vol 24 (4) ◽

pp. 625-634 ◽

Cited By ~ 2

Author(s):

Chenqi Zhao ◽

Anne Sardella ◽

Lynn Davis ◽

Patrice E. Poubelle ◽

Sylvain G. Bourgoin ◽

...

Keyword(s):

Mouse Model ◽

Transgenic Mouse ◽

Lysophosphatidic Acid ◽

Bioluminescence Imaging ◽

Transgenic Mouse Model ◽

Acid Receptor ◽

In Vivo Bioluminescence Imaging

Lysophosphatidic acid receptor 1 antagonist ki16425 blunts abdominal and systemic inflammation in a mouse model of peritoneal sepsis

Translational Research ◽

10.1016/j.trsl.2015.01.008 ◽

2015 ◽

Vol 166 (1) ◽

pp. 80-88 ◽

Cited By ~ 15

Author(s):

Jing Zhao ◽

Jianxin Wei ◽

Nathaniel Weathington ◽

Anastasia M. Jacko ◽

Hai Huang ◽

...

Keyword(s):

Mouse Model ◽

Systemic Inflammation ◽

Lysophosphatidic Acid ◽

Acid Receptor ◽

The Effect of ASP6432, a Novel Type 1 Lysophosphatidic Acid Receptor Antagonist, on Urethral Function and Prostate Cell Proliferation

10.26226/morressier.59b63e3fd462b8029238929e ◽

2017 ◽

Author(s):

Kazuyuki Sakamoto

Keyword(s):

Cell Proliferation ◽

Receptor Antagonist ◽

Lysophosphatidic Acid ◽

Prostate Cell ◽

Acid Receptor ◽

Urethral Function

Faculty Opinions recommendation of The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1103139.559129 ◽

2008 ◽

Author(s):

Michael Pillinger

Keyword(s):

Pulmonary Fibrosis ◽

Lung Injury ◽

Lysophosphatidic Acid ◽

Vascular Leak ◽

Acid Receptor ◽

Interaction of the SARS-COV2 Envelope Protein (E) with Lysophosphatidic Acid Receptor 1 (LPAR1) and Additional Human Proteins Involved in Inflammation, Immunity, ADP Ribosylation and Vesicular Transport

SSRN Electronic Journal ◽

10.2139/ssrn.3701791 ◽

2020 ◽

Author(s):

Girish Nallur

Keyword(s):

Lysophosphatidic Acid ◽

Envelope Protein ◽

Vesicular Transport ◽

Acid Receptor ◽

Adp Ribosylation ◽

Human Proteins

A blocking peptide stabilizes lysophosphatidic acid receptor 1 and promotes lysophosphatidic acid‐induced cellular responses

Journal of Cellular Biochemistry ◽

10.1002/jcb.29919 ◽

2021 ◽

Author(s):

Sarah J Taleb ◽

Jianxin Wei ◽

Rachel K Mialki ◽

Su Dong ◽

Yanhui Li ◽

...

Keyword(s):

Lysophosphatidic Acid ◽

Cellular Responses ◽

Acid Receptor ◽

A lysophosphatidic acid receptor lacking the PDZ-binding domain is constitutively active and stimulates cell proliferation

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ◽

10.1016/j.bbamcr.2007.11.013 ◽

2008 ◽

Vol 1783 (5) ◽

pp. 748-759 ◽

Cited By ~ 51

Author(s):

Shinya Shano ◽

Kazuki Hatanaka ◽

Shinsuke Ninose ◽

Ryutaro Moriyama ◽

Toshifumi Tsujiuchi ◽

...

Keyword(s):

Cell Proliferation ◽

Lysophosphatidic Acid ◽

Binding Domain ◽

Acid Receptor ◽

Constitutively Active

Lysophosphatidic acid receptor 1 (LPAR1; EDG2; LPA1)

Science-Business eXchange ◽

10.1038/scibx.2011.1049 ◽

2011 ◽

Vol 4 (37) ◽

pp. 1049-1049

Keyword(s):

Lysophosphatidic Acid ◽

Acid Receptor ◽

The status of the lysophosphatidic acid receptor type 1 (LPA1R)

MedChemComm ◽

10.1039/c4md00333k ◽

2015 ◽

Vol 6 (1) ◽

pp. 13-23 ◽

Cited By ~ 9

Author(s):

Inés González-Gil ◽

Debora Zian ◽

Henar Vázquez-Villa ◽

Silvia Ortega-Gutiérrez ◽

María L. López-Rodríguez

Keyword(s):

Drug Development ◽

Lysophosphatidic Acid ◽

Receptor Type ◽

Current Status ◽

Acid Receptor ◽

The Status ◽

Development Pipeline

The current status of the LPA1receptor and its ligands in the drug development pipeline is reviewed.

Targeting lysophosphatidic acid receptor type 1 with Debio 0719 inhibits spontaneous metastasis dissemination of breast cancer cells independently of cell proliferation and angiogenesis

International Journal of Oncology ◽

10.3892/ijo.2011.1309 ◽

2011 ◽

Vol 40 (4) ◽

pp. 1133-1141 ◽

Cited By ~ 37

Author(s):

MARION DAVID ◽

JOHNNY RIBEIRO ◽

FRANÇOISE DESCOTES ◽

CLAIRE-MARIE SERRE ◽

MARYSE BARBIER ◽

...

Keyword(s):

Breast Cancer ◽

Cell Proliferation ◽

Cancer Cells ◽

Lysophosphatidic Acid ◽

Breast Cancer Cells ◽

Receptor Type ◽

Spontaneous Metastasis ◽

Acid Receptor ◽