The status of the lysophosphatidic acid receptor type 1 (LPA1R)

MedChemComm ◽  
2015 ◽  
Vol 6 (1) ◽  
pp. 13-23 ◽  
Author(s):  
Inés González-Gil ◽  
Debora Zian ◽  
Henar Vázquez-Villa ◽  
Silvia Ortega-Gutiérrez ◽  
María L. López-Rodríguez
Keyword(s):  
Drug Development ◽  
Lysophosphatidic Acid ◽  
Receptor Type ◽  
Current Status ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor ◽  
The Status ◽  
Development Pipeline

The current status of the LPA1receptor and its ligands in the drug development pipeline is reviewed.

scholarly journals Lysophosphatidic Acid Receptor Type 1 (LPA1) Plays a Functional Role in Osteoclast Differentiation and Bone Resorption Activity

2014 ◽  
Vol 289 (10) ◽  
pp. 6551-6564 ◽  
Author(s):  
Marion David ◽  
Irma Machuca-Gayet ◽  
Junichi Kikuta ◽  
Penelope Ottewell ◽  
Fuka Mima ◽  
...  
Keyword(s):  
Bone Resorption ◽  
Lysophosphatidic Acid ◽  
Functional Role ◽  
Osteoclast Differentiation ◽  
Receptor Type ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor

scholarly journals Modulation of Pro-inflammatory Gene Expression by Nuclear Lysophosphatidic Acid Receptor Type-1

2003 ◽  
Vol 278 (40) ◽  
pp. 38875-38883 ◽  
Author(s):  
Fernand Gobeil ◽  
Sylvie G. Bernier ◽  
Alejandro Vazquez-Tello ◽  
Sonia Brault ◽  
Martin H. Beauchamp ◽  
...  
Keyword(s):  
Gene Expression ◽  
Lysophosphatidic Acid ◽  
Receptor Type ◽  
Inflammatory Gene Expression ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor ◽  
Inflammatory Gene

scholarly journals Evaluation of the Lysophosphatidic Acid Receptor Type 1 Radioligand 11C-BMT-136088 for Lung Imaging in Rhesus Monkeys

2017 ◽  
Vol 59 (2) ◽  
pp. 327-333 ◽  
Author(s):  
Jean-Dominique Gallezot ◽  
Nabeel B. Nabulsi ◽  
Daniel Holden ◽  
Shu-Fei Lin ◽  
David Labaree ◽  
...  
Keyword(s):  
Lysophosphatidic Acid ◽  
Rhesus Monkeys ◽  
Receptor Type ◽  
Lung Imaging ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor

scholarly journals Activation of Lysophosphatidic Acid Receptor Type 1 Contributes to Pathophysiology of Spinal Cord Injury

2015 ◽  
Vol 35 (28) ◽  
pp. 10224-10235 ◽  
Author(s):  
E. Santos-Nogueira ◽  
C. Lopez-Serrano ◽  
J. Hernandez ◽  
N. Lago ◽  
A. M. Astudillo ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Lysophosphatidic Acid ◽  
Receptor Type ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor ◽  
Cord Injury

scholarly journals The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases

2006 ◽  
Vol 103 (25) ◽  
pp. 9643-9648 ◽  
Author(s):  
A. Boucharaba ◽  
C.-M. Serre ◽  
J. Guglielmi ◽  
J.-C. Bordet ◽  
P. Clezardin ◽  
...  
Keyword(s):  
Bone Metastases ◽  
Lysophosphatidic Acid ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor

scholarly journals MP09-01 EFFECT OF ASP6432, A TYPE 1 LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONIST, ON URETHRAL FUNCTION DURING THE VOIDING PHASE IN RATS

2018 ◽  
Vol 199 (4S) ◽  
Author(s):  
Kazuyuki Sakamoto ◽  
Yukiko Noguchi ◽  
Katsunori Imazumi ◽  
Koji Ueshima ◽  
Akiyoshi Ohtake ◽  
...  
Keyword(s):  
Receptor Antagonist ◽  
Lysophosphatidic Acid ◽  
Acid Receptor ◽  
Lysophosphatidic Acid Receptor ◽  
Urethral Function
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