Predicting human plasma protein binding of drugs using plasma protein interaction QSAR analysis (PPI-QSAR)

2011 ◽  
Vol 32 (6) ◽  
pp. 333-342 ◽  
Author(s):  
Haiyan Li ◽  
Zhuxi Chen ◽  
Xuejun Xu ◽  
Xiaofan Sui ◽  
Tao Guo ◽  
...  
Keyword(s):  
Protein Binding ◽  
Human Plasma ◽  
Plasma Protein Binding ◽  
Plasma Protein ◽  
Protein Interaction ◽  
Qsar Analysis ◽  
Human Plasma Protein ◽  
Protein Binding Of Drugs

Time-Series QSAR Analysis of Human Plasma Protein Binding Data

2007 ◽  
Vol 26 (4) ◽  
pp. 511-521 ◽  
Author(s):  
Sarah L. Rodgers ◽  
Andrew M. Davis ◽  
Han van de Waterbeemd
Keyword(s):  
Time Series ◽  
Protein Binding ◽  
Human Plasma ◽  
Plasma Protein Binding ◽  
Plasma Protein ◽  
Qsar Analysis ◽  
Human Plasma Protein ◽  
Binding Data

A novel strategy for prediction of human plasma protein binding using machine learning techniques

2020 ◽  
Vol 199 ◽  
pp. 103962
Author(s):  
Yawen Yuan ◽  
Shuo Chang ◽  
Zheng Zhang ◽  
Zhigang Li ◽  
Size Li ◽  
...  
Keyword(s):  
Machine Learning ◽  
Protein Binding ◽  
Human Plasma ◽  
Plasma Protein Binding ◽  
Plasma Protein ◽  
Machine Learning Techniques ◽  
Human Plasma Protein ◽  
Learning Techniques ◽  
Novel Strategy

Prediction models of human plasma protein binding rate and oral bioavailability derived by using GA–CG–SVM method

2008 ◽  
Vol 47 (4-5) ◽  
pp. 677-682 ◽  
Author(s):  
Chang-Ying Ma ◽  
Sheng-Yong Yang ◽  
Hui Zhang ◽  
Ming-Li Xiang ◽  
Qi Huang ◽  
...  
Keyword(s):  
Protein Binding ◽  
Human Plasma ◽  
Plasma Protein Binding ◽  
Plasma Protein ◽  
Oral Bioavailability ◽  
Prediction Models ◽  
Human Plasma Protein ◽  
Binding Rate

In Silico Prediction of Human Plasma Protein Binding Using Hologram QSAR

2007 ◽  
Vol 4 (7) ◽  
pp. 502-509 ◽  
Author(s):  
Tiago Moda ◽  
Carlos Montanari ◽  
Adriano Andricopulo
Keyword(s):  
Protein Binding ◽  
Human Plasma ◽  
Plasma Protein Binding ◽  
Plasma Protein ◽  
In Silico ◽  
In Silico Prediction ◽  
Human Plasma Protein

Evaluation of Human Plasma Protein Binding of Trabectedin (Yondelis™, ET-743)

2009 ◽  
Vol 4 (1) ◽  
pp. 38-42 ◽  
Author(s):  
Jan Beumer ◽  
L. Lopez-Lazaro ◽  
Jan Schellens ◽  
Jos Beijnen ◽  
Olaf Tellingen
Keyword(s):  
Protein Binding ◽  
Human Plasma ◽  
Plasma Protein Binding ◽  
Plasma Protein ◽  
Human Plasma Protein

QSAR Modeling Using Automatically Updating Correction Libraries:  Application to a Human Plasma Protein Binding Model

2007 ◽  
Vol 47 (6) ◽  
pp. 2401-2407 ◽  
Author(s):  
Sarah L. Rodgers ◽  
Andrew M. Davis ◽  
Nick P. Tomkinson ◽  
Han van de Waterbeemd
Keyword(s):  
Protein Binding ◽  
Human Plasma ◽  
Plasma Protein Binding ◽  
Plasma Protein ◽  
Qsar Modeling ◽  
Binding Model ◽  
Human Plasma Protein

Improved solubility and pharmacokinetics of PEGylated liposomal honokiol and human plasma protein binding ability of honokiol

2011 ◽  
Vol 410 (1-2) ◽  
pp. 169-174 ◽  
Author(s):  
Xian-Huo Wang ◽  
Lu-Lu Cai ◽  
Xiao-Yan Zhang ◽  
Lin-Yu Deng ◽  
Hao Zheng ◽  
...  
Keyword(s):  
Protein Binding ◽  
Human Plasma ◽  
Plasma Protein Binding ◽  
Plasma Protein ◽  
Binding Ability ◽  
Human Plasma Protein

Rat and human plasma protein binding of die main metabolite of triflusal

1990 ◽  
Vol 183 (5) ◽  
pp. 1867-1868 ◽  
Author(s):  
J. Ramis ◽  
R. Mis ◽  
L. Conte ◽  
J. Forn
Keyword(s):  
Protein Binding ◽  
Human Plasma ◽  
Plasma Protein Binding ◽  
Plasma Protein ◽  
Main Metabolite ◽  
Human Plasma Protein

Effect of in vivo Increase of Free Fatty Acids on Human Plasma Protein Binding of Furosemide

Pharmacology ◽  
1982 ◽  
Vol 25 (2) ◽  
pp. 73-81 ◽  
Author(s):  
Roberto Colombo ◽  
Arnaldo Pinelli
Keyword(s):  
Fatty Acids ◽  
Protein Binding ◽  
Free Fatty Acids ◽  
Human Plasma ◽  
Plasma Protein Binding ◽  
Plasma Protein ◽  
Human Plasma Protein
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