scholarly journals Effects of in utero exposure to Bisphenol A or diethylstilbestrol on the adult male reproductive system

Author(s):  
Jessica LaRocca ◽  
Alanna Boyajian ◽  
Caitlin Brown ◽  
Stuart Duncan Smith ◽  
Mary Hixon
2017 ◽  
Vol 32 (1-2) ◽  
pp. 73-81 ◽  
Author(s):  
Erin P. Madeen ◽  
David E. Williams

Abstract The male reproductive system is acutely and uniquely sensitive to a variety of toxicities, including those induced by environmental pollutants throughout the lifespan. Early life hormonal and morphological development results in several especially sensitive critical windows of toxicity risk associated with lifelong decreased reproductive health and fitness. Male factor infertility can account for over 40% of infertility in couples seeking treatment, and 44% of infertile men are diagnosed with idiopathic male infertility. Human environmental exposures are poorly understood due to limited available data. The latency between maternal and in utero exposure and a diagnosis in adulthood complicates the correlation between environmental exposures and infertility. The results from this review include recommendations for more and region specific monitoring of polycyclic aromatic hydrocarbon (PAH) exposure, longitudinal and clinical cohort considerations of exposure normalization, gene-environment interactions, in utero exposure studies, and controlled mechanistic animal experiments. Additionally, it is recommended that detailed semen analysis and male fertility data be included as endpoints in environmental exposure cohort studies due to the sensitivity of the male reproductive system to environmental pollutants, including PAHs.


2012 ◽  
Vol 2 (1_suppl) ◽  
pp. s-0032-1319931-s-0032-1319931
Author(s):  
S. Al Rowas ◽  
R. Gawri ◽  
R. Haddad ◽  
A. Almaawi ◽  
L. E. Chalifour ◽  
...  

2002 ◽  
Vol 16 (2) ◽  
pp. 117-122 ◽  
Author(s):  
Shizuka Honma ◽  
Atsuko Suzuki ◽  
David L. Buchanan ◽  
Yoshinao Katsu ◽  
Hajime Watanabe ◽  
...  

2020 ◽  
Vol 11 ◽  
Author(s):  
Federica Cariati ◽  
Luigi Carbone ◽  
Alessandro Conforti ◽  
Francesca Bagnulo ◽  
Stefania Ramona Peluso ◽  
...  

2008 ◽  
Vol 49 (5) ◽  
pp. 843 ◽  
Author(s):  
Mei Hua Jin ◽  
Hae Kyung Ko ◽  
Chang Hee Hong ◽  
Sang Won Han

2011 ◽  
Vol 2011 (1) ◽  
Author(s):  
Yun-jung Yang ◽  
Mun-seo Park ◽  
Sang-yon Kim ◽  
Lee-so Maeng ◽  
Soon-chul Myoung ◽  
...  

2008 ◽  
Vol 130 (4) ◽  
pp. 749-759 ◽  
Author(s):  
József Jászai ◽  
Christine A. Fargeas ◽  
Michael Haase ◽  
Lilla M. Farkas ◽  
Wieland B. Huttner ◽  
...  

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