Expression of viral capsid protein antigen against Epstein-Barr virus in plastids ofNicotiana tabacum cv. SR1

2006 ◽  
Vol 94 (6) ◽  
pp. 1129-1137 ◽  
Author(s):  
Maggie Y.T. Lee ◽  
Yuanxiang Zhou ◽  
Raymond W.M. Lung ◽  
Mee-Len Chye ◽  
Wing-Kin Yip ◽  
...  
Keyword(s):  
Capsid Protein ◽  
Epstein Barr Virus ◽  
Protein Antigen ◽  
Viral Capsid ◽  
Viral Capsid Protein ◽  
Barr Virus ◽  
Ofnicotiana Tabacum ◽  
Epstein Barr

Characterization of a 75-kDa epstein-barr virus capsid protein using a new monoclonal antibody H250

1989 ◽  
Vol 140 ◽  
pp. 531-543 ◽  
Author(s):  
A. Sanchez-Pinel ◽  
J. Bernad ◽  
H. Rives ◽  
J. Icart ◽  
J. Didier
Keyword(s):  
Monoclonal Antibody ◽  
Capsid Protein ◽  
Epstein Barr Virus ◽  
Virus Capsid ◽  
Barr Virus ◽  
Epstein Barr ◽  
Virus Capsid Protein

Increased incidence of IgA antibodies to the epstein-barr virus-associated viral capsid antigen and early antigens in patients with chronic lymphocytic leukemia

1986 ◽  
Vol 38 (1) ◽  
pp. 55-59 ◽  
Author(s):  
Gottfried Döucen ◽  
Klaus J. Bross ◽  
Thomas Hecht ◽  
Wolfram Brugger ◽  
Georg W. Löhr ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Epstein Barr Virus ◽  
Lymphocytic Leukemia ◽  
Viral Capsid ◽  
Viral Capsid Antigen ◽  
Barr Virus ◽  
Iga Antibodies ◽  
Epstein Barr

Comparison of immunofluorescence assay and multiplexed microparticle-based immunoassay for detecting Epstein-Barr virus viral capsid antigen antibodies

2008 ◽  
Vol 148 (1-2) ◽  
pp. 300-302 ◽  
Author(s):  
Aysin Zeytinoglu ◽  
Imre Altuglu ◽  
Eylem Karatas ◽  
Ruchan Yazan Sertoz
Keyword(s):  
Epstein Barr Virus ◽  
Immunofluorescence Assay ◽  
Viral Capsid ◽  
Viral Capsid Antigen ◽  
Barr Virus ◽  
Epstein Barr

Development of a time-resolved fluoroimmunoassay for Epstein–Barr virus viral capsid antigen IgA antibody in human serum

2015 ◽  
Vol 222 ◽  
pp. 16-21 ◽  
Author(s):  
Qian-Ni Liang ◽  
Pei-Qi Chen ◽  
Tian-Cai Liu ◽  
Jian-Wei Zhou ◽  
Juan-Juan Chen ◽  
...  
Keyword(s):  
Human Serum ◽  
Epstein Barr Virus ◽  
Viral Capsid ◽  
Viral Capsid Antigen ◽  
Time Resolved ◽  
Barr Virus ◽  
Iga Antibody ◽  
Epstein Barr

scholarly journals Transient Headache and Neurological Deficits with Cerebrospinal Fluid Lymphocytosis Associated with IgM Antibodies to the Epstein-Barr Virus Viral Capsid Antigen

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Kossivi Apetse ◽  
Ludovic Breynaert ◽  
Chloe Butaud ◽  
Albert Beschet ◽  
Karine Blanc-Lasserre ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Epstein Barr Virus ◽  
Immunological Response ◽  
Neurological Deficits ◽  
Viral Capsid ◽  
Viral Agent ◽  
Viral Capsid Antigen ◽  
Barr Virus ◽  
Igm Antibodies ◽  
Epstein Barr

Some authors have suggested that the syndrome of transient headache and neurological deficits with cerebrospinal fluid lymphocytosis (HaNDL) results from an immunological response directed against a viral agent. Here we report a case of HaNDL in an immunocompetent 19-year-old male that could support this hypothesis.

scholarly journals Self-Assembly of Epstein-Barr Virus Capsids

2009 ◽  
Vol 83 (8) ◽  
pp. 3877-3890 ◽  
Author(s):  
Brandon W. Henson ◽  
Edward M. Perkins ◽  
Jonathan E. Cothran ◽  
Prashant Desai
Keyword(s):  
Amino Acids ◽  
Capsid Protein ◽  
Self Assembly ◽  
Epstein Barr Virus ◽  
Major Capsid Protein ◽  
Mutational Analysis ◽  
Capsid Assembly ◽  
Barr Virus ◽  
Capsid Shell ◽  
Epstein Barr

ABSTRACT Epstein-Barr virus (EBV), a member of the Gammaherpesvirus family, primarily infects B lymphocytes and is responsible for a number of lymphoproliferative diseases. The molecular genetics of the assembly pathway and high-resolution structural analysis of the capsid have not been determined for this lymphocryptovirus. As a first step in studying EBV capsid assembly, the baculovirus expression vector (BEV) system was used to express the capsid shell proteins BcLF1 (major capsid protein), BORF1 (triplex protein), BDLF1 (triplex protein), and BFRF3 (small capsid protein); the internal scaffold protein, BdRF1; and the maturational protease (BVRF2). Coinfection of insect cells with the six viruses expressing these proteins resulted in the production of closed capsid structures as judged by electron microscopy and sedimentation methods. Therefore, as shown for other herpesviruses, only six proteins are required for EBV capsid assembly. Furthermore, the small capsid protein of EBV (BFRF3), like that of Kaposi's sarcoma-associated herpesvirus, was found to be required for assembly of a stable structure. Localization of the small capsid protein to nuclear assembly sites required both the major capsid (BcLF1) and scaffold proteins (BdRF1) but not the triplex proteins. Mutational analysis of BFRF3 showed that the N-terminal half (amino acids 1 to 88) of this polypeptide is required and sufficient for capsid assembly. A region spanning amino acids 65 to 88 is required for the concentration of BFRF3 at a subnuclear site and the N-terminal 65 amino acids contain the sequences required for interaction with major capsid protein. These studies have identified the multifunctional role of the gammaherpesvirus small capsid proteins.

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