Evaluation of a sterile filtration process for viral vaccines using a model nanoparticle suspension

2020 ◽  
Vol 118 (1) ◽  
pp. 106-115 ◽  
Author(s):  
Neil Taylor ◽  
Wanli Ma ◽  
Adam Kristopeit ◽  
Sheng‐Ching Wang ◽  
Andrew L. Zydney

2022 ◽  
pp. 120264
Author(s):  
Neil Taylor ◽  
Wanli (Justin) Ma ◽  
Adam Kristopeit ◽  
Sheng-Ching Wang ◽  
Andrew L. Zydney


Author(s):  
Zhi-Biao Wang ◽  
Pu Shan ◽  
Duo-qian Wei ◽  
Shao-jie Hao ◽  
Zhuan Zhang ◽  
...  


2017 ◽  
Vol 01 (01) ◽  
Author(s):  
Tirasak Pasharawipas
Keyword(s):  


2018 ◽  
pp. 99-107
Author(s):  
V. V. Lavrov ◽  
R. S. Luchkin ◽  
O. I. Nemykin ◽  
M. E. Prokhorov ◽  
Yu. G. Ryndin ◽  
...  

Methods and algorithms for the complete processing of a post-detector low-contrast optical image (OI) of an unknown remote object obtained by ground-based optical means of observation under conditions of a complex background situation are considered. The purpose of processing is to separate and interpret at least with the help of the analyst, of the main constructive elements using the integrated indicators introduced in [6] and the characteristics of the analyzed OI, which are connected by the information, topological and metric structures of the OI. The stages of processing the OI include extracting the image-containing information object of the image portion (detection) and filtration of the OI, using recursive rank filtering. The final stages of processing include the segmentation of the OI and the allocation on it constructive elements using the apparatus of graph theory. An example of image processing of a Spot-5 spacecraft obtained in real conditions is given. It is shown that in this case at the detection stage it is possible to reduce the volume of information processed at subsequent stages by 8 times, in the filtration process to increase the compactness of the OI and to increase its connectivity in comparison with the post-detection OI. As a result of segmentation and allocation of constructive elements, three structural elements that can be interpreted as a spacecraft case and two remote panels can be identified with the analyst’s participation.



2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Tanja Opriessnig ◽  
Ashley A. Mattei ◽  
Anbu K. Karuppannan ◽  
Patrick G. Halbur

AbstractDeliberate infection of humans with smallpox, also known as variolation, was a common practice in Asia and dates back to the fifteenth century. The world’s first human vaccination was administered in 1796 by Edward Jenner, a British physician. One of the first pig vaccines, which targeted the bacterium Erysipelothrix rhusiopathiae, was introduced in 1883 in France by Louis Pasteur. Since then vaccination has become an essential part of pig production, and viral vaccines in particular are essential tools for pig producers and veterinarians to manage pig herd health. Traditionally, viral vaccines for pigs are either based on attenuated-live virus strains or inactivated viral antigens. With the advent of genomic sequencing and molecular engineering, novel vaccine strategies and tools, including subunit and nucleic acid vaccines, became available and are being increasingly used in pigs. This review aims to summarize recent trends and technologies available for the production and use of vaccines targeting pig viruses.



2021 ◽  
Vol 1047 (1) ◽  
pp. 012042
Author(s):  
P A Kustashev ◽  
L A Kazakovtsev ◽  
I P Rozhnov ◽  
I N Kirikov ◽  
E P Burmistrov


Author(s):  
Rosiah Rohani ◽  
Izzati Izni Yusoff ◽  
Nadiah Khairul Zaman ◽  
Arshid Mahmood Ali ◽  
Nadiatul Atalia Balqis Rusli ◽  
...  


Foods ◽  
2021 ◽  
Vol 10 (8) ◽  
pp. 1677
Author(s):  
Biagi Angelo Zullo ◽  
Giulia Venditti ◽  
Gino Ciafardini

Filtration is a widely used process in the production of extra virgin olive oil. We studied the influence of filtration performed with cotton filters and cellulose filter press on the biotic components of the oily mass containing probiotic traits in two freshly produced monocultivar extra virgin olive oils. The concentration of bacteria was reduced from 100% to 28%, while that of fungi was reduced from 100% to 44% after filtration, according to the filtration system and the initial contamination of the original monocultivar extra virgin olive oil. Compared with the control, the yeast content in the oil samples filtered with cotton filters was reduced from 37% to 11% depending on the cultivar. In the oil filtered with cellulose filter press, the yeast content reduced from 42% to 16%. The viable yeast that passed through the oily mass during the filtration process with cellulose filter press, unlike all the other samples, were unable to survive in the oil after a month of storage. The possible health benefits of compounds from both the biotic and abiotic fraction of the oil, compared to the control, were significantly low when filtered with the cellulose filter press.





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