Cross-scale predictive modeling of CHO cell culture growth and metabolites using Raman spectroscopy and multivariate analysis

2014 ◽  
Vol 31 (2) ◽  
pp. 566-577 ◽  
Author(s):  
Brandon Berry ◽  
Justin Moretto ◽  
Thomas Matthews ◽  
John Smelko ◽  
Kelly Wiltberger
Keyword(s):  
Cell Culture ◽  
Raman Spectroscopy ◽  
Multivariate Analysis ◽  
Predictive Modeling ◽  
Cho Cell ◽  
Cho Cell Culture ◽  
Culture Growth ◽  
Cell Culture Growth

scholarly journals Identifying Inhibitory Threshold Values of Repressing Metabolites in CHO Cell Culture Using Multivariate Analysis Methods

2008 ◽  
Vol 24 (3) ◽  
pp. 675-683 ◽  
Author(s):  
Z. Xing ◽  
Z. Li ◽  
V. Chow ◽  
S.S. Lee
Keyword(s):  
Cell Culture ◽  
Multivariate Analysis ◽  
Threshold Values ◽  
Cho Cell ◽  
Analysis Methods ◽  
Cho Cell Culture ◽  
Inhibitory Threshold

scholarly journals Benchmarking of commercially available CHO cell culture media for antibody production

2015 ◽  
Vol 99 (11) ◽  
pp. 4645-4657 ◽  
Author(s):  
David Reinhart ◽  
Lukas Damjanovic ◽  
Christian Kaisermayer ◽  
Renate Kunert
Keyword(s):  
Cell Culture ◽  
Antibody Production ◽  
Culture Media ◽  
Cho Cell ◽  
Cell Culture Media ◽  
Cho Cell Culture

scholarly journals Equal mixing time enables scale‐down and optimisation of a CHO cell culture process using a shaken microbioreactor system

2021 ◽  
Author(s):  
Vincent Wiegmann ◽  
Richard A. Gardner ◽  
Daniel I. R. Spencer ◽  
Frank Baganz
Keyword(s):  
Cell Culture ◽  
Mixing Time ◽  
Cell Culture Process ◽  
Cho Cell ◽  
Scale Down ◽  
Culture Process ◽  
Cho Cell Culture

scholarly journals Reduction of charge variants by CHO cell culture process optimization

2020 ◽  
Vol 72 (2) ◽  
pp. 259-269 ◽  
Author(s):  
Zhibing Weng ◽  
Jian Jin ◽  
ChunHua Shao ◽  
Huazhong Li
Keyword(s):  
Cell Culture ◽  
Process Optimization ◽  
Cell Culture Process ◽  
Cho Cell ◽  
Culture Process ◽  
Cho Cell Culture ◽  
Charge Variants

CONTINUOUS SUSPENSION CHO CELL CULTURE

1994 ◽  
pp. 215-217
Author(s):  
Henrik Albahn Hansen ◽  
Claus Emborg
Keyword(s):  
Cell Culture ◽  
Cho Cell ◽  
Cho Cell Culture

An investigation of nucleotide sugar dynamics under the galactose supplementation in CHO cell culture

2019 ◽  
Vol 81 ◽  
pp. 165-174 ◽  
Author(s):  
Sha Sha ◽  
Seongkyu Yoon
Keyword(s):  
Cell Culture ◽  
Cho Cell ◽  
Nucleotide Sugar ◽  
Cho Cell Culture

Model‐based optimization of antibody galactosylation in CHO cell culture

2019 ◽  
Vol 116 (7) ◽  
pp. 1612-1626 ◽  
Author(s):  
Pavlos Kotidis ◽  
Philip Jedrzejewski ◽  
Si Nga Sou ◽  
Christopher Sellick ◽  
Karen Polizzi ◽  
...  
Keyword(s):  
Cell Culture ◽  
Cho Cell ◽  
Model Based ◽  
Cho Cell Culture

scholarly journals Novel column generation-based optimization approach for poly-pathway kinetic model applied to CHO cell culture

2019 ◽  
Vol 8 ◽  
pp. e00083 ◽  
Author(s):  
Erika Hagrot ◽  
Hildur Æsa Oddsdóttir ◽  
Meeri Mäkinen ◽  
Anders Forsgren ◽  
Véronique Chotteau
Keyword(s):  
Cell Culture ◽  
Kinetic Model ◽  
Column Generation ◽  
Optimization Approach ◽  
Cho Cell ◽  
Cho Cell Culture

scholarly journals Dynamics of immature mAb glycoform secretion during CHO cell culture: An integrated modelling framework

2016 ◽  
Vol 11 (5) ◽  
pp. 610-623 ◽  
Author(s):  
Ioscani Jimenez del Val ◽  
Yuzhou Fan ◽  
Dietmar Weilguny
Keyword(s):  
Cell Culture ◽  
Integrated Modelling ◽  
Cho Cell ◽  
Modelling Framework ◽  
Cho Cell Culture
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