Hyperactive/impulsive symptoms and autistic trait in institutionalized children with maltreatment experience

Author(s):  
Junko Imai ◽  
Daimei Sasayama ◽  
Rie Kuge ◽  
Hideo Honda ◽  
Shinsuke Washizuka
2020 ◽  
Vol 45 (3) ◽  
pp. 309-326 ◽  
Author(s):  
Said Baadel ◽  
Fadi Thabtah ◽  
Joan Lu

2017 ◽  
Vol 75 ◽  
pp. 61-68 ◽  
Author(s):  
Claudia Caprin ◽  
Laura Benedan ◽  
Luigina Ballarin ◽  
Alessia Gallace

1983 ◽  
Vol 28 (7) ◽  
pp. 575-581 ◽  
Author(s):  
Beatriz R. de Muñiz ◽  
Beatriz M. Maresca ◽  
O.R. Tumilasci ◽  
C.J. Perec

2021 ◽  
pp. 1-10
Author(s):  
Mark J. Taylor ◽  
Angelica Ronald ◽  
Joanna Martin ◽  
Sebastian Lundström ◽  
Georgina M. Hosang ◽  
...  

Abstract Background There is evidence that autism spectrum disorders (ASDs) co-occur with bipolar disorder (BD) relatively frequently. Individuals with BD often report symptoms of mania and hypomania during adolescence, prior to the age of onset for BD. It is unknown whether these symptoms are associated with ASDs. We examined whether diagnoses of ASDs and autistic traits were associated with hypomania in a large, population-based Swedish twin sample. Methods Parental structured interviews assessed autistic traits, and were used to assign screening diagnoses of ASDs, when twins were aged 9 or 12 (N = 13 533 pairs). Parents then completed questionnaires assessing hypomania when the twins were aged 15 and 18 (N = 3852 pairs at age 15, and 3013 pairs at age 18). After investigating the phenotypic associations between these measures, we used the classical twin design to test whether genetic and environmental influences on autistic traits influence variation in adolescent hypomania. Results Autistic traits and ASD diagnoses in childhood were associated with elevated scores on the measures of adolescent hypomania. Twin analyses indicated that 6–9% of the variance in hypomania was explained by genetic influences that were shared with autistic traits in childhood. When repeating these analyses for specific autistic trait domains, we found a stronger association between social interaction difficulties and hypomania than for other autistic trait domains. Conclusions These results indicate a genetic link between autistic traits and hypomania in adolescence. This adds to the growing evidence base of genetic factors associated with ASDs showing links with psychiatric outcomes across childhood and into adulthood.


2018 ◽  
Vol 50 (3) ◽  
pp. 425-438 ◽  
Author(s):  
Yuning Zhang ◽  
Charlotte C. A. M. Cecil ◽  
Edward D. Barker ◽  
Shigeyuki Mori ◽  
Jennifer Y. F. Lau

2020 ◽  
Author(s):  
Olessia Jouravlev ◽  
Alexander J.E. Kell ◽  
Zachary Mineroff ◽  
A.J. Haskins ◽  
Dima Ayyash ◽  
...  

AbstractOne of the few replicated functional brain differences between individuals with autism spectrum disorders (ASD) and neurotypical (NT) controls is reduced language lateralization. However, most prior reports relied on comparisons of group-level activation maps or functional markers that had not been validated at the individual-subject level, and/or used tasks that do not isolate language processing from other cognitive processes, complicating interpretation. Furthermore, few prior studies have examined functional responses in other functional networks, as needed to determine the selectivity of the effect. Using fMRI, we compared language lateralization between 28 ASD participants and carefully pairwise-matched controls, with the language regions defined individually with a well-validated language localizer. ASD participants showed less lateralized responses due to stronger right hemisphere activations. Further, this effect did not stem from a ubiquitous reduction in lateralization across the brain: ASD participants did not differ from controls in the lateralization of two other large-scale networks—the Theory of Mind network and the Multiple Demand network. Finally, in an exploratory study, we tested whether reduced language lateralization may also be present in NT individuals with high autistic trait load. Indeed, autistic trait load in a large set of NT participants (n=189) was associated with less lateralized language activations. These results suggest that reduced language lateralization is a robust and spatially selective neural marker of autism, present in individuals with ASD, but also in NT individuals with higher genetic liability for ASD, in line with a continuum model of underlying genetic risk.


2021 ◽  
Author(s):  
Cassia L. McIntyre ◽  
Troy Boucher ◽  
Nichole Scheerer ◽  
Mandeep Gurm ◽  
Grace Iarocci

Alexithymia impacts an individual’s ability to recognize and understand emotions and frequently co-occurs with autism. This study investigated the relationship between children’s alexithymia, autistic traits, and caregiver reactions to their child’s negative emotions. Caregivers of 54 autistic and 51 non-autistic children between the ages of 7 and 12 years rated their child’s alexithymia and autistic trait severity and their reactions to their child’s negative emotions. Caregivers of autistic children reported greater supportive reactions and fewer restrictive/controlling reactions to their child’s negative emotions when their child had more alexithymia traits. This study extends previous research by demonstrating that caregivers of autistic children with co-occurring alexithymia traits represent a specific subgroup of caregivers that respond more positively to their child’s negative emotions.


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