Erythrocyte sodium pump stimulation by ouabain and an endogenous ouabain-like factor

2007 ◽  
Vol 25 (3) ◽  
pp. 297-303 ◽  
Author(s):  
Silvana Balzan ◽  
Giuseppina D'Urso ◽  
Giuseppina Nicolini ◽  
Francesca Forini ◽  
Mario Pellegrino ◽  
...  
Keyword(s):  
Sodium Pump ◽  
Endogenous Ouabain ◽  
Erythrocyte Sodium

Is the Erythrocyte Sodium Pump Altered in Human Obesity?*

1983 ◽  
Vol 56 (5) ◽  
pp. 925-929 ◽  
Author(s):  
Bruce M. Simat ◽  
Robert R. Mayrand ◽  
Arthur H. L. From ◽  
John E. Morley ◽  
Charles Billington ◽  
...  
Keyword(s):  
Sodium Pump ◽  
Human Obesity ◽  
Erythrocyte Sodium

A serial study of erythrocyte sodium pump kinetics and sodium content in the puerperium

1994 ◽  
Vol 170 (2) ◽  
pp. 693-698 ◽  
Author(s):  
Lesley M. Bolton ◽  
Trevor H. Thomas ◽  
Sheila Macphail ◽  
William Dunlop
Keyword(s):  
Sodium Pump ◽  
Sodium Content ◽  
Erythrocyte Sodium

Relationship between the Maximum Velocity and Sodium Affinity of the Erythrocyte Sodium Pump and its Rate Constant in Blood

1990 ◽  
Vol 79 (6) ◽  
pp. 625-630 ◽  
Author(s):  
T. H. Thomas ◽  
S. MacPhail ◽  
V. Mott ◽  
R. Wilkinson
Keyword(s):  
Rate Constant ◽  
Whole Blood ◽  
Sodium Pump ◽  
Maximum Velocity ◽  
Normal Subjects ◽  
Affinity Constant ◽  
Pump Rate ◽  
Median Error ◽  
Data Points ◽  
Erythrocyte Sodium

1. Young and mature erythrocytes from 15 normal subjects were used to compare the sodium pump rate constant measured in whole blood with the more definitive sodium affinity constant and maximum velocity of the sodium pump measured in artificial media using sodium-loaded cells. 2. Similar values were obtained from both erythrocyte fractions for the sodium affinity constant and maximum velocity and also by using two different plots. The median error in the estimate of individual sodium affinity constants and maximum velocities from regression analysis was about 20% and the precision was not improved by combining the data points for the two erythrocyte fractions. 3. The rate constant in whole blood was closely related to the sodium affinity constant and maximum velocity of the sodium pump (r = 0.75), suggesting that it was a reasonable overall assessment of available sodium pump activity. 4. Differences in the rate constant between subjects were due to differences in both the maximum velocity and sodium affinity constant of the sodium pump so that the rate constant could not be used as a guide to the underlying sodium pump physiology.

The Endogenous Ouabain-Like Sodium Pump Inhibitor in Cold Injury-Induced Brain Edema

1994 ◽  
pp. 98-100
Author(s):  
Z. M. Rap ◽  
W. Schoner ◽  
Z. Czernicki ◽  
G. Hildebrandt ◽  
H. W. Mueller ◽  
...  
Keyword(s):  
Brain Edema ◽  
Sodium Pump ◽  
Cold Injury ◽  
Endogenous Ouabain

Erythrocyte Sodium Pump Activity in Diabetes Mellitus and its Relationship to Control and Microangiopathy

1985 ◽  
Vol 69 (s12) ◽  
pp. 44P-45P
Author(s):  
P.E. Jennings ◽  
M.R. Wilkins ◽  
M.J. West ◽  
M.J. Kendall ◽  
A.H. Barnett
Keyword(s):  
Diabetes Mellitus ◽  
Sodium Pump ◽  
Pump Activity ◽  
Erythrocyte Sodium

Age and sex differences of erythrocyte sodium pump activity in normal human subjects

1977 ◽  
Vol 76 (3) ◽  
pp. 399-401 ◽  
Author(s):  
Mabel Hokin-Neaverson ◽  
David A. Spiegel ◽  
William A. Burckhardt ◽  
James W. Jefferson
Keyword(s):  
Sex Differences ◽  
Sodium Pump ◽  
Human Subjects ◽  
Pump Activity ◽  
Normal Human ◽  
Erythrocyte Sodium ◽  
Age And Sex

Relationship of Erythrocyte Sodium Pump Kinetics to Pump Activity during Pregnancy

1989 ◽  
Vol 77 (s21) ◽  
pp. 29P-29P
Author(s):  
S MacPhail ◽  
T Thomas ◽  
R Wilkindson ◽  
JM Davison ◽  
W Dunlop
Keyword(s):  
Sodium Pump ◽  
Pump Activity ◽  
Erythrocyte Sodium ◽  
Relationship Of

scholarly journals Reduced number of erythrocyte sodium pump units in essential hypertension.

1984 ◽  
Vol 143 (3) ◽  
pp. 383-384 ◽  
Author(s):  
YOSHIAKI TAKAYAMA ◽  
KAZUO SUZUKI ◽  
AKIRA SEKI ◽  
KAZUHIDE YAMAOKI ◽  
JUN FUJII
Keyword(s):  
Essential Hypertension ◽  
Sodium Pump ◽  
Erythrocyte Sodium

A Serial Study of Erythrocyte Sodium Content and Sodium Pump Kinetics in Pregnancy

1990 ◽  
Vol 79 (6) ◽  
pp. 631-638 ◽  
Author(s):  
S. MacPhail ◽  
T. H. Thomas ◽  
R. Wilkinson ◽  
J. M. Davison ◽  
W. Dunlop
Keyword(s):  
Rate Constant ◽  
Whole Blood ◽  
Sodium Pump ◽  
Maximum Velocity ◽  
Sodium Content ◽  
Affinity Constant ◽  
Pump Rate ◽  
Erythrocyte Sodium ◽  
Sodium Pump Inhibition

1. Normotensive primigravid pregnant women were studied longitudinally during pregnancy and 20 weeks after delivery. 2. Erythrocyte sodium content, ouabain-sensitive sodium flux and sodium pump rate constant were measured in whole blood, and the maximum velocity and sodium affinity of the sodium pump were measured in vitro. 3. Erythrocyte sodium content decreased and the sodium pump rate constant increased up to 26 weeks gestation. The increase in rate constant was due to an increase in the affinity of the sodium pump for sodium up to 20 weeks gestation. After 20 weeks gestation there was an increase in maximum velocity and a decrease in sodium affinity of the sodium pump but no further change in the sodium pump rate constant. 4. At 14 weeks gestation the sodium pump rate constant was correlated with both the maximum velocity and sodium affinity constant. After this time the relationship was much more variable and there was no correlation with the sodium affinity constant. The comparison of measurements of the sodium pump in whole blood and in vitro gave no evidence of sodium pump inhibition. 5. The erythrocyte sodium pump changed throughout gestation with different components to the change, but, overall, available sodium pump activity in blood increased and sodium content decreased.

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