Sodium Nitrate Induces Reactive Oxygen Species That Lower the Antioxidant Power, Damage the Membrane, and Alter Pathways of Glucose Metabolism in Human Erythrocytes

2015 ◽  
Vol 63 (48) ◽  
pp. 10372-10379 ◽  
Author(s):  
Fariheen Aisha Ansari ◽  
Riaz Mahmood
Keyword(s):  
Reactive Oxygen Species ◽  
Glucose Metabolism ◽  
Sodium Nitrate ◽  
Reactive Oxygen ◽  
Human Erythrocytes ◽  
Oxygen Species ◽  
Antioxidant Power

Hexavalent chromium induces reactive oxygen species and impairs the antioxidant power of human erythrocytes and lymphocytes: Decreased metal reducing and free radical quenching ability of the cells

2017 ◽  
Vol 33 (8) ◽  
pp. 623-635 ◽  
Author(s):  
Nazim Husain ◽  
Riaz Mahmood
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Free Radicals ◽  
Free Radical ◽  
Hexavalent Chromium ◽  
Reactive Oxygen ◽  
Human Erythrocytes ◽  
Cellular Damage ◽  
Oxygen Species ◽  
Antioxidant Power

The toxicity of hexavalent chromium [Cr(VI)] in biological systems is thought to be closely associated with the generation of free radicals and reactive oxygen species. These species are produced when Cr(VI) is reduced to its trivalent form in the cell. This process results in oxidative stress due to an imbalance between the detoxifying ability of the cell and the production of free radicals. We have studied the effect of potassium dichromate (K2Cr2O7), a [Cr(VI)] compound, on the antioxidant power of human erythrocytes and lymphocytes under in vitro conditions. Incubation of erythrocytes and lymphocytes with different concentrations of K2Cr2O7 resulted in a marked dose-dependent decrease in reduced glutathione and an increase in oxidized glutathione and reactive oxygen species levels. The antioxidant power of the cells was decreased, as determined by metal reducing and free radical quenching assays. These results show that [Cr(VI)] upregulates the generation of reactive oxygen species and, as a consequence, the cellular antioxidant defences are compromised. The resulting oxidative stress may contribute to Cr(VI)-induced cellular damage.

scholarly journals Hypothalamic Apelin/Reactive Oxygen Species Signaling Controls Hepatic Glucose Metabolism in the Onset of Diabetes

2014 ◽  
Vol 20 (4) ◽  
pp. 557-573 ◽  
Author(s):  
Anne Drougard ◽  
Thibaut Duparc ◽  
Xavier Brenachot ◽  
Lionel Carneiro ◽  
Alexandra Gouazé ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Glucose Metabolism ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Hepatic Glucose Metabolism ◽  
Hepatic Glucose ◽  
Onset Of Diabetes ◽  
Reactive Oxygen Species Signaling

Selenium nanoparticles reduce glucose metabolism and promote apoptosis of glioma cells through reactive oxygen species-dependent manner

Neuroreport ◽  
2020 ◽  
Vol 31 (3) ◽  
pp. 226-234 ◽  
Author(s):  
Binchu Xu ◽  
Qingping Zhang ◽  
Xinlin Luo ◽  
Xinjie Ning ◽  
Juncheng Luo ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Glucose Metabolism ◽  
Glioma Cells ◽  
Reactive Oxygen ◽  
Selenium Nanoparticles ◽  
Dependent Manner ◽  
Oxygen Species

Reactive Oxygen Species, Glucose Metabolism, and Lipid Metabolism

2021 ◽  
pp. 213-235
Author(s):  
Ying Yang ◽  
Yue Wu ◽  
Xiao-Dong Sun ◽  
Yuanyuan Zhang
Keyword(s):  
Reactive Oxygen Species ◽  
Lipid Metabolism ◽  
Glucose Metabolism ◽  
Reactive Oxygen ◽  
Oxygen Species

scholarly journals Silver nanoparticles affect glucose metabolism in hepatoma cells through production of reactive oxygen species

2015 ◽  
pp. 55 ◽  
Author(s):  
Sun Park ◽  
Mi Jin Lee ◽  
Seung Jun Lee ◽  
Su Jin Yun ◽  
Ji-Young Jang ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Silver Nanoparticles ◽  
Glucose Metabolism ◽  
Reactive Oxygen ◽  
Hepatoma Cells ◽  
Oxygen Species

Fructose-1,6-bisphosphate preserves glucose metabolism integrity and reduces reactive oxygen species in the brain during experimental sepsis

2018 ◽  
Vol 1698 ◽  
pp. 54-61 ◽  
Author(s):  
Anderson V. Catarina ◽  
Carolina Luft ◽  
Samuel Greggio ◽  
Gianina T. Venturin ◽  
Fernanda Ferreira ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Glucose Metabolism ◽  
Reactive Oxygen ◽  
Experimental Sepsis ◽  
Oxygen Species ◽  
Fructose 1,6 Bisphosphate ◽  
The Brain
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