Transcatheter closure of acquired left ventricle to right atrium shunts

2013 ◽  
Vol 82 (6) ◽  
pp. E809-E814 ◽  
Author(s):  
Juha Sinisalo ◽  
Narayanswami Sreeram ◽  
Shakeel A. Qureshi
Medicine ◽  
2020 ◽  
Vol 99 (47) ◽  
pp. e22576
Author(s):  
Xiaoqing Shi ◽  
Kaiyang Wang ◽  
Jinhui Li ◽  
Jinlin Wu ◽  
Kaiyu Zhou ◽  
...  

Heart ◽  
1964 ◽  
Vol 26 (5) ◽  
pp. 584-591 ◽  
Author(s):  
R. B. Mellins ◽  
G. Cheng ◽  
K. Ellis ◽  
A. G. Jameson ◽  
J. R. Malm ◽  
...  

Author(s):  
RegienG. Schoemaker ◽  
XiaoY. Du ◽  
WillemA. Bax ◽  
PramodR. Saxena

2018 ◽  
Vol 58 (5) ◽  
pp. 213-20
Author(s):  
Devy Kusmira ◽  
Ria Nova ◽  
Achirul Bakri

Background Amino-terminal pro-B-type natriuretic peptide (NT-proBNP) levels before and after transcatheter closure may correlate with changes in left ventricular internal diameter end diastole (LVIDd) and end systole (LVIDs). Patent ductus arteriosus (PDA) and ventricular septal defect (VSD) are structural abnormalities which effects cardiac hypertrophy. Cardiac muscle stretching decreases after closure, followed by reduced left ventricle diameters and decreased NT-proBNP levels. Objective To analyze for possible correlations between NT-proBNP levels and left ventricle diameters before and after transcatheter closure. Methods Subjects were PDA and VSD patients who underwent transcatheter closure in the Pediatrics Department of dr. Moh Hoesin Hospital, Palembang, South Sumatera, from May 2016 to March 2017. Measurement of NT-proBNP levels and echocardiography were performed before closure, as well as one and three months after closure. Results There were 34 subjects (15 girls) with median age of 91.5 months. Median NT-proBNP levels were significantly reduced after closure: before closure 111.7pg/mL, one month after closure 62pg/mL, and three months after closure 39 pg/mL (P<0.05). Median LVIDd and LVIDs were also significantly reduced after closure [LVIDd: 39.5mm before, 34.5mm one mo after, and 32.5mm 3 mo after (P<0.05); LVIDs: 23.9mm before, 20.5mm 1 mo after, and 20.0mm 3 mo after (P<0.05)]. At one month after closure, there was a moderate positive correlation between NT-proBNP levels and LVIDd (r=0.432; P=0.011), but no correlation with LVIDs (r=0.287; P=0.100). At three months after closure, there was a significant moderate positive correlation between changes of NT-proBNP levels and changes of LVIDd (r=0.459; P=0.006), as well as LVIDs (r=0.563; P=0.001). Conclusion In pediatric PDA and VSD patients, NT-proBNP levels have a significant positive correlation with diastolic and systolic left ventricle diameters at three months after closure. Decreased NT-proBNP levels may be considered as a marker of closure effectiveness.


1976 ◽  
Vol 231 (3) ◽  
pp. 781-785 ◽  
Author(s):  
OM Brown

The distribution of acetylcholine (ACh) in the cat heart was investigated by a pyrolysis-gas chromatography (PGC) method. The hearts were dissected into various regions and homogenized in acetonitrile in the presence of propionylcholine, internal standard. Following extraction with toluene and hexane, the choline esters were precipitated as the enneaiodide complex. The isolated choline esters were analyzed by PGC, and the peak corresponding to ACh was quantified. The compound extracted from heart tissue that eluted with the retention time of authentic ACh was identified by mass spectrometry as dimethylaminoethylacetate, the pyrolysis product of ACh. ACh concentrations were found to be higher in the atria than the ventricles. In both the atria and the ventricles, a higher content of ACh was found in the right than the left portions: right ventricle, 5.0 compared to left ventricle, 2.0 nmol/g; and right atrium, 16.8 compared to left atrium, 11.3 nmol/g. Some cats were subjected to a bilateral cervical vagotomy 3 wk before removal and analysis of heart tissue. Hearts from vagotomized cats contained less ACh than controls in the right ventricle (-31%), right atrium (-54%), SA node (-42%), and papillary muscle (-53%), but no decreases were found in the left ventricle, left atrium, or interventricular septum.


2018 ◽  
Vol 26 (6) ◽  
pp. 496-497
Author(s):  
Richard Saldanha ◽  
Mohan Gan ◽  
Abhijeet Shitole

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