scholarly journals A case of adenomyoepithelioma with myoepithelial carcinoma of the breast

2019 ◽  
Vol 7 (5) ◽  
pp. 930-934 ◽  
Author(s):  
Ryota Ito ◽  
Daisuke Ota ◽  
Sumiyo Ando ◽  
Masaya Mori ◽  
Atsushi Fukuuchi
2000 ◽  
Vol 80 (6) ◽  
pp. 831-836 ◽  
Author(s):  
Chris Jones ◽  
Maria P Foschini ◽  
Ranbir Chaggar ◽  
Yong-J Lu ◽  
Dagan Wells ◽  
...  

2019 ◽  
Vol 104 (5-6) ◽  
pp. 203-210
Author(s):  
Hye Yoon Lee ◽  
Jeong Hyun Lee ◽  
Seung Pil Jung ◽  
Insun Kim ◽  
Jeoung Won Bae

Objectives Adenomyoepithelioma (AME) of the breast exhibits characteristic proliferation of the epithelial and myoepithelial cells. Most AMEs are benign, but the 2 inherent cell types can become malignant. The present study reports 2 cases of AME with myoepithelial carcinoma of the breast, one with axillary lymph node metastasis. Methods A modified radical mastectomy was performed in a 67-year-old woman, because a sentinel lymph node biopsy revealed one metastatic lymph node composed of a myoepithelial carcinoma component. Despite receiving radiotherapy and chemotherapy, the patient died from lung and brain metastases 21 months later. In the second case, breast-conserving surgery with sentinel lymph node biopsy was performed in a 55-year-old woman. Following additional treatment with radiotherapy and chemotherapy, there were no signs of recurrence or metastasis. Results The tumors of the 2 patients were diagnosed as malignant, based on their high mitotic rate and severe nuclear atypia. Conclusions Based on previously reported cases with distant metastases, the prognosis of myoepithelial carcinoma is poor. Myoepithelial carcinoma should be followed up with careful screening and treated aggressively.


2019 ◽  
Vol 25 (6) ◽  
pp. 1273-1275
Author(s):  
Aanchal Kakkar ◽  
Kirti Jangra ◽  
Navin Kumar ◽  
Mehar C. Sharma ◽  
Sandeep R. Mathur ◽  
...  

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Karl Grenier ◽  
Gulbeyaz Altinel ◽  
Zari Dastani ◽  
Atilla Omeroglu

Epithelial-myoepithelial carcinoma of the breast is a rare biphasic tumor composed of intermixed malignant epithelial and myoepithelial components. Myoepithelial cells are known to adopt varied morphologies, including spindle, chondroid, clear cell, and rhabdoid morphologies, and can represent a diagnostic challenge when isolated on biopsy. Rhabdomyosarcoma, phyllodes tumor, metaplastic carcinoma, and myoepithelial carcinoma are primary breast tumors that all have been shown to exhibit rhabdoid features, whether representing true differentiation or morphological mimic. We here report an epithelial-myoepithelial carcinoma of the breast with rhabdoid features in a 76-year-old woman. The rhabdoid-appearing myoepithelial cells are negative for myogenin, consistent with a rhabdoid-like morphology rather than a true rhabdoid differentiation, comparably to previously described myoepithelial carcinoma with rhabdoid features. To our knowledge, this is the first reported case of epithelial-myoepithelial carcinoma of the breast with rhabdoid features and thus adds another entity to the differential diagnosis of breast lesions with rhabdoid features.


2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Yumi Endo ◽  
Hiroshi Sugiura ◽  
Hiroko Yamashita ◽  
Satoru Takahashi ◽  
Nobuyasu Yoshimoto ◽  
...  

Myoepithelial carcinoma (malignant myoepithelioma) of the breast is a rare tumor, for which only a limited number of reports have been published. Most of the reports emphasized diagnosis and pathology but not biological behavior and treatment. We report a 61-year-old patient with breast myoepithelial carcinoma who developed locoregional and distant metastases and received many chemotherapy regimens. She presented with an elastic hard mass of the left breast. Breast conserving surgery was performed as part of both diagnosis and treatment. From the results of histological and immunohistochemical examinations, this case was considered to be a myoepithelial carcinoma. Fifteen months after the completion of adjuvant radiotherapy, distant metastasis of the left parasternal lymph node metastasis developed. She was treated by further excision and received a total of four regimens of chemotherapy including a combination of doxorubicin and cyclophosphamide. She received chemotherapy for 20 months after the diagnosis of metastasis.


2010 ◽  
Vol 457 (3) ◽  
pp. 337-345 ◽  
Author(s):  
Natalia Buza ◽  
Nazila Zekry ◽  
Colette Charpin ◽  
Fattaneh A. Tavassoli

2007 ◽  
Vol 24 (6) ◽  
pp. 543-548 ◽  
Author(s):  
P.C. CHEN ◽  
C.-K. CHEN ◽  
A.D. NICASTRI ◽  
R.B. WAIT

2012 ◽  
Vol 51 (3) ◽  
pp. 198-203
Author(s):  
Makoto URANO ◽  
Maki FUJIWARA ◽  
Kouichi TANAKA ◽  
Satomi ITOH ◽  
Yutaka HIRASAWA ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document