scholarly journals Neuroleptic malignant syndrome in a patient with moderate intellectual disability treated with olanzapine: A case report

2021 ◽  
Author(s):  
Francesco Piacenza ◽  
Suet Kee Ong ◽  
Patrick O’Brien ◽  
Maurice Clancy
Author(s):  
Francesco Piacenza ◽  
Suet Kee Ong ◽  
Patrick O'Brien ◽  
Maurice Clancy

We report the case of a 31 years old woman with moderate Intellectual Disability (ID) and Bipolar Affective Disorder who developed Neuroleptic Malignant Syndrome (NMS) after being treated with Olanzapine. Following discontinuation of the Olanzapine, she made a rapid and full recovery.


2005 ◽  
Vol 22 (3) ◽  
pp. 107-112 ◽  
Author(s):  
Peter Leonard ◽  
Sean Shanahan ◽  
John Hillery

AbstractThe association between intellectual disability and offending is complex. Recent evidence would suggest that the received wisdom of intellectually disabled persons being more prone to offending is either incorrect or only tells part of the story. Those within the ‘borderline’ intellectual disability range may be more prone to committing sexual and criminal damage offences but those with an IQ less than 50 rarely offend.The offender with intellectual disability shares characteristics with his counterpart from the general population. As with the general population as a whole, offending in this group is often unreported and its recognition is complicated by issues of competence. The lack of validated forensic assessment schedules for this population poses a further challenge. Some general approaches to assessment in this population are discussed. This case report illustrates the difficulties of assessing and managing offending behaviour in an individual with moderate intellectual disability. The challenge of treating offenders with an intellectual disability is immense and requires specialist expertise. Managing such cases in a generic setting is inappropriate and the need for a forensic learning disability service in Ireland is highlighted.


2021 ◽  
Author(s):  
Annabel Folch ◽  
Daniel Gallo ◽  
Jordi Miró ◽  
Luis Salvador‐Carulla ◽  
Rafael Martínez‐Leal

1986 ◽  
Vol 31 (1) ◽  
pp. 66-69 ◽  
Author(s):  
Margaret Schibuk ◽  
Debbie Schachter

The authors present a case report in which an agitated response to antidepressants preceded the neuroleptic malignant syndrome (NMS). In a review of 64 cases of NMS in the literature, they found that 80% were described as agitated prior to the development of the syndrome. Polypharmacy was common. A review of the literature on theories of pathogenesis involving sympathetic amines other than dopamine is presented to explain this phenomena. It is suggested that these toxic reactions to medication can be interpreted as resulting from a relative NE/DA excess, in which antidepressants increase the numerator, while neuroleptics functionally decrease the denominator. It is recommended that where an agitated response to antidepressants is observed, neuroleptics should be used only with considerable caution.


2016 ◽  
Vol 33 (3) ◽  
pp. 142-149 ◽  
Author(s):  
Robert Pennington ◽  
Allison Flick ◽  
Kendra Smith-Wehr

In the current study, we examined the effects of response prompting strategies (i.e., constant time delay, system of least prompts) and frames on sentence writing for three participants, ages 7 to 12, with moderate intellectual disability. We used a concurrent multiple probe across behaviors design to evaluate the efficacy of the intervention package and posttest probes to assess generalized responding to untrained stimulation. During intervention, the teacher taught two students to construct sentences using selection-based software and another to generate handwritten responses across three different writing frames (i.e., I want _________, I see _____, The _____ is ______). Our findings suggest that the package was effective and produced variable levels of maintenance and generalized responding for all three participants.


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