ChemInform Abstract: QUANTITATIVE STRUCTURE-ACTIVITY RELATION OF ANTIMALARIAL AND DIHYDROFOLATE REDUCTASE INHIBITION BY QUINAZOLINES AND 5-SUBSTITUTED BENZYL-2,4-DIAMINOPYRIMIDINES

Quantitative structure-activity relation of reversible dihydrofolate reductase inhibitors. Diaminotriazines

10.1021/jm00253a001 ◽

1974 ◽

Vol 17 (7) ◽

pp. 661-667 ◽

Cited By ~ 17

Author(s):

Corwin Hansch ◽

Carlo Silipo

Keyword(s):

Dihydrofolate Reductase ◽

Quantitative Structure ◽

Reductase Inhibitors ◽

Structure Activity ◽

Dihydrofolate Reductase Inhibitors ◽

Quantitative structure-activity relation of antimalarial and dihydrofolate reductase inhibition by quinazolines and 5-substituted benzyl-2,4-diaminopyrimidines

10.1021/jm00211a020 ◽

1977 ◽

Vol 20 (1) ◽

pp. 96-102 ◽

Cited By ~ 31

Author(s):

Corwin Hansch ◽

James Y. Fukunaga ◽

Priscilla Y. C. Jow ◽

John B. Hynes

Keyword(s):

Dihydrofolate Reductase ◽

Quantitative Structure ◽

Structure Activity ◽

Correction: Identification of potential antimicrobials against Salmonella typhimurium and Listeria monocytogenes using Quantitative Structure-Activity Relation modeling

PLoS ONE ◽

10.1371/journal.pone.0193628 ◽

2018 ◽

Vol 13 (2) ◽

pp. e0193628

Author(s):

The PLOS ONE Staff

Keyword(s):

Listeria Monocytogenes ◽

Salmonella Typhimurium ◽

Quantitative Structure ◽

Structure Activity ◽

Quantitative structure-activity relationship of triazine-antifolate inhibition of Leishmania dihydrofolate reductase and cell growth

10.1021/jm00390a017 ◽

1987 ◽

Vol 30 (7) ◽

pp. 1218-1224 ◽

Cited By ~ 24

Author(s):

Raymond G. Booth ◽

Cynthia Dias Selassie ◽

Corwin Hansch ◽

Daniel V. Santi

Keyword(s):

Cell Growth ◽

Dihydrofolate Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

Relationship Of

Quantitative Structure−Activity Relationships of 2,4-Diamino-5-(2-X-benzyl)pyrimidines versus Bacterial and Avian Dihydrofolate Reductase†

Quantitative Structure Activity Relationships

10.1021/jm970776j ◽

1998 ◽

Vol 41 (22) ◽

pp. 4261-4272 ◽

Cited By ~ 13

Author(s):

Cynthia Dias Selassie ◽

Wei-Xi Gan ◽

Lara S. Kallander ◽

Teri E. Klein

Keyword(s):

Dihydrofolate Reductase ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

Applications of neural networks in quantitative structure-activity relationships of dihydrofolate reductase inhibitors

Dihydrofolate Reductase Inhibitors

10.1021/jm00113a022 ◽

1991 ◽

Vol 34 (9) ◽

pp. 2824-2836 ◽

Cited By ~ 201

Author(s):

T. A. Andrea ◽

Hooshmand Kalayeh

Keyword(s):

Neural Networks ◽

Dihydrofolate Reductase ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Reductase Inhibitors ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

ChemInform Abstract: INHIBITION OF HUMAN DIHYDROFOLATE REDUCTASE BY 4,6-DIAMINO-1,2-DIHYDRO-2,2-DIMETHYL-1-(SUBSTITUTED-PHENYL)-S-TRIAZINES. A QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP ANALYSIS

Chemischer Informationsdienst ◽

10.1002/chin.198429225 ◽

1984 ◽

Vol 15 (29) ◽

Author(s):

B. A. HATHAWAY ◽

Z. GUO ◽

C. HANSCH ◽

T. J. DELCAMP ◽

S. S. SUSTEN ◽

...

Keyword(s):

Dihydrofolate Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Relationship Analysis ◽

Structure Activity ◽

Human Dihydrofolate Reductase

Dihydrofolate Reductase Inhibitors

ChemInform Abstract: USE OF PHYSICOCHEMICAL PARAMETERS IN DISTANCE GEOMETRY AND RELATED THREE-DIMENSIONAL QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIPS: A DEMONSTRATION USING ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE INHIBITORS

Chemischer Informationsdienst ◽

10.1002/chin.198532378 ◽

1985 ◽

Vol 16 (32) ◽

Author(s):

A. K. GHOSE ◽

G. M. CRIPPEN

Keyword(s):

Escherichia Coli ◽

Dihydrofolate Reductase ◽

Physicochemical Parameters ◽

Distance Geometry ◽

Three Dimensional ◽

Quantitative Structure ◽

Reductase Inhibitors ◽

Structure Activity ◽

Quantitative Structure Activity Relationships ◽

Quantitative Structure Activity Relationship Study of 2,4,6-Trisubstituted-s-triazine Derivatives as Antimalarial Inhibitors of Plasmodium Falciparum Dihydrofolate Reductase

Chemical Biology & Drug Design ◽

10.1111/j.1747-0285.2010.01045.x ◽

2010 ◽

Vol 77 (1) ◽

pp. 57-62 ◽

Cited By ~ 16

Author(s):

Himanshu Ojha ◽

Pragya Gahlot ◽

Anjani K. Tiwari ◽

Mallika Pathak ◽

Rita Kakkar

Keyword(s):

Plasmodium Falciparum ◽

Dihydrofolate Reductase ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

Triazine Derivatives ◽

Relationship Study

On the structure selectivity problem in drug design. A comparative study of benzylpyrimidine inhibition of vertebrate and bacterial dihydrofolate reductase via molecular graphics and quantitative structure-activity relationships

Quantitative Structure Activity Relationships

10.1021/jm00128a035 ◽

1989 ◽

Vol 32 (8) ◽

pp. 1895-1905 ◽

Cited By ~ 25

Author(s):

Cynthia Dias Selassie ◽

Zhaoxia Fang ◽

Renli Li ◽

Corwin Hansch ◽

Gargi Debnath ◽

...

Keyword(s):

Drug Design ◽

Comparative Study ◽

Dihydrofolate Reductase ◽

Quantitative Structure ◽

Molecular Graphics ◽

Structure Activity Relationships ◽

Structure Activity ◽