ChemInform Abstract: ROLE OF RIGID ELECTROPHILIC CENTERS DURING REACTION OF CARBONYL AND ORGANOPHOSPHORUS COMPOUNDS. IV. WITTIG REACTION IN COMPOUNDS HAVING RIGID ELECTROPHILIC CENTERS BESIDES THE PHOSPHORUS ATOM

1978 ◽  
Vol 9 (36) ◽  
Author(s):  
L. V. NESTEROV ◽  
N. E. KREPYSHEVA ◽  
R. A. SABIROVA ◽  
G. N. LIPKINA
Keyword(s):  
Phosphorus Atom ◽  
Wittig Reaction ◽  
Organophosphorus Compounds

Asymmetric Synthesis of Organophosphorus Compounds using H-P reagents derived from Chiral Alcohols

2021 ◽  
Author(s):  
Tomasz K. Olszewski ◽  
Joseph Gbubele
Keyword(s):  
Asymmetric Synthesis ◽  
Phosphorus Atom ◽  
Organophosphorus Compounds ◽  
Chiral Alcohols

Chiral organophosphorus compounds, especially those containing C-stereogenic carbons in the proximity of the phosphorus atom, are known for their unique properties and have found wide applications that span from medicinal...

Mechanism of the Wittig reaction: the role of substituents at phosphorus

1988 ◽  
Vol 110 (12) ◽  
pp. 3948-3958 ◽  
Author(s):  
E. Vedejs ◽  
C. F. Marth
Keyword(s):  
Wittig Reaction

scholarly journals Antioxidants in Organophosphorus Compounds Poisoning

2013 ◽  
Vol 64 (1) ◽  
pp. 169-177 ◽  
Author(s):  
Syed M Nurulain ◽  
Peter Szegi ◽  
Kornèlia Tekes ◽  
Syed Nh Naqvi
Keyword(s):  
Organophosphorus Compounds ◽  
Substantial Evidence ◽  
Research Papers ◽  
Mortality And Morbidity ◽  
Adjunct Treatment ◽  
Organ Level ◽  
Survival Studies ◽  
Positive Effect ◽  
Rational Conclusion

Oxidative stress has recently been implicated as a factor in the mortality and morbidity induced by organophosphorus (OP) compound poisoning. An overwhelming number of research papers are based on studying at the cellular and organ level. Such studies have concluded that antioxidants can be used as an adjunct compound in the treatment of both chronic as well as acute OP poisoning. Still, the role of antioxidants in reducing the mortality and morbidity induced by OP compounds has scarcely been verified, as well as their role as adjunct treatment compounds for both structurally and functionally different OP compounds. The present review of the literature was undertaken to establish the role of antioxidants in survival studies following acute exposure to OP compounds. The review found no substantial evidence that antioxidants demonstrate any positive effect following extremely toxic poisoning. However, for a more comprehensive and rational conclusion, further research needs to be conducted.

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