ChemInform Abstract: Pyridonecarboxylic Acids as Antibacterial Agents. Part 7. Synthesis and Structure-Activity Relationship of Amino- and Hydroxyl-Substituted 7-Cycloalkyl and 7-Vinyl Derivatives of 1-Cyclopropyl-6-fluoro-4- quinolone-3-carboxylic Acid.

ChemInform ◽  
2010 ◽  
Vol 26 (23) ◽  
pp. no-no
Author(s):  
Y. TODO ◽  
J. NITTA ◽  
M. MIYAJIMA ◽  
Y. FUKUOKA ◽  
Y. IKEDA ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Antibacterial Agents ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Vinyl Derivatives ◽  
Relationship Of ◽  
Derivatives Of

Synthesis and structure–activity relationship of amidine derivatives of 3,4-ethylenedioxythiophene as novel antibacterial agents

2015 ◽  
Vol 90 ◽  
pp. 68-81 ◽  
Author(s):  
Ivana Stolić ◽  
Hana Čipčić Paljetak ◽  
Mihaela Perić ◽  
Mario Matijašić ◽  
Višnja Stepanić ◽  
...  
Keyword(s):  
Antibacterial Agents ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of ◽  
Derivatives Of

Synthesis of Hippospongic Acid A Analogues Designed for Investigating the Structure-Activity Relationship of its Biological Activity

2000 ◽  
Vol 53 (12) ◽  
pp. 909 ◽  
Author(s):  
Yoshikazu Hiraga ◽  
Mariko Ago ◽  
Munetaka Tokumasu ◽  
Ken Kaku ◽  
Katsuo Ohkata
Keyword(s):  
Biological Activity ◽  
Carboxylic Acid ◽  
Sea Urchin ◽  
Essential Feature ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Acid Moiety ◽  
Sea Urchin Embryos ◽  
Structure Activity ◽  
Relationship Of

Analogues of hippospongic acid A, which inhibit the gastrulation of sea urchin embryos, were synthesized. From a study on structure—activity relationships, the conjugated carboxylic acid moiety was found to be an essential feature for biological activity.

scholarly journals From in vitro to in cellulo: structure–activity relationship of (2-nitrophenyl)methanol derivatives as inhibitors of PqsD in Pseudomonas aeruginosa

2014 ◽  
Vol 12 (32) ◽  
pp. 6094-6104 ◽  
Author(s):  
Michael P. Storz ◽  
Giuseppe Allegretta ◽  
Benjamin Kirsch ◽  
Martin Empting ◽  
Rolf W. Hartmann
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Relationship Of ◽  
Derivatives Of

More than 60 derivatives of (2-nitrophenyl)methanol were synthesized and evaluated regarding their potency to inhibit PqsD. In vitro and in cellulo structure–activity relationships were derived.

Structure–activity relationship of boronic acid derivatives of tyropeptin: Proteasome inhibitors

2010 ◽  
Vol 20 (19) ◽  
pp. 5839-5842 ◽  
Author(s):  
Takumi Watanabe ◽  
Hikaru Abe ◽  
Isao Momose ◽  
Yoshikazu Takahashi ◽  
Daishiro Ikeda ◽  
...  
Keyword(s):  
Boronic Acid ◽  
Proteasome Inhibitors ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Boronic Acid Derivatives ◽  
Relationship Of ◽  
Derivatives Of
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