From in vitro to in cellulo: structure–activity relationship of (2-nitrophenyl)methanol derivatives as inhibitors of PqsD in Pseudomonas aeruginosa

More than 60 derivatives of (2-nitrophenyl)methanol were synthesized and evaluated regarding their potency to inhibit PqsD. In vitro and in cellulo structure–activity relationships were derived.

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Interaction of flavones with DNA in vitro: structure–activity relationships

RSC Advances ◽

10.1039/c5ra04505c ◽

2015 ◽

Vol 5 (42) ◽

pp. 33058-33066 ◽

Cited By ~ 15

Author(s):

Bao Tu ◽

Zhi-Feng Chen ◽

Zhi-Juan Liu ◽

Li-Yang Cheng ◽

Yan-Jun Hu

Keyword(s):

Drug Discovery ◽

Drug Design ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity Relationships ◽

Structure Activity ◽

Relationship Of ◽

Novel Drug

The structure–activity relationship of the different flavones has been investigated, which may meaningful for drug discovery, and novel drug design.

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STRUCTURE-ACTIVITY RELATIONSHIP OF VARIOUS ANALOGUES OF β-CORTICOTRROPHIN DETERMINED BY REFERENCE TO VARIOUS PARAMETERS IN VITRO AND IN VIVO

Acta Endocrinologica ◽

10.1530/acta.0.061s029 ◽

1969 ◽

Vol 61 (1_Suppl) ◽

pp. S29

Author(s):

Pierre A. Desaulles ◽

René Maier ◽

Matthys Staehelin

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of

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Structure–activity relationship of piperine and its synthetic amide analogs for therapeutic potential to prevent experimentally induced ER stress in vitro

Cell Stress and Chaperones ◽

10.1007/s12192-017-0786-9 ◽

2017 ◽

Vol 22 (3) ◽

pp. 417-428 ◽

Cited By ~ 3

Author(s):

Ayat S. Hammad ◽

Sreenithya Ravindran ◽

Ashraf Khalil ◽

Shankar Munusamy

Keyword(s):

Er Stress ◽

Therapeutic Potential ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of ◽

Experimentally Induced

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Structure-Activity Relationship of (1.RAR.3)-.BETA.-D-Glucans in the Induction of Cytokine Production from Macrophages, in Vitro.

Biological and Pharmaceutical Bulletin ◽

10.1248/bpb.18.1320 ◽

1995 ◽

Vol 18 (10) ◽

pp. 1320-1327 ◽

Cited By ~ 98

Author(s):

Mitsuhiro OKAZAKI ◽

Yoshiyuki ADACHI ◽

Naohito OHNO ◽

Toshiro YADOMAE

Keyword(s):

Cytokine Production ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of

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Discovery and Structure−Activity Relationship of Antagonists of B-Cell Lymphoma 2 Family Proteins with Chemopotentiation Activity in Vitro and in Vivo

Journal of Medicinal Chemistry ◽

10.1021/jm050754u ◽

2006 ◽

Vol 49 (3) ◽

pp. 1165-1181 ◽

Cited By ~ 94

Author(s):

Michael D. Wendt ◽

Wang Shen ◽

Aaron Kunzer ◽

William J. McClellan ◽

Milan Bruncko ◽

...

Keyword(s):

B Cell ◽

Cell Lymphoma ◽

B Cell Lymphoma ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of

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Structure–activity relationship of boronic acid derivatives of tyropeptin: Proteasome inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2010.07.122 ◽

2010 ◽

Vol 20 (19) ◽

pp. 5839-5842 ◽

Cited By ~ 13

Author(s):

Takumi Watanabe ◽

Hikaru Abe ◽

Isao Momose ◽

Yoshikazu Takahashi ◽

Daishiro Ikeda ◽

...

Keyword(s):

Boronic Acid ◽

Proteasome Inhibitors ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Boronic Acid Derivatives ◽

Relationship Of ◽

Derivatives Of

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In vitro structure–activity relationship of Re-cyclized octreotide analogues

Nuclear Medicine and Biology ◽

10.1016/j.nucmedbio.2010.03.008 ◽

2010 ◽

Vol 37 (5) ◽

pp. 527-537 ◽

Cited By ~ 4

Author(s):

Shorouk F. Dannoon ◽

Heather M. Bigott-Hennkens ◽

Lixin Ma ◽

Fabio Gallazzi ◽

Michael R. Lewis ◽

...

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Of

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Synthesis and In Vitro Antimicrobial Activity of Medicinally Important Novel N-alkyl, N-aryl and Urea Derivatives of 1-benzhydryl Piperizine: A Structure-Activity Relationship Study

Letters in Drug Design & Discovery ◽

10.2174/157018009787582570 ◽

2009 ◽

Vol 6 (2) ◽

pp. 146-154

Author(s):

Channapillekoppal Ananda Kumar ◽

Karunakara Murthy ◽

Marlinganadoddi Sadashiva ◽

Mallappanahally Vinaya ◽

Naraganahalli Thimmegowda ◽

...

Keyword(s):

Antimicrobial Activity ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Urea Derivatives ◽

In Vitro Antimicrobial Activity ◽

Structure Activity ◽

Relationship Study ◽

Derivatives Of

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In vitro study of frog (Rana ridibunda pallas) interrenal function by use of a simplified perifusion system VIII. Structure-activity relationship of synthetic ACTH fragments and γ-MSH

General and Comparative Endocrinology ◽

10.1016/0016-6480(86)90196-6 ◽

1986 ◽

Vol 61 (2) ◽

pp. 187-196 ◽

Cited By ~ 13

Author(s):

F. Leboulenger ◽

I. Lihrmann ◽

P. Netchitailo ◽

C. Delarue ◽

I. Perroteau ◽

...

Keyword(s):

In Vitro Study ◽

Structure Activity Relationship ◽

Vitro Study ◽

Activity Relationship ◽

Rana Ridibunda ◽

Structure Activity ◽

Acth Fragments ◽

Relationship Of ◽

Perifusion System

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ChemInform Abstract: In vitro Antimicrobial Activity and Structure-Activity Relationship of C-2 Triazolylthio- and Pyridinylmethylthio-carbapenems (I).

ChemInform ◽

10.1002/chin.199632299 ◽

2010 ◽

Vol 27 (32) ◽

pp. no-no

Author(s):

C. FIAKPUI ◽

G. THOMAS ◽

M. P. SINGH ◽

R. G. MICETICH ◽

R. SINGH

Keyword(s):

Antimicrobial Activity ◽

Structure Activity Relationship ◽

Activity Relationship ◽

In Vitro Antimicrobial Activity ◽

Structure Activity ◽

Relationship Of

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