ChemInform Abstract: Synthesis of Side Chain Modified Apicidin Derivatives: Potent Mechanism-Based Histone Deacetylase Inhibitors

Peter T. Meinke; Steven L. Colletti; Michelle B. Ayer; Sandra J. Darkin-Rattray; Robert W. Myers; Dennis M. Schmatz; Matthew J. Wyvratt; Michael H. Fisher

doi:10.1002/chin.200052176

ChemInform Abstract: Synthesis of Side Chain Modified Apicidin Derivatives: Potent Mechanism-Based Histone Deacetylase Inhibitors

ChemInform ◽

10.1002/chin.200052176 ◽

2000 ◽

Vol 31 (52) ◽

pp. no-no

Author(s):

Peter T. Meinke ◽

Steven L. Colletti ◽

Michelle B. Ayer ◽

Sandra J. Darkin-Rattray ◽

Robert W. Myers ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Side Chain

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Synthesis of side chain modified apicidin derivatives: potent mechanism-based histone deacetylase inhibitors

Tetrahedron Letters ◽

10.1016/s0040-4039(00)01364-2 ◽

2000 ◽

Vol 41 (41) ◽

pp. 7831-7835 ◽

Cited By ~ 20

Author(s):

Peter T Meinke ◽

Steven L Colletti ◽

Michelle B Ayer ◽

Sandra J Darkin-Rattray ◽

Robert W Myers ◽

...

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Side Chain

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Design and Synthesis of Histone Deacetylase Inhibitors by Side Chain Modification of 2-Amino-(n-1)-alkenoic Acids

Understanding Biology Using Peptides ◽

10.1007/978-0-387-26575-9_161 ◽

2010 ◽

pp. 391-392

Author(s):

Mohammed P. I. Bhuiyan ◽

Tamaki Kato ◽

Norikazu Nishino

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Side Chain ◽

Design And Synthesis

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271: The Potential Clinical Application of Histone Deacetylase Inhibitors on Androgen Independent Prostate Cancer

The Journal of Urology ◽

10.1016/s0022-5347(18)32538-2 ◽

2006 ◽

Vol 175 (4S) ◽

pp. 90-90

Author(s):

Zhengwang Zhang ◽

Jennifer Stanfield ◽

Jer-Tsong Hsieh

Keyword(s):

Prostate Cancer ◽

Histone Deacetylase ◽

Clinical Application ◽

Histone Deacetylase Inhibitors ◽

Potential Clinical Application ◽

Androgen Independent

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Expression of different histone deacetylases and functional effects of histone deacetylase inhibitors in hepatocellular carcinoma

Zeitschrift für Gastroenterologie ◽

10.1055/s-0037-1612774 ◽

2018 ◽

Vol 56 (01) ◽

pp. E2-E89

Author(s):

P Dietrich ◽

K Freese ◽

W Thasler ◽

C Hellerbrand

Keyword(s):

Hepatocellular Carcinoma ◽

Histone Deacetylase ◽

Histone Deacetylases ◽

Histone Deacetylase Inhibitors

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2074-P: Histone Deacetylase Inhibitors Improve Store-Operated Calcium Entry and Glucose-Stimulated Insulin Secretion in Cytokine-Stressed Pancreatic ß-Cells

Diabetes ◽

10.2337/db20-2074-p ◽

2020 ◽

Vol 69 (Supplement 1) ◽

pp. 2074-P

Author(s):

CHIH-CHUN LEE ◽

TATSUYOSHI KONO ◽

STACI A. WEAVER ◽

PAUL SOHN ◽

CARMELLA EVANS-MOLINA

Keyword(s):

Insulin Secretion ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Calcium Entry ◽

Store Operated Calcium Entry ◽

Glucose Stimulated Insulin Secretion

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Faculty Opinions recommendation of Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1002037.18958 ◽

2001 ◽

Author(s):

Roger Hardie

Keyword(s):

Histone Deacetylase ◽

Histone Deacetylase Inhibitors

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Faculty Opinions recommendation of Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1012821.187300 ◽

2003 ◽

Author(s):

Albert La Spada

Keyword(s):

Histone Deacetylase ◽

Neuronal Death ◽

Histone Deacetylase Inhibitors ◽

Dependent Pathway

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Faculty Opinions recommendation of A functional genetic screen identifies retinoic acid signaling as a target of histone deacetylase inhibitors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1097071.553043 ◽

2007 ◽

Author(s):

Ted Abel

Keyword(s):

Retinoic Acid ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitors ◽

Genetic Screen ◽

Retinoic Acid Signaling

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Faculty Opinions recommendation of Application of the histone deacetylase inhibitors for the treatment of endometriosis: histone modifications as pathogenesis and novel therapeutic target.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.12224958.13400060 ◽

2011 ◽

Author(s):

Ricardo Buquet ◽

Edgardo Rolla

Keyword(s):

Histone Deacetylase ◽

Histone Modifications ◽

Therapeutic Target ◽

Histone Deacetylase Inhibitors ◽

Novel Therapeutic

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Faculty Opinions recommendation of Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13360101.14730261 ◽

2011 ◽

Author(s):

Jaap van Laar ◽

Steven O'Reilly

Keyword(s):

Rheumatoid Arthritis ◽

Histone Deacetylase ◽

Mrna Decay ◽

Histone Deacetylase Inhibitors

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