Mild and Nonracemizing Conditions for Ullmann-Type Diaryl Ether Formation Between Aryl Iodides and Tyrosine Derivatives.

Herein, we describe our initial development of an asymmetric Pd-catalyzed annulation between aryl iodides and racemic epoxides for synthesis of 2,3-dihydrobenzofurans using a chiral norbornene cocatalyst. A series of enantiopure ester-, amide- and imide-substituted norbornenes have been prepared with a reliable synthetic route. Promising enantioselectivity (42-45% ee) has been observed using the isopropyl ester-substituted norbornene (N1*) and the amide-substituted norbornene (N7*).

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A highly efficient heterogeneous copper-catalysed cascade reaction of aryl iodides with acetamidine hydrochloride leading to primary arylamines_esi

Journal of Chemical Research ◽

10.3184/174751917x14980525963196 ◽

2017 ◽

Keyword(s):

Cascade Reaction ◽

Highly Efficient ◽

Aryl Iodides

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Faculty Opinions recommendation of Site-specific incorporation of glycosylated serine and tyrosine derivatives into proteins.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1083797.536722 ◽

2007 ◽

Author(s):

Fritz Eckstein

Keyword(s):

Site Specific ◽

Tyrosine Derivatives

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Structural and Bioactive Studies of Halogenated Constituents from Sponges

Current Medicinal Chemistry ◽

10.2174/0929867325666181112092159 ◽

2020 ◽

Vol 27 (14) ◽

pp. 2335-2360 ◽

Cited By ~ 2

Author(s):

Chao Li ◽

Dayong Shi

Keyword(s):

Microbial Communities ◽

Organic Compounds ◽

Biological Activities ◽

Marine Sponges ◽

Nitrogen Compounds ◽

Halogenated Organic Compounds ◽

Bioactive Natural Products ◽

The Past ◽

Tyrosine Derivatives ◽

Polyunsaturated Lipids

: Marine organisms are abundant sources of bioactive natural products. Among metabolites produced by sponges and their associated microbial communities, halogenated natural compounds accounted for an important part due to their potent biological activities. The present review updates and compiles a total of 258 halogenated organic compounds isolated in the past three decades, especially brominated derivatives derived from 31 genera of marine sponges. These compounds can be classified as the following classes: brominated polyunsaturated lipids, nitrogen compounds, brominated tyrosine derivatives and other halogenated compounds. These substances were listed together with their source organisms, structures and bioactivities. For this purpose, 84 references were consulted.

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