ChemInform Abstract: Synthesis and Functional Analysis of the Key Compounds Responsible for Signal Transduction

ChemInform ◽  
2008 ◽  
Vol 39 (22) ◽  
Author(s):  
Yukari Fujimoto
Keyword(s):  
Signal Transduction ◽  
Functional Analysis

scholarly journals Functional Analysis of Ligand-Binding and Signal Transduction Domains of CD69 and CD23 C-Type Lectin Leukocyte Receptors

2000 ◽  
Vol 165 (7) ◽  
pp. 3868-3875 ◽  
Author(s):  
David Sancho ◽  
Ana G. Santis ◽  
José L. Alonso-Lebrero ◽  
Fernando Viedma ◽  
Reyes Tejedor ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Functional Analysis ◽  
Ligand Binding ◽  
Leukocyte Receptors

Functional analysis of CD82 in the early phase of T cell activation: roles in cell adhesion and signal transduction

1998 ◽  
Vol 28 (4) ◽  
pp. 1125-1133 ◽  
Author(s):  
Naotaka Shibagaki ◽  
Ken-ichi Hanada ◽  
Satoshi Yamaguchi ◽  
Hironori Yamashita ◽  
Shinji Shimada ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Functional Analysis ◽  
Cell Adhesion ◽  
T Cell ◽  
T Cell Activation ◽  
Early Phase ◽  
Cell Activation

scholarly journals Functional analysis of the ABA-responsive protein family in ABA and stress signal transduction in Arabidopsis

2013 ◽  
Vol 58 (31) ◽  
pp. 3721-3730 ◽  
Author(s):  
LingYun Liu ◽  
Na Li ◽  
ChunPeng Yao ◽  
SaSa Meng ◽  
ChunPeng Song
Keyword(s):  
Signal Transduction ◽  
Functional Analysis ◽  
Protein Family ◽  
Stress Signal

scholarly journals Functional analysis of EID1, an F-box protein involved in phytochrome A-dependent light signal transduction

2006 ◽  
Vol 45 (3) ◽  
pp. 423-438 ◽  
Author(s):  
Katia Marrocco ◽  
Yongchun Zhou ◽  
Erik Bury ◽  
Monika Dieterle ◽  
Markus Funk ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Functional Analysis ◽  
Light Signal ◽  
Phytochrome A ◽  
Light Signal Transduction ◽  
F Box Protein

scholarly journals PhosR enables processing and functional analysis of phosphoproteomic data

2020 ◽  
Author(s):  
Hani Jieun Kim ◽  
Taiyun Kim ◽  
Nolan J Hoffman ◽  
Di Xiao ◽  
David E James ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Signal Transduction ◽  
Functional Analysis ◽  
Global Scale ◽  
Comprehensive Analysis ◽  
Signalling Pathways ◽  
Biological Knowledge ◽  
Data Imputation ◽  
Collective Actions ◽  
R Packages

SUMMARYMass spectrometry (MS)-based phosphoproteomics has revolutionised our ability to profile phosphorylation-based signalling in cells and tissues on a global scale. To infer the action of kinases and signalling pathways in phosphoproteomic experiments, we present PhosR, a set of tools and methodologies implemented in a suite of R packages facilitating comprehensive analysis of phosphoproteomic data. By applying PhosR to both published and new phosphoproteomic datasets, we demonstrate capabilities in data imputation and normalisation using a novel set of ‘stably phosphorylated sites’, and in functional analysis for inferring active kinases and signalling pathways. In particular, we introduce a ‘signalome’ construction method for identifying a collection of signalling modules to summarise and visualise the interaction of kinases and their collective actions on signal transduction. Together, our data and findings demonstrate the utility of PhosR in processing and generating novel biological knowledge from MS-based phosphoproteomic data.

Phosphoproteomics strategies for the functional analysis of signal transduction

PROTEOMICS ◽  
2006 ◽  
Vol 6 (14) ◽  
pp. 4047-4056 ◽  
Author(s):  
Sandra Morandell ◽  
Taras Stasyk ◽  
Karin Grosstessner-Hain ◽  
Elisabeth Roitinger ◽  
Karl Mechtler ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Functional Analysis

Functional analysis of cotton orthologs of GA signal transduction factors GID1 and SLR1

2008 ◽  
Vol 68 (1-2) ◽  
pp. 1-16 ◽  
Author(s):  
Lorenzo Aleman ◽  
Jun Kitamura ◽  
Haggag Abdel-mageed ◽  
Joohyun Lee ◽  
Yan Sun ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Functional Analysis
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