A validated enantiospecific method for determination and purity assay of clopridogrel

Chirality ◽  
2009 ◽  
Vol 21 (10) ◽  
pp. 878-885 ◽  
Author(s):  
Katarina Nikolic ◽  
Branka Ivković ◽  
Željka Bešović ◽  
Slavko Marković ◽  
Danica Agbaba
Keyword(s):  
Purity Assay

Seeing through Macromolecules:T2-Filtered NMR for the Purity Assay of Functionalized Nanosystems and the Screening of Biofluids

2009 ◽  
Vol 131 (40) ◽  
pp. 14222-14224 ◽  
Author(s):  
Federico Rastrelli ◽  
Satadru Jha ◽  
Fabrizio Mancin
Keyword(s):  
Purity Assay

HPLC direct purity assay using ultra-purified materials as primary standards

2010 ◽  
Vol 398 (7-8) ◽  
pp. 3183-3192 ◽  
Author(s):  
Thierry Le Goff ◽  
Elodie Champarnaud ◽  
Fahmina Fardus
Keyword(s):  
Purity Assay ◽  
Primary Standards

scholarly journals Correction to Importance of Purity Evaluation and the Potential of Quantitative 1H NMR as a Purity Assay

2015 ◽  
Vol 58 (22) ◽  
pp. 9061-9061
Author(s):  
Guido F. Pauli ◽  
Shao-Nong Chen ◽  
Charlotte Simmler ◽  
David C. Lankin ◽  
Tanja Gödecke ◽  
...  
Keyword(s):  
1H Nmr ◽  
Purity Evaluation ◽  
Purity Assay

scholarly journals Identification of Microcystin-RR and [Dha7]Microcystin-RR in Commercial Standards by Electrospray Ionization Mass Spectrometry

2004 ◽  
Vol 87 (4) ◽  
pp. 1028-1031 ◽  
Author(s):  
Cariton Kubwabo ◽  
Natalia Vais ◽  
Frank M Benoit
Keyword(s):  
Mass Spectrometry ◽  
Electrospray Ionization ◽  
Electrospray Ionization Mass Spectrometry ◽  
Mass Spectra ◽  
Ionization Mass Spectrometry ◽  
Array Detector ◽  
Ionization Mass ◽  
Photodiode Array Detector ◽  
Photodiode Array ◽  
Purity Assay

Abstract Three different commercial standards of microcystin-RR were assessed for purity by the liquid chromatography coupled with electrospray ionization mass spectrometry (LC/ESI/MS) technique. Although the liquid chromatograms with photodiode array detector for each standard looked virtually identical, the analysis of corresponding mass spectra revealed that only one of them contained microcystin-RR per purity assay. The second standard was a mixture of microcystin-RR, and its demethyl variant identified as [Dha7]microcystin-RR, and the third one contained [Dha7]microcystin-RR only. We strongly recommend applying LC coupled with MS for purity assay of microcystin standards.

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