A 3-Armed Randomized Controlled Trial of Nurses’ Continuing Education Meetings on Adverse Drug Reactions

2015 ◽  
Vol 35 (2) ◽  
pp. 123-130 ◽  
Author(s):  
Amir Sarayani ◽  
Fahimeh Naderi-Behdani ◽  
Naser Hadavand ◽  
Mohammadreza Javadi ◽  
Fariborz Farsad ◽  
...  

Toxicon ◽  
2016 ◽  
Vol 120 ◽  
pp. 159-165 ◽  
Author(s):  
Senanayake A.M. Kularatne ◽  
Kosala Weerakoon ◽  
Anjana Silva ◽  
Kalana Maduwage ◽  
Chamara Walathara ◽  
...  


2021 ◽  
Vol 14 (10) ◽  
pp. 1056
Author(s):  
Katja S. Just ◽  
Catharina Scholl ◽  
Miriam Boehme ◽  
Kathrin Kastenmüller ◽  
Johannes M. Just ◽  
...  

The aim of this study was to compare effects of an individualized with a standardized risk assessment for adverse drug reactions to improve drug treatment with antithrombotic drugs in older adults. A randomized controlled trial was conducted in general practitioner (GP) offices. Patients aged 60 years and older, multi-morbid, taking antithrombotic drugs and at least one additional drug continuously were randomized to individualized and standardized risk assessment groups. Patients were followed up for nine months. A composite endpoint defined as at least one bleeding, thromboembolic event or death reported via a trigger list was used. Odds ratios (OR) and 95% confidence intervals (CI) were calculated. In total, N = 340 patients were enrolled from 43 GP offices. Patients in the individualized risk assessment group met the composite endpoint more often than in the standardized group (OR 1.63 [95%CI 1.02-2.63]) with multiple adjustments. The OR was higher in patients on phenprocoumon treatment (OR 1.99 [95%CI 1.05-3.76]), and not significant on DOAC treatment (OR 1.52 [95%CI 0.63-3.69]). Pharmacogenenetic variants of CYP2C9, 2C19 and VKORC1 were not observed to be associated with the composite endpoint. The results of this study may indicate that the time point for implementing individualized risk assessments is of importance.









2020 ◽  
Author(s):  
Hui Min Lin ◽  
Sheng Bin Guo ◽  
Rong Fang Hu ◽  
Tao Hong Wu ◽  
Na Mei Xie

BACKGROUND Providing the birthing woman with freedom of position has very significant advantages over traditional supine posture. Unfortunately, the rate of free position is not satisfactory worldwide. In China, as the main provider, the lack of ability of midwives greatly restricts the use of position. While the mechanism of action of position is abstract and complex, virtual simulation technology may make it easier for midwives to master. OBJECTIVE This study aimed to explore the application effects of the blended teaching method in midwives continuing education by combining online learning with conventional lecturing. METHODS A parallel randomized controlled trial was conducted. A total of 41 midwives from a childbirth room were enrolled and randomly assigned to two groups. The midwives in the experimental group (n=21) received a training program using the blended learning method, and the midwives in the control group (n=20) received a traditional teaching method. Using the Kirkpatrick Model to evaluate the training effects from four levels (Reaction, Learning, Behavior, Results). RESULTS The satisfaction of the experimental group on teaching aids, learning atmosphere, and overall satisfaction was higher than that of the control group (P<0.05). The knowledge scores of both groups were significantly improved (P<0.001), and the experimental group’s knowledge and skill scores were higher than the control group (P<0.05). The scores of clarifying maternal position needs and guiding family members to cooperate with the mother significantly improved in the experimental group, which were higher than those in the control group. The rate of non-supine childbirth in the experimental group increased significantly (P=0.030). The rate of perineal incision in primiparas was lower than that in the control group (P=0.040), and it was lower than before training (P=0.035). CONCLUSIONS The blended learning can increase midwives' satisfaction with training conditions and training effects, better improve knowledge and skills, accelerate the positive change of attitude towards in free position, increase the rate of childbirth in non-supine position,and reduce the rate of perineal incision in primiparas.



Sign in / Sign up

Export Citation Format

Share Document