Spectroscopic Study on Interaction of Lomefloxacin with Human Serum Albumin in the Presence of Copper Ion

2007 ◽  
Vol 25 (11) ◽  
pp. 1675-1680 ◽  
Author(s):  
Fen JIN ◽  
Jian-Quan LÜ ◽  
Xing-Wang ZHOU ◽  
Ting-Quan SUN
2012 ◽  
Vol 2012 ◽  
pp. 1-4 ◽  
Author(s):  
G. Rezaei Behbehani ◽  
L. Barzegar ◽  
M. Mohebbian ◽  
A. A. Saboury

The interaction of Cu2+with the first 16 residues of the Alzheimer's amyliodβpeptide,Aβ(1–16), and human serum albumin (HSA) were studied in vitro by isothermal titration calorimetry at pH 7.2 and 310 K in aqueous solution. The solvation parameters recovered from the extended solvation model indicate that HSA is involved in the transport of copper ion. Complexes betweenAβ(1–16) and copper ions have been proposed to be an aberrant interaction in the development of Alzheimer's disease, where Cu2+is involved inAβ(1–16) aggregation. The indexes of stability indicate that HSA removed Cu2+fromAβ(1–16), rapidly, decreased Cu-induced aggregation ofAβ(1–16), and reduced the toxicity ofAβ(1–16) + Cu2+significantly.


FEBS Journal ◽  
2006 ◽  
Vol 273 (3) ◽  
pp. 451-467 ◽  
Author(s):  
H. G. Mahesha ◽  
Sridevi Annapurna Singh ◽  
N. Srinivasan ◽  
A. G. Appu Rao

2013 ◽  
Vol 08 (01n02) ◽  
pp. 101-101
Author(s):  
SAQER M. DARWISH ◽  
SAWSAN E. ABU SHARKH ◽  
MUSA M. ABU TEIR ◽  
SAMI A. MAKHARZA ◽  
MAHMOUD M. ABU HADID

Chemosphere ◽  
2013 ◽  
Vol 93 (6) ◽  
pp. 1125-1130 ◽  
Author(s):  
Wenjuan Lv ◽  
Yonglei Chen ◽  
Dayong Li ◽  
Xingguo Chen ◽  
Jerzy Leszczynski

2019 ◽  
Vol 1179 ◽  
pp. 685-693 ◽  
Author(s):  
Anukul Maji ◽  
Maidul Beg ◽  
Somnath Das ◽  
Gopal Chandra Jana ◽  
Pradeep K. Jha ◽  
...  

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