Methanesulfonic acid has been found to be a highly effective catalyst for a convenient and one-pot synthesis of 2-substituted benzoxazoles by the reaction of 2-aminophenol with acid chlorides, generated in situ from carboxylic acids. Aryl, heteroaryl, and arylalkyl carboxylic acids provided excellent yields of the corresponding benzoxazoles. The reaction conditions were compatible with various substituents such as chloro, bromo, nitro, methoxy, cyclopentyloxy, phenoxy, thiophenoxy, and conjugated double bonds. Benzoxazole formation was found to be general with respect to substituted 2-aminophenols.
An atom-efficient, wholly aqueous one-pot synthesis of zwitterionic diblock copolymers has been devised. Such copolymers can serve as highly effective aqueous dispersants for nano-sized transparent yellow iron oxide particles.
Al-SBA-15-TPI/H6P2W18O62 is introduced as an effective catalyst for the one-pot synthesis of indazolo-phthalazine-triones. The catalyst could be easily separated without noticeable reduction in activity.
ZnO nanoparticles as a worthwhile and recyclable catalyst have been used for the one-pot synthesis of 1,8-dioxo-decahydroacridines and 1,8-dioxooctahydro-xanthenes via multi-component reactions under solvent-free conditions. The presented method is mild, environmentally friendly, inexpensive and highly effective to give the products in good to excellent yields.
AbstractReadily prepared copper nanoparticles are an effective catalyst for 1,3-dipolar cycloaddition of carbohydrate azide and a variety of alkynes that furnishes the corresponding 1,2,3-triazole-sucrose derivatives in excellent yields. Products were screened for their antimycobacterial activity against
H7[(P2W17O61)FeIII(H2O)] is introduced as an effective catalyst for the one-pot synthesis ofN,N′-alkylidenebisamides. The catalyst could be easily separated without noticeable reduction in activity.
Aqueous one-pot synthesis of well-defined zwitterionic diblock copolymers by RAFT polymerization: an efficient and environmentally-friendly route to a useful dispersant for aqueous pigments