scholarly journals Transient manifestation of left ventricular diastolic dysfunction following ablation in patients with paroxysmal atrial fibrillation

2018 ◽  
Vol 41 (7) ◽  
pp. 978-984 ◽  
Author(s):  
Tomoko Minamisaka ◽  
Tetsuya Watanabe ◽  
Yukinori Shinoda ◽  
Kuniyasu Ikeoka ◽  
Hidetada Fukuoka ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Diastolic Dysfunction ◽  
Paroxysmal Atrial Fibrillation ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Ventricular Diastolic Dysfunction

scholarly journals Left ventricular diastolic dysfunction and N-terminal probrain sodium-uretic peptid level in patients with atrial fibrillation

2013 ◽  
Vol 18 (2) ◽  
pp. 17-25
Author(s):  
G. V. Dzyak ◽  
L. I. Vasylieva ◽  
L. V. Sapozhnychenko ◽  
O. S. Kalashnykova ◽  
N. P. Anosova ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Diastolic Dysfunction ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Ventricular Diastolic Dysfunction

Abstract 13979: Left Atrial Symmetry Changes in Atrial Fibrillation: Relation With Diastolic Dysfunction and Symptom Severity

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Sotirios Nedios ◽  
Ole-A. Breithardt ◽  
Emmanuel Koutalas ◽  
Jedrzej Kosiuk ◽  
Philipp Sommer ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Linear Regression ◽  
Mitral Regurgitation ◽  
Diastolic Dysfunction ◽  
Symptom Severity ◽  
Left Atrial ◽  
Pulmonary Veins ◽  
Left Ventricular Diastolic Dysfunction ◽  
Left Ventricular ◽  
Ventricular Diastolic Dysfunction

Introduction: Atrial fibrillation (AF) progression has been associated with asymmetric left atrial (LA) dilatation and left ventricular diastolic dysfunction (LVDD). LVDD has been also correlated with symptom severity. Hypothesis: Aim of this study was to test the hypothesis that the pattern of LA asymmetry is associated to LVDD and symptom severity. Methods: In 104 patients (58±10 years old, 69% male) referred for AF ablation, CT data were used to determine the LA volume (LAV) after exclusion of the appendage and the pulmonary veins (PVs). A cutting plane, between the PV ostia and the appendage and parallel to the posterior wall, divided LAV into anterior- (LA-A) and posterior-LA (LA-P) parts. The ratio LA-A/LAV was defined as asymmetry index (ASI). LVDD was evaluated according to current guidelines and symptom severity was quantified using the European Heart Rhythm Association score. Results: Univariate linear regression revealed that ASI is associated with LVDD, LAV and mitral regurgitation. ASI was higher in patients with LVDD (n=35, 62±5% vs. 59±6%, p=0.013) and in patients with mitral regurgitation (n=67, 61±6% vs. 58±5%, p=0.025) than those without. LAV increase was associated with an ASI increase (r=0.26, p=0.008). Multiple linear regression analysis revealed that LAV (β=0.211, 95% CI: 0.003-0.071, p=0.033) and LVDD (β=0.207, 95% CI: 0.167-5.011, p=0.036) were the only independent predictors of ASI increase (adjusted r2=0.92, F=6.2, p=0.003). Patients with moderate-severe AF symptoms (n=61) had higher ASI (61±6% vs. 58±5%, p=0.012) and higher prevalence of LVDD (43% vs. 21%, p=0.034) than those with mild symptoms. Conclusions: LA symmetry changes are associated with dilatation and left ventricular diastolic dysfunction and correlate with symptom severity in AF.

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