scholarly journals Time-Dependent Diaryl Ether Inhibitors of InhA: Structure-Activity Relationship Studies of Enzyme Inhibition, Antibacterial Activity, and in vivo Efficacy

ChemMedChem ◽  
2014 ◽  
Vol 9 (4) ◽  
pp. 776-791 ◽  
Author(s):  
Pan Pan ◽  
Susan E. Knudson ◽  
Gopal R. Bommineni ◽  
Huei-Jiun Li ◽  
Cheng-Tsung Lai ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Enzyme Inhibition ◽  
Structure Activity Relationship ◽  
Time Dependent ◽  
Activity Relationship ◽  
In Vivo Efficacy ◽  
Structure Activity ◽  
Diaryl Ether

scholarly journals Antifungal Spectrum, In Vivo Efficacy, and Structure–Activity Relationship of Ilicicolin H

2012 ◽  
Vol 3 (10) ◽  
pp. 814-817 ◽  
Author(s):  
Sheo B. Singh ◽  
Weiguo Liu ◽  
Xiaohua Li ◽  
Tom Chen ◽  
Ali Shafiee ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
In Vivo Efficacy ◽  
Structure Activity ◽  
Relationship Of

scholarly journals Synthetic studies of cystobactamids as antibiotics and bacterial imaging carriers lead to compounds with high in vivo efficacy

2020 ◽  
Vol 11 (5) ◽  
pp. 1316-1334
Author(s):  
Giambattista Testolin ◽  
Katarina Cirnski ◽  
Katharina Rox ◽  
Hans Prochnow ◽  
Verena Fetz ◽  
...  
Keyword(s):  
Natural Product ◽  
Antibacterial Activities ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
In Vivo Efficacy ◽  
Structure Activity ◽  
Imaging Probes ◽  
Synthetic Studies

Structure–activity relationship studies of the natural product cystobactamid at four different positions led to novel imaging probes and analogs with superior antibacterial activities and in vivo efficacy.

scholarly journals Design, structure–activity relationship and in vivo efficacy of piperazine analogues of fenarimol as inhibitors of Trypanosoma cruzi

2013 ◽  
Vol 21 (7) ◽  
pp. 1756-1763 ◽  
Author(s):  
Martine Keenan ◽  
Paul W. Alexander ◽  
Hugo Diao ◽  
Wayne M. Best ◽  
Andrea Khong ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
In Vivo Efficacy ◽  
Structure Activity ◽  
Design Structure

6‐Methyl‐7‑Aryl‐7‑Deazapurine Nucleosides as Anti‐Trypanosoma cruzi Agents: Structure‐Activity Relationship and in Vivo Efficacy

ChemMedChem ◽  
2021 ◽  
Author(s):  
Cai Lin ◽  
Ludmila Ferreira de Almeida Fiuza ◽  
Camila Cardoso Santos ◽  
Daniela Ferreira Nunes ◽  
Otacílio Cruz Moreira ◽  
...  
Keyword(s):  
Trypanosoma Cruzi ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
In Vivo Efficacy ◽  
Structure Activity

Structure−Activity Relationship of 2-[[(2-Pyridyl)methyl]thio]-1H- benzimidazoles as AntiHelicobacter pyloriAgents in Vitro and Evaluation of their in Vivo Efficacy

1998 ◽  
Vol 41 (11) ◽  
pp. 1777-1788 ◽  
Author(s):  
Thomas C. Kühler ◽  
Marianne Swanson ◽  
Vladimir Shcherbuchin ◽  
Håkan Larsson ◽  
Björn Mellgård ◽  
...  
Keyword(s):  
Structure Activity Relationship ◽  
Activity Relationship ◽  
In Vivo Efficacy ◽  
Structure Activity ◽  
Relationship Of

Review: Studies on the Synthesis of Quinolone Derivatives with Their Antibacterial Activity (Part 1)

2020 ◽  
Vol 24 (8) ◽  
pp. 817-854
Author(s):  
Anil Kumar ◽  
Nishtha Saxena ◽  
Arti Mehrotra ◽  
Nivedita Srivastava
Keyword(s):  
Antibacterial Activity ◽  
Antibacterial Properties ◽  
Structure Activity Relationship ◽  
New Drugs ◽  
Activity Relationship ◽  
Structure Activity ◽  
Medicinal Properties ◽  
Synthetic Routes ◽  
Quinolone Derivatives

Quinolone derivatives have attracted considerable attention due to their medicinal properties. This review covers many synthetic routes of quinolones preparation with their antibacterial properties. Detailed study with structure-activity relationship among quinolone derivatives will be helpful in designing new drugs in this field.

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