Enteropathy-associated intestinal T-cell lymphoma in cavitating mesenteric lymph node syndrome: Fine-needle aspiration contributes to the diagnosis

2014 ◽  
Vol 43 (2) ◽  
pp. 125-130 ◽  
Author(s):  
Joerg Schwock ◽  
Elizabeth M. Hyjek ◽  
Emina E. Torlakovic ◽  
William R. Geddie
2015 ◽  
Vol 10 (3) ◽  
Author(s):  
Rouslan Kotchetkov ◽  
Vishal Kukreti MD

Celiac disease (CD) is a common systemic disease, affecting about 1.0% of the population. Classical presentation includes malabsorption syndrome and deficiencies of macro-/micronutrients. Patients with undiagnosed CD may be referred to hematologists with different hematologic issues, including anemia, thrombocytosis, thrombocytopenia, leukopenia, venous thromboembolism, hyposplenism, and IgA deficiency. CD imposes an increased risk of various lymphomas, especially intestinal T- and B-cell lymphomas. Enteropathy-associated T-cell lymphoma (EATL) is a rare and aggressive disease with poor prognosis and often fatal complications. Here we present a case of EATL associated with cavitating mesenteric lymph node syndrome as a first manifestation of undiagnosed CD.


2009 ◽  
Vol 37 (9) ◽  
pp. 686-695 ◽  
Author(s):  
Karla K. Dunning ◽  
Kitsada Wudhikarn ◽  
Anthony-Osei Safo ◽  
Carol J. Holman ◽  
Robert W. McKenna ◽  
...  

1989 ◽  
Vol 91 (2) ◽  
pp. 120-131 ◽  
Author(s):  
Ruth L. Katz ◽  
Andrey Gritsman ◽  
Fernando Cabanillas ◽  
Christina V. Fanning ◽  
Roupen Dekmezian ◽  
...  

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Olivia M. B. McBride ◽  
Richard J. E. Skipworth ◽  
Derek Leitch ◽  
Satheesh Yalamarthi

Cavitating mesenteric lymph node syndrome (CMLNS) is a rare and poorly understood complication of coeliac disease (CD), with only 37 cases reported in the literature. CD is an immune-mediated enteropathy, with alterations seen in the small bowel architecture on exposure to ingested gluten. Those who fail to respond to a strict gluten-free diet are termed to have refractory coeliac disease (RCD). This is associated with serious complications such as enteropathy-associated T-cell lymphoma (EATL). We present the case of a 71-year-old female investigated for weight loss and a palpable intraabdominal mass. Abdominal computed tomographic (CT) scan showed multiple necrotic mesenteric lymph nodes. At operation, multiple cavitating mesenteric lymph nodes, containing milky fluid, were found. An incidental EATL was found at the terminal ileum, which was resected. The patient subsequently tested positive for CD. This is the second case report to document an association between CMLNS and EATL. This paper highlights the varied presentation of CD. In this case, the diagnosis of CD was made retrospectively after the complications were dealt with. This paper is followed by a review of relevant literature.


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