scholarly journals Cavitating Mesenteric Lymph Node Syndrome and Enteropathy-Associated T Cell Lymphoma as First Manifestation of Celiac Disease

2015 ◽  
Vol 10 (3) ◽  
Author(s):  
Rouslan Kotchetkov ◽  
Vishal Kukreti MD
Keyword(s):  
Celiac Disease ◽  
Lymph Node ◽  
T Cell ◽  
Mesenteric Lymph Node ◽  
Cell Lymphoma ◽  
Systemic Disease ◽  
T Cell Lymphoma ◽  
Mesenteric Lymph ◽  
Increased Risk ◽  
Lymph Node Syndrome

Celiac disease (CD) is a common systemic disease, affecting about 1.0% of the population. Classical presentation includes malabsorption syndrome and deficiencies of macro-/micronutrients. Patients with undiagnosed CD may be referred to hematologists with different hematologic issues, including anemia, thrombocytosis, thrombocytopenia, leukopenia, venous thromboembolism, hyposplenism, and IgA deficiency. CD imposes an increased risk of various lymphomas, especially intestinal T- and B-cell lymphomas. Enteropathy-associated T-cell lymphoma (EATL) is a rare and aggressive disease with poor prognosis and often fatal complications. Here we present a case of EATL associated with cavitating mesenteric lymph node syndrome as a first manifestation of undiagnosed CD.

scholarly journals Cavitating Mesenteric Lymph Node Syndrome in Association with Coeliac Disease and Enteropathy Associated T-Cell Lymphoma: A Case Report and Review of the Literature

2010 ◽  
Vol 2010 ◽  
pp. 1-4 ◽  
Author(s):  
Olivia M. B. McBride ◽  
Richard J. E. Skipworth ◽  
Derek Leitch ◽  
Satheesh Yalamarthi
Keyword(s):  
Case Report ◽  
Lymph Node ◽  
T Cell ◽  
Lymph Nodes ◽  
Coeliac Disease ◽  
Mesenteric Lymph Node ◽  
Cell Lymphoma ◽  
Mesenteric Lymph Nodes ◽  
Mesenteric Lymph ◽  
Lymph Node Syndrome

Cavitating mesenteric lymph node syndrome (CMLNS) is a rare and poorly understood complication of coeliac disease (CD), with only 37 cases reported in the literature. CD is an immune-mediated enteropathy, with alterations seen in the small bowel architecture on exposure to ingested gluten. Those who fail to respond to a strict gluten-free diet are termed to have refractory coeliac disease (RCD). This is associated with serious complications such as enteropathy-associated T-cell lymphoma (EATL). We present the case of a 71-year-old female investigated for weight loss and a palpable intraabdominal mass. Abdominal computed tomographic (CT) scan showed multiple necrotic mesenteric lymph nodes. At operation, multiple cavitating mesenteric lymph nodes, containing milky fluid, were found. An incidental EATL was found at the terminal ileum, which was resected. The patient subsequently tested positive for CD. This is the second case report to document an association between CMLNS and EATL. This paper highlights the varied presentation of CD. In this case, the diagnosis of CD was made retrospectively after the complications were dealt with. This paper is followed by a review of relevant literature.

scholarly journals Cavitating mesenteric lymph node syndrome: An uncommon complication of celiac disease

2017 ◽  
Vol 82 (4) ◽  
pp. 351-353
Author(s):  
D. Ruiz-Clavijo García ◽  
A. García de Galdiano Fernández ◽  
B. González de la Higuera Carnicer ◽  
I. Rubio-Marco ◽  
M. Mercado Gutiérrez
Keyword(s):  
Celiac Disease ◽  
Lymph Node ◽  
Mesenteric Lymph Node ◽  
Mesenteric Lymph ◽  
Lymph Node Syndrome ◽  
Uncommon Complication

scholarly journals Cavitating mesenteric lymph node syndrome: a rare complication of celiac disease

2011 ◽  
Vol 103 (12) ◽  
pp. 652-654 ◽  
Author(s):  
Joaquín Rodríguez-Sánchez ◽  
Francisco Martín-Dávila ◽  
Bartolomé López-Viedma ◽  
M.ª Dolores Galván-Fernández ◽  
María Alonso-Lablanca ◽  
...  
Keyword(s):  
Celiac Disease ◽  
Lymph Node ◽  
Mesenteric Lymph Node ◽  
Rare Complication ◽  
Mesenteric Lymph ◽  
Lymph Node Syndrome

scholarly journals Radiographically Negative, Asymptomatic, Sentinel Lymph Node Positive Cutaneous T-Cell Lymphoma in a 3-Year-Old Male: A Case Report

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Jeffrey Carson ◽  
Jiri Bedrnicek ◽  
Shahab Abdessalam
Keyword(s):  
Lymph Node ◽  
T Cell ◽  
Sentinel Lymph Node ◽  
Metastatic Disease ◽  
Cell Lymphoma ◽  
Systemic Disease ◽  
Specific Treatment ◽  
T Cell Lymphoma ◽  
Cutaneous T Cell Lymphoma ◽  
Node Positive

We present a case of a 3-year-old male originally diagnosed with a CD30+ anaplastic cutaneous T-cell lymphoma with no evidence of systemic disease after CT scan, PET scan, and bone marrow aspiration. Sentinel lymph node biopsy (SLNB) was performed as an additional step in the workup and showed microscopic disease. Current management/recommendations for cutaneous T-cell lymphoma do not include SLNB. Medical and surgical management of cutaneous malignancies is dramatically different for local versus advanced disease. Therefore adequate evaluation is necessary to properly stage patients for specific treatment. Such distinction in extent of disease suggests more extensive therapy including locoregional radiation and systemic chemotherapy versus local excision only. Two international case reports have described SLNB in cutaneous T-cell lymphoma with one demonstrating evidence of node positive microscopic disease despite a negative metastatic disease workup. This case is being presented as a novel case in a child with implications including lymphoscintigraphy and SLNB as a routine procedure for evaluation and staging of cutaneous T-cell lymphoma if the patient does not demonstrate evidence of metastatic disease on routine workup.

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