Comparing scraping cytology with touch imprint cytology and frozen section analysis in the intraoperative diagnosis of sentinel lymph node metastasis in breast cancer

2021 ◽  
Author(s):  
Maryam Mohammadnia Avval ◽  
Massood Hosseinzadeh ◽  
Zahra Farahi ◽  
Maryamsadat Mirtalebi
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Frozen Section ◽  
Imprint Cytology ◽  
Intraoperative Diagnosis ◽  
Node Metastasis ◽  
Touch Imprint Cytology ◽  
Frozen Section Analysis ◽  
Section Analysis

scholarly journals Imprint cytology versus frozen section analysis for intraoperative assessment of sentinel lymph node in breast cancer

2017 ◽  
Vol Volume 9 ◽  
pp. 325-330 ◽  
Author(s):  
Thalia Petropoulou ◽  
Antonia Kapoula ◽  
Aikaterini Mastoraki ◽  
Aikaterini Politi ◽  
Eleni Spanidou-Karvouni ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Frozen Section ◽  
Imprint Cytology ◽  
Intraoperative Assessment ◽  
Frozen Section Analysis ◽  
Section Analysis

Comparison of Frozen Section and Touch Imprint Cytology for Evaluation of Sentinel Lymph Node Metastasis in Breast Cancer

2004 ◽  
Vol 11 (8) ◽  
pp. 747-750 ◽  
Author(s):  
Tomohiko Aihara ◽  
Satoru Munakata ◽  
Hideo Morino ◽  
Yuichi Takatsuka
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Node Metastasis ◽  
Frozen Section ◽  
Sentinel Lymph Node Metastasis ◽  
Imprint Cytology ◽  
Node Metastasis ◽  
Touch Imprint Cytology

Scoring system for prediction of having three or more involved axillary nodes for breast cancer.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 1133-1133
Author(s):  
Soo Kyung Ahn ◽  
Ji sun Kim ◽  
Jee Man You ◽  
Hee-Chul Shin ◽  
Hyeong Gon Moon ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Scoring System ◽  
Frozen Section ◽  
Multivariate Logistic Regression ◽  
Axillary Nodes ◽  
Frozen Section Analysis ◽  
Preoperative Image ◽  
Section Analysis

1133 Background: Completion axillary lymph node dissection (ALND) is currently the standard of care in the event of a positive sentinel lymph node biopsy (SLNB). However, result from Z0011 indicate that women with a one or two involved axillary nodes and clinical T1-T2 tumors undergoing lumpectomy with radiation therapy followed by systemic therapy do not benefit from completion of ALND in terms of survival. The purpose of this study was to define possible predictors of having three or more involved axillary node to provide information for surgeons making decision about sparing intraoperative frozen section analysis of sentinel lymph node and completion ALND. Methods: We reviewed the records of 1215 patients with clinical T1-T2 invasive breast cancer. None of these patients were in situ cancer on initial gun biopsy nor received neoadjuvant chemotherapy. Factors associated with having three or more involved axillary nodes were evaluated by univariate and multivariate logistic regression analysis. Results: Among 1215 patients, 321 patients had three or more positive nodes. On a multivariate analysis, having three or more positive nodes was associated with primary tumor size by breast US, axillary LN grade according to cortical thickness by US, presence of axillary LN enlargement on chest CT and age. A scoring system to predict the probability of having three or more nodes based on patients’ data and preoperative image findings was developed from the multivariate logistic regression model. The area under the ROC curve was 0.827 (95% CI: 0.793-0.860), and negative predictive value was 90.2% for a score ≤2.7. Similar findings were observed for a validation dataset of 505 patients. Conclusions: Patients with a low probability of having three or more positive nodes can be identified from preoperative image finding. The scoring system developed will be helpful to surgeons making decision about sparing intraoperative frozen section analysis of sentinel lymph node and completion ALND.

Intraoperative Frozen Section Analysis of Sentinel Lymph Node in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy

2008 ◽  
Vol 15 (6) ◽  
pp. 1717-1722 ◽  
Author(s):  
Kenzo Shimazu ◽  
Yasuhiro Tamaki ◽  
Tetsuya Taguchi ◽  
Fumine Tsukamoto ◽  
Tsutomu Kasugai ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Neoadjuvant Chemotherapy ◽  
Cancer Patients ◽  
Frozen Section ◽  
Breast Cancer Patients ◽  
Intraoperative Frozen Section ◽  
Frozen Section Analysis ◽  
Section Analysis

scholarly journals A prospective study comparing touch imprint cytology, frozen section analysis, and rapid cytokeratin immunostain for intraoperative evaluation of axillary sentinel lymph nodes in breast cancer

Cancer ◽  
2009 ◽  
Vol 115 (7) ◽  
pp. 1555-1562 ◽  
Author(s):  
Savitri Krishnamurthy ◽  
Funda Meric-Bernstam ◽  
Anthony Lucci ◽  
Rosa F. Hwang ◽  
Henry M. Kuerer ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Nodes ◽  
Prospective Study ◽  
Frozen Section ◽  
Sentinel Lymph Nodes ◽  
Imprint Cytology ◽  
Touch Imprint Cytology ◽  
Frozen Section Analysis ◽  
A Prospective Study ◽  
Section Analysis

scholarly journals Intraoperative imprint cytology of sentinel lymph nodes in breast cancer patients: Comparation with frozen section

2020 ◽  
Vol 77 (2) ◽  
pp. 196-200
Author(s):  
Tatjana Ivkovic-Kapicl ◽  
Ferenc Vicko ◽  
Milana Panjkovic ◽  
Zoran Radovanovic ◽  
Tijana Vasiljevic ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Nodes ◽  
Cancer Patients ◽  
Frozen Section ◽  
Sentinel Lymph Nodes ◽  
Imprint Cytology ◽  
Breast Cancer Patients ◽  
Touch Imprint Cytology

Background/Aim. Sentinel lymph node (SLN) biopsy has been established as the standard of care for axillary staging in patients with invasive breast carcinoma and clinically negative lymph nodes. Intraoperative assessment of sentinel lymph nodes might be done by frozen section (FS), touch imprint cytology (TIC) and one step nucleic acid amplification. The aim of this study was to review our institution's results with SLN biopsy using TIC and FS technique as intraoperative diagnostic tool for breast cancer patients. Methods. SLNs from 101 patients were examined intraoperatively by frozen hematoxylin-eosin (H&E) stain and by touch imprint cytology. Results of TIC were compared with FS and permanent histology sections. Results. The total number of dissected SLNs was 163 with a mean of 1.6 (1?4) per patient. The permanent H&E identified 19 (19%) patients with a sentinel lymph node metastasis and 82 (81%) patients with tumor-free sentinel nodes. The sensitivity/ specificity rates were 73.7%/99.3%, respectively for TIC and 84.2%/100%, respectively for FS. Relevant positive/ negative predictive values were 93.3%/96.6%, respectively for TIC and 100%/97.9%, respectively for FS. Conclusion. Our experience with TIC and FS for the intraoperative evaluation of SLNs is similar to the findings from previously reported studies. We detected the high specificity for both methods, but TIC technique appeared to be less sensitive than FS in detecting SLN metastases in breast cancer patients. TIC could be recommended as reasonable alternative to frozen section due to its simplicity and low cost.

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