scholarly journals Heterochromatin protein 1 beta regulates neural and neural crest development by repressing pluripotency‐associated gene pou5f3.2/oct25 in Xenopus

2021 ◽  
Author(s):  
Chih‐Liang Tien ◽  
Saeid Mohammadparast ◽  
Chenbei Chang
Keyword(s):  
Neural Crest ◽  
Heterochromatin Protein 1 ◽  
Heterochromatin Protein ◽  
Neural Crest Development

The tu8 Mutation of Arabidopsis thaliana Encoding a Heterochromatin Protein 1 Homolog Causes Defects in the Induction of Secondary Metabolite Biosynthesis

Plant Biology ◽  
2005 ◽  
Vol 7 (4) ◽  
pp. 348-357 ◽  
Author(s):  
R. N. Bennett ◽  
T. Wenke ◽  
B. Freudenberg ◽  
F. A. Mellon ◽  
J. Ludwig-Müller
Keyword(s):  
Arabidopsis Thaliana ◽  
Secondary Metabolite ◽  
Heterochromatin Protein 1 ◽  
Heterochromatin Protein ◽  
Secondary Metabolite Biosynthesis

scholarly journals Regulating the function of Twist, an essential factor in neural crest development and tumor progression

2011 ◽  
Vol 356 (1) ◽  
pp. 260
Author(s):  
Rachel M. Lander ◽  
Kara Nordin ◽  
Carole LaBonne
Keyword(s):  
Neural Crest ◽  
Tumor Progression ◽  
Essential Factor ◽  
Neural Crest Development

scholarly journals The methyltransferase NSD3 regulates neural crest development

2011 ◽  
Vol 356 (1) ◽  
pp. 196
Author(s):  
Bridget Jacques-Fricke ◽  
Laura S. Gammill
Keyword(s):  
Neural Crest ◽  
Neural Crest Development

scholarly journals Functional Characterization of LIKE HETEROCHROMATIN PROTEIN 1 in the moss Physcomitrella patens : its conserved protein interactions in land plants

2018 ◽  
Author(s):  
Vimala Parihar ◽  
Deepshikha Arya ◽  
Akanksha Walia ◽  
Vidhi Tyagi ◽  
Meenakshi Dangwal ◽  
...  
Keyword(s):  
Protein Interactions ◽  
Physcomitrella Patens ◽  
Functional Characterization ◽  
Land Plants ◽  
Heterochromatin Protein 1 ◽  
Heterochromatin Protein

Zika virus induces abnormal cranial osteogenesis by negatively affecting cranial neural crest development

2019 ◽  
Vol 69 ◽  
pp. 176-189 ◽  
Author(s):  
Yuqi Yan ◽  
Xiao-tan Zhang ◽  
Guang Wang ◽  
Xin Cheng ◽  
Yu Yan ◽  
...  
Keyword(s):  
Neural Crest ◽  
Zika Virus ◽  
Cranial Neural Crest ◽  
Neural Crest Development

Heterochromatin Protein 1 Deleted Chromo Domain Decreases Gene Silencing of Transgene in Mouse

2006 ◽  
Vol 28 (6) ◽  
pp. 419-424 ◽  
Author(s):  
Feng-Tao Liu ◽  
Yan Zhang
Keyword(s):  
Gene Silencing ◽  
Heterochromatin Protein 1 ◽  
Heterochromatin Protein ◽  
Chromo Domain

scholarly journals Xenopus Nkx6.3 Is a Neural Plate Border Specifier Required for Neural Crest Development

PLoS ONE ◽  
2014 ◽  
Vol 9 (12) ◽  
pp. e115165 ◽  
Author(s):  
Zuming Zhang ◽  
Yu Shi ◽  
Shuhua Zhao ◽  
Jiejing Li ◽  
Chaocui Li ◽  
...  
Keyword(s):  
Neural Crest ◽  
Neural Plate ◽  
Neural Crest Development ◽  
Neural Plate Border

scholarly journals Bimodal function of chromatin remodeler Hmga1 in neural crest induction and Wnt-dependent emigration

eLife ◽  
2020 ◽  
Vol 9 ◽  
Author(s):  
Shashank Gandhi ◽  
Erica J Hutchins ◽  
Krystyna Maruszko ◽  
Jong H Park ◽  
Matthew Thomson ◽  
...  
Keyword(s):  
Neural Crest ◽  
Neural Tube ◽  
Neural Crest Cells ◽  
Neural Plate ◽  
Chromatin Remodeler ◽  
Lineage Specification ◽  
Dorsal Neural Tube ◽  
Neural Crest Development ◽  
Neural Plate Border ◽  
Canonical Wnt

During gastrulation, neural crest cells are specified at the neural plate border, as characterized by Pax7 expression. Using single-cell RNA sequencing coupled with high-resolution in situ hybridization to identify novel transcriptional regulators, we show that chromatin remodeler Hmga1 is highly expressed prior to specification and maintained in migrating chick neural crest cells. Temporally controlled CRISPR-Cas9-mediated knockouts uncovered two distinct functions of Hmga1 in neural crest development. At the neural plate border, Hmga1 regulates Pax7-dependent neural crest lineage specification. At premigratory stages, a second role manifests where Hmga1 loss reduces cranial crest emigration from the dorsal neural tube independent of Pax7. Interestingly, this is rescued by stabilized ß-catenin, thus implicating Hmga1 as a canonical Wnt activator. Together, our results show that Hmga1 functions in a bimodal manner during neural crest development to regulate specification at the neural plate border, and subsequent emigration from the neural tube via canonical Wnt signaling.

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