Selectivity of the major histocompatibility complex class II presentation pathway of cortical thymic epithelial cell lines

1997 ◽  
Vol 27 (4) ◽  
pp. 855-859 ◽  
Author(s):  
Mohamed Oukka ◽  
Patrice Andre ◽  
Pascale Tunnel ◽  
Nelly Besnard ◽  
Veronique Angevin ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Epithelial Cell ◽  
Major Histocompatibility Complex Class ◽  
Cell Lines ◽  
Class Ii ◽  
Thymic Epithelial Cell ◽  
Complex Class ◽  
Histocompatibility Complex ◽  
Presentation Pathway ◽  
Epithelial Cell Lines

scholarly journals Delivery of a MalE CD4+-T-Cell Epitope into the Major Histocompatibility Complex Class II Antigen Presentation Pathway by Bordetella pertussis Adenylate Cyclase

2002 ◽  
Vol 70 (2) ◽  
pp. 1002-1005 ◽  
Author(s):  
Jir̆ina Loucká ◽  
Géraldine Schlecht ◽  
Jana Vodolánová ◽  
Claude Leclerc ◽  
Peter S̆ebo
Keyword(s):  
Major Histocompatibility Complex ◽  
T Cell ◽  
Adenylate Cyclase ◽  
Major Histocompatibility Complex Class ◽  
Class Ii ◽  
T Cell Response ◽  
Complex Class ◽  
Major Histocompatibility ◽  
Histocompatibility Complex ◽  
Presentation Pathway

ABSTRACT Recombinant adenylate cyclase toxoids are shown to deliver inserted foreign CD4+-T-cell epitopes into the major histocompatibility complex class II presentation pathway, inducing a specific CD4+-T-cell response in vivo and yielding in vitro stimulation of specific CD4+ T cells at a 100-times-higher molar efficiency than the free peptide containing the epitope.

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