Evaluation of a Yarrowia lipolytica Strain Collection for Its Lipid and Carotenoid Production Capabilities

2019 ◽  
Vol 122 (1) ◽  
pp. 1900172
Author(s):  
Stefan Bruder ◽  
Felix Arthur Melcher ◽  
Thomas Zoll ◽  
Silke Hackenschmidt ◽  
Johannes Kabisch
2014 ◽  
Vol 14 (4) ◽  
pp. 935-946 ◽  
Author(s):  
Anna Czech ◽  
Malwina Merska ◽  
Katarzyna Ognik

Abstract The aim of this study was to determine immunological and biochemical blood indicators of turkey hens administered feed mixtures with 3 or 6% of Yarrowia lipolytica strain yeast as a dietary nutrient. The experiment was carried out on 240 turkey hens, aged from 1 to 16 weeks. The hens were randomly assigned to 3 experimental groups of 80 birds. Group I served as a control (K) and did not receive any experimental compounds. The turkey hens from experimental groups (YL3, YL6) were administered dried Yarrowia lipolytica yeast in two doses: 3% (YL3) and 6% (YL6) in feed mixtures. The study showed that the addition of Yarrowia lipolytica yeast in a dose of 3% but mainly in a dose of 6% stimulated the body’s immune defence mechanisms, which was evidenced by the increase in plasma lysozyme, % KF, IF, and reduction of monocyte ratio H/L in turkey hens. The advantage of using Yarrowia lipolytica in the nutrition of turkey hens was also a decrease in the content of blood indicators of lipid peroxidation such as CHOL, TG and LDL-cholesterol fraction, and an increase in the percentage of HDL-cholesterol fraction. The use of yeast component in the feeding of turkey hens affected the health status of birds and contributed to proper (not deviating from the reference values) biochemical indicators of metabolism.


2017 ◽  
Vol 173 ◽  
pp. 592-599 ◽  
Author(s):  
Yao-Zu Han ◽  
Chao-Chao Zhou ◽  
Yan-Yan Xu ◽  
Jing-Xin Yao ◽  
Zhe Chi ◽  
...  

2020 ◽  
Vol 119 ◽  
pp. 306-316 ◽  
Author(s):  
Xiaoyan Liu ◽  
Xinjun Yu ◽  
Zhipeng Wang ◽  
Jun Xia ◽  
Yubo Yan ◽  
...  

2016 ◽  
Vol 9 (1) ◽  
Author(s):  
Jonathan Friedlander ◽  
Vasiliki Tsakraklides ◽  
Annapurna Kamineni ◽  
Emily H. Greenhagen ◽  
Andrew L. Consiglio ◽  
...  

2021 ◽  
Vol 9 (4) ◽  
pp. 838
Author(s):  
Macarena Larroude ◽  
Djamila Onésime ◽  
Olivier Rué ◽  
Jean-Marc Nicaud ◽  
Tristan Rossignol

The yeast Yarrowia lipolytica naturally produces pyomelanin. This pigment accumulates in the extracellular environment following the autoxidation and polymerization of homogentisic acid, a metabolite derived from aromatic amino acids. In this study, we used a chassis strain optimized to produce aromatic amino acids for the de novo overproduction of pyomelanin. The gene 4HPPD, which encodes an enzyme involved in homogentisic acid synthesis (4-hydroxyphenylpyruvic acid dioxygenase), was characterized and overexpressed in the chassis strain with up to three copies, leading to pyomelanin yields of 4.5 g/L. Homogentisic acid is derived from tyrosine. When engineered strains were grown in a phenylalanine-supplemented medium, pyomelanin production increased, revealing that the yeast could convert phenylalanine to tyrosine, or that the homogentisic acid pathway is strongly induced by phenylalanine.


2018 ◽  
Vol 265 ◽  
pp. 577-580 ◽  
Author(s):  
Peng Zhang ◽  
Zhi-Peng Wang ◽  
Jun Sheng ◽  
Yuan Zheng ◽  
Xiao-Feng Ji ◽  
...  

2015 ◽  
Vol 8 (1) ◽  
Author(s):  
Zhongpeng Guo ◽  
Sophie Duquesne ◽  
Sophie Bozonnet ◽  
Gianluca Cioci ◽  
Jean-Marc Nicaud ◽  
...  

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