A one-pot deracemization of β,γ-alkynyl α-amino esters consisting of an aerobic oxidation and chiral phosphoric acid-catalyzed asymmetric transfer hydrogenation has been described.
Chiral ruthenium/diamine-functionalized mesoporous silica is synthesized and its application in the one-pot synthesis of chiral β-hydroxy sulfones is investigated.
Pd(0)–Ru(iii)/diamine-functionalized periodic mesoporous organosilica for asymmetric transfer hydrogenation–Sonogashira coupling of iodoacetophenone and arynes is investigated.