Reactivities of quercetin and metallo‐quercetin with superoxide anion radical and molecular oxygen

In this work, the oxidation behaviour of phenol and chlorophenol contaminants present in the water catalyzed by histidine substituted nickel(II) phthalocyanine (NiPc) is reported. This work comprises synthesis, characterization and study the catalytic behaviour of histidine substituted NiPc on the oxidation of phenol and their substrates like 2- and 4-chlorophenols with 4-aminoantipyrine utilizing molecular oxygen. The products from the oxidation can be analyzed by UV-Vis spectroscopy and the results confirmed the formation of superoxide anion radical were crucial for the formation of product and a feasible mechanism including a successive transfer of single electron from phenolic compounds to O2 through the axis of histidine Ni(II)Pc was reported.

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Superoxide Anion Radical: Generation and Detection in Cellular and Non-Cellular Systems

Current Medicinal Chemistry ◽

10.2174/0929867322666151029104311 ◽

2015 ◽

Vol 22 (37) ◽

pp. 4234-4256 ◽

Cited By ~ 10

Author(s):

Renan Chiste ◽

Marisa Freitas ◽

Adriana Mercadante ◽

Eduarda Fernandes

Keyword(s):

Superoxide Anion ◽

Anion Radical ◽

Cellular Systems ◽

Superoxide Anion Radical ◽

Radical Generation

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Correction: Khorobrykh, A. Hydrogen Peroxide and Superoxide Anion Radical Photoproduction in PSII Preparations at Various Modifications of the Water-Oxidizing Complex. Plants 2019, 8, 329

Plants ◽

10.3390/plants10020187 ◽

2021 ◽

Vol 10 (2) ◽

pp. 187

Author(s):

Andrey Khorobrykh

Keyword(s):

Hydrogen Peroxide ◽

Superoxide Anion ◽

Anion Radical ◽

Superoxide Anion Radical ◽

Water Oxidizing Complex

In the original article, there was a mistake in the legend for ** Figure 5 ** [...]

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Effect of extraction conditions of paprika oleoresins on their free radical scavenging and anticancer activity

Open Chemistry ◽

10.2478/s11532-013-0378-1 ◽

2014 ◽

Vol 12 (3) ◽

pp. 377-385 ◽

Cited By ~ 4

Author(s):

Vesna Šaponjac ◽

Dragana Četojević-Simin ◽

Gordana Ćetković ◽

Jasna Čanadanović-Brunet ◽

Sonja Djilas ◽

...

Keyword(s):

Carbon Dioxide ◽

Supercritical Carbon Dioxide ◽

Cell Line ◽

Antiproliferative Activity ◽

Superoxide Anion ◽

Anion Radical ◽

Radical Scavenging ◽

Superoxide Anion Radical ◽

Food Ingredients ◽

Supercritical Carbon

AbstractGround spice paprika was extracted with hexane, by conventional Soxhlet procedure (SX oleoresin), and with supercritical carbon dioxide at three different pressures — 20, 30 and 40 MPa (SF20, SF30 and SF40 oleoresins). The effect of extraction method and conditions on the colour intesity of paprika oleoresins, content of α-tocopherol, as well as antioxidant and antiproliferative activity was examined. Hexane showed highest selectivity for paprika pigments (886.02 ASTA), while α-tocopherol showed highest solubility (3846.9 mg kg−1) in supercritical carbon dioxide at 20 MPa. All paprika oleoresins exhibited good superoxide anion radical scavenging activity SF30 being the best superoxide anion radical scavenger. Cell growth activity was evaluated in vitro in human cell lines:cervix epitheloid carcinoma (HeLa), breast adenocarcinoma (MCF7) and colon adenocarcinoma (HT-29). The highest antiproliferative activity was exhibited by SX in MCF7 cell line (IC50=14.28 mg mL−1). Extract SF40 produced significant and selective antiproliferative action towards HeLa cell line. These results suggest that paprika oleoresins, due to high antiradical and tumor cell-inhibiting activity, can be regarded as functional food ingredients.

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