scholarly journals Mitochondrial compromise in 3-year old patas monkeys exposedin uteroto human-equivalent antiretroviral therapies

2016 ◽  
Vol 57 (7) ◽  
pp. 526-534 ◽  
Author(s):  
Yongmin Liu ◽  
Eunwoo Shim Park ◽  
Alexander T. Gibbons ◽  
Eric D. Shide ◽  
Rao L. Divi ◽  
...  
Keyword(s):  
Patas Monkeys ◽  
Antiretroviral Therapies

Adhering to Antiretroviral Therapies

2001 ◽  
Vol 15 (3) ◽  
pp. 107-108 ◽  
Author(s):  
Jeffrey Laurence
Keyword(s):  
Antiretroviral Therapies

scholarly journals Locomotor Anatomy and Behavior of Patas Monkeys (Erythrocebus patas) with Comparison to Vervet Monkeys (Cercopithecus aethiops)

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Adrienne L. Zihlman ◽  
Carol E. Underwood
Keyword(s):  
Cercopithecus Aethiops ◽  
Whole Body ◽  
Relative Mass ◽  
Vervet Monkeys ◽  
Long Distance ◽  
Erythrocebus Patas ◽  
Locomotor System ◽  
Patas Monkeys ◽  
Foot Bones ◽  
Muscle Groups

Patas monkeys (Erythrocebus patas) living in African savanna woodlands and grassland habitats have a locomotor system that allows them to run fast, presumably to avoid predators. Long fore- and hindlimbs, long foot bones, short toes, and a digitigrade foot posture were proposed as anatomical correlates with speed. In addition to skeletal proportions, soft tissue and whole body proportions are important components of the locomotor system. To further distinguish patas anatomy from other Old World monkeys, a comparative study based on dissection of skin, muscle, and bone from complete individuals of patas and vervet monkeys (Cercopithecus aethiops) was undertaken. Analysis reveals that small adjustments in patas skeletal proportions, relative mass of limbs and tail, and specific muscle groups promote efficient sagittal limb motion. The ability to run fast is based on a locomotor system adapted for long distance walking. The patas’ larger home range and longer daily range than those of vervets give them access to highly dispersed, nutritious foods, water, and sleeping trees. Furthermore, patas monkeys have physiological adaptations that enable them to tolerate and dissipate heat. These features all contribute to the distinct adaptation that is the patas monkeys’ basis for survival in grassland and savanna woodland areas.

Cesarean Section for HIV-infected Women in the Combination Antiretroviral Therapies Era, 2000-2010

2014 ◽  
Vol 34 (3) ◽  
pp. 155
Author(s):  
N. Briand ◽  
C. Jasseron ◽  
J. Sibiude ◽  
E. Azria ◽  
J. Pollet ◽  
...  
Keyword(s):  
Cesarean Section ◽  
Antiretroviral Therapies

A reinterpretation of ‘sexual harassment’ in patas monkeys

1981 ◽  
Vol 29 (3) ◽  
pp. 957-958 ◽  
Author(s):  
Evan L. Zucker ◽  
Jay R. Kaplan
Keyword(s):  
Sexual Harassment ◽  
Patas Monkeys

scholarly journals Early initiation of highly active antiretroviral therapies for AIDS: Dynamic choice with endogenous and exogenous learning

2006 ◽  
Vol 25 (3) ◽  
pp. 579-598 ◽  
Author(s):  
Pierre Lasserre ◽  
Jean-Paul Moatti ◽  
Antoine Soubeyran
Keyword(s):  
Early Initiation ◽  
Dynamic Choice ◽  
Highly Active ◽  
Antiretroviral Therapies

The Systematic Development of Attributes And Levels For A Discrete Choice Experiment of HIV Patient Preferences For Long-Acting Antiretroviral Therapies In The United States

2021 ◽  
Author(s):  
Aaron T. Brah ◽  
Douglas Barthold ◽  
Brett Hauber ◽  
Ann C. Collier ◽  
Rodney J.Y. Ho ◽  
...  
Keyword(s):  
Discrete Choice Experiment ◽  
Discrete Choice ◽  
Patient Preferences ◽  
Choice Experiment ◽  
Treatment Time ◽  
Negative Reaction ◽  
Antiretroviral Therapies ◽  
Key Informant ◽  
Pre Treatment ◽  
Long Acting

Abstract Introduction: Patient preferences for long-acting antiretroviral therapies (LA-ART) should inform development of regimens with optimal adherence and acceptability. We describe a systematic process used to identify attributes and levels for a discrete choice experiment (DCE) designed to elicit preferences for potential LA-ART options in the US. Methods: Our approach was conducted in four stages: data collection, data reduction, removing inappropriate attributes, and optimizing wording. We started with 8 attributes defining potential LA-ART products based on existing literature and knowledge of products in development. We conducted 12 key informant interviews with experts in HIV treatment. The list of attributes, the set of plausible levels for each attribute, and restrictions on combinations of attribute levels were updated iteratively.Results: Despite uncertainty about which products will become available, key informant discussions converged on 4 delivery modes (infusions and patches were not considered immediately feasible) and 6 additional attributes. Treatment effectiveness and frequency of clinical monitoring were dropped. Oral lead-in therapy was split into two attributes: pre-treatment time undetectable and pre-treatment negative reaction testing. We omitted product-specific systemic and local side effects. In addition to mode, the final set of attributes included: frequency of dosing; location of treatment; pain; pre-treatment time undetectable; pre-treatment negative reaction testing; and late-dose leeway.Conclusions: A systematic process successfully captured elements that are both feasible and relevant to evaluating the acceptability of potential LA-ART alternatives to patients.

scholarly journals Who Wants to Switch? Gauging Patient Interest in Novel Antiretroviral Therapies

2018 ◽  
Vol 5 (10) ◽  
Author(s):  
Caroline B Derrick ◽  
Jan Ostermann ◽  
Sharon B Weissman ◽  
Amy Hobbie ◽  
Noor Alshareef ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Antiretroviral Therapies ◽  
Oral Regimen ◽  
Dosing Frequency ◽  
Study Participants ◽  
Novel Drug

Abstract Study participants were asked about their interest in switching to novel drug delivery systems that reduce the dosing frequency of antiretroviral regimens. Across a diverse, treatment-experienced cohort, we describe greatest interest in switching to an oral regimen taken once weekly, followed by injections taken every other month and twice-annual implants.

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