scholarly journals Functional architecture of the cortico-basal ganglia circuitry during motor task execution: Correlations of strength of functional connectivity with neuropsychological task performance among female subjects

2012 ◽  
Vol 34 (5) ◽  
pp. 1194-1207 ◽  
Author(s):  
William R. Marchand ◽  
James N. Lee ◽  
Yana Suchy ◽  
Cheryl Garn ◽  
Gordon Chelune ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Functional Connectivity ◽  
Task Performance ◽  
Motor Task ◽  
Task Execution ◽  
Functional Architecture ◽  
Female Subjects

Age-related changes of the functional architecture of the cortico-basal ganglia circuitry during motor task execution

NeuroImage ◽  
2011 ◽  
Vol 55 (1) ◽  
pp. 194-203 ◽  
Author(s):  
William R. Marchand ◽  
James N. Lee ◽  
Yana Suchy ◽  
Cheryl Garn ◽  
Susanna Johnson ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Motor Task ◽  
Task Execution ◽  
Functional Architecture ◽  
Age Related ◽  
Age Related Changes

scholarly journals Prior MDMA (Ecstasy) use is associated with increased basal ganglia–thalamocortical circuit activation during motor task performance in humans: An fMRI study

NeuroImage ◽  
2009 ◽  
Vol 46 (3) ◽  
pp. 817-826 ◽  
Author(s):  
John Karageorgiou ◽  
Mary S. Dietrich ◽  
Evonne J. Charboneau ◽  
Neil D. Woodward ◽  
Jennifer U. Blackford ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Task Performance ◽  
Motor Task ◽  
Fmri Study

scholarly journals The Influence of Aging on the Functional Connectivity of the Human Basal Ganglia

2022 ◽  
Vol 13 ◽  
Author(s):  
Clara Rodriguez-Sabate ◽  
Ingrid Morales ◽  
Manuel Rodriguez
Keyword(s):  
Basal Ganglia ◽  
Functional Connectivity ◽  
Closed Loop ◽  
Marked Effect ◽  
Motor Task ◽  
Young Group ◽  
Motor Tasks ◽  
Functional Interaction ◽  
Aged Group ◽  
Aged People

Although basal ganglia (BG) are involved in the motor disorders of aged people, the effect of aging on the functional interaction of BG is not well-known. This work was aimed at studying the influence of aging on the functional connectivity of the motor circuit of BG (BGmC). Thirty healthy volunteers were studied (young-group 26.4 ± 5.7 years old; aged-group 63.1 ± 5.8 years old) with a procedure planned to prevent the spurious functional connectivity induced by the closed-loop arrangement of the BGmC. BG showed different functional interactions during the inter-task intervals and when subjects did not perform any voluntary task. Aging induced marked changes in the functional connectivity of the BGmC during these inter-task intervals. The finger movements changed the functional connectivity of the BG, these modifications were also different in the aged-group. Taken together, these data show a marked effect of aging on the functional connectivity of the BGmC, and these effects may be at the basis of the motor handicaps of aged people during the execution of motor-tasks and when they are not performing any voluntary motor task.

Effects of Concurrent Manual Task Performance on Connected Speech Acoustics in Individuals With Parkinson Disease

2019 ◽  
Vol 62 (7) ◽  
pp. 2099-2117 ◽  
Author(s):  
Jason A. Whitfield ◽  
Zoe Kriegel ◽  
Adam M. Fullenkamp ◽  
Daryush D. Mehta
Keyword(s):  
Task Performance ◽  
Speech Production ◽  
Dual Task ◽  
Motor Task ◽  
Task Condition ◽  
Connected Speech ◽  
Speech Acoustics ◽  
Single Task ◽  
Manual Task ◽  
Task Conditions

Purpose Prior investigations suggest that simultaneous performance of more than 1 motor-oriented task may exacerbate speech motor deficits in individuals with Parkinson disease (PD). The purpose of the current investigation was to examine the extent to which performing a low-demand manual task affected the connected speech in individuals with and without PD. Method Individuals with PD and neurologically healthy controls performed speech tasks (reading and extemporaneous speech tasks) and an oscillatory manual task (a counterclockwise circle-drawing task) in isolation (single-task condition) and concurrently (dual-task condition). Results Relative to speech task performance, no changes in speech acoustics were observed for either group when the low-demand motor task was performed with the concurrent reading tasks. Speakers with PD exhibited a significant decrease in pause duration between the single-task (speech only) and dual-task conditions for the extemporaneous speech task, whereas control participants did not exhibit changes in any speech production variable between the single- and dual-task conditions. Conclusions Overall, there were little to no changes in speech production when a low-demand oscillatory motor task was performed with concurrent reading. For the extemporaneous task, however, individuals with PD exhibited significant changes when the speech and manual tasks were performed concurrently, a pattern that was not observed for control speakers. Supplemental Material https://doi.org/10.23641/asha.8637008

scholarly journals Strengthened Corticosubcortical Functional Connectivity during Muscle Fatigue

2016 ◽  
Vol 2016 ◽  
pp. 1-11 ◽  
Author(s):  
Zhiguo Jiang ◽  
Xiao-Feng Wang ◽  
Guang H. Yue
Keyword(s):  
Motor Control ◽  
Functional Connectivity ◽  
Quantile Regression ◽  
Muscle Fatigue ◽  
Motor Performance ◽  
Primary Motor Cortex ◽  
Motor Task ◽  
Voluntary Contraction ◽  
Control Network ◽  
Subcortical Structures

The present study examined functional connectivity (FC) between functional MRI (fMRI) signals of the primary motor cortex (M1) and each of the three subcortical neural structures, cerebellum (CB), basal ganglia (BG), and thalamus (TL), during muscle fatigue using the quantile regression technique. Understanding activation relation between the subcortical structures and the M1 during prolonged motor performance should help delineate how central motor control network modulates acute perturbations at peripheral sensorimotor system such as muscle fatigue. Ten healthy subjects participated in the study and completed a 20-minute intermittent handgrip motor task at 50% of their maximal voluntary contraction (MVC) level. Quantile regression analyses were carried out to compare the FC between the contralateral (left) M1 and CB, BG, and TL in the minimal (beginning 100 s) versus significant (ending 100 s) fatigue stages. Widespread, statistically significant increases in FC were found in bilateral BG, CB, and TL with the left M1 during significant versus minimal fatigue stages. Our results imply that these subcortical nuclei are critical components in the motor control network and actively involved in modulating voluntary muscle fatigue, possibly, by working together with the M1 to strengthen the descending central command to prolong the motor performance.

Operator orientation and compatibility in visual-motor task performance

Ergonomics ◽  
1989 ◽  
Vol 32 (4) ◽  
pp. 387-399 ◽  
Author(s):  
CHARLES J. WORRINGHAM ◽  
DENNIS B. BERINGER
Keyword(s):  
Task Performance ◽  
Motor Task ◽  
Visual Motor

scholarly journals Neuronal Substrates Underlying Performance Variability in Well-Trained Skillful Motor Task in Humans

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Nobuaki Mizuguchi ◽  
Shintaro Uehara ◽  
Satoshi Hirose ◽  
Shinji Yamamoto ◽  
Eiichi Naito
Keyword(s):  
Task Performance ◽  
Motor Skill ◽  
Brain Activity ◽  
Motor Task ◽  
Brain Regions ◽  
Anterior Cingulate ◽  
Cerebellar Hemisphere ◽  
Intensive Training ◽  
Performance Variability ◽  
The Right

Motor performance fluctuates trial by trial even in a well-trained motor skill. Here we show neural substrates underlying such behavioral fluctuation in humans. We first scanned brain activity with functional magnetic resonance imaging while healthy participants repeatedly performed a 10 s skillful sequential finger-tapping task. Before starting the experiment, the participants had completed intensive training. We evaluated task performance per trial (number of correct sequences in 10 s) and depicted brain regions where the activity changes in association with the fluctuation of the task performance across trials. We found that the activity in a broader range of frontoparietocerebellar network, including the bilateral dorsolateral prefrontal cortex (DLPFC), anterior cingulate and anterior insular cortices, and left cerebellar hemisphere, was negatively correlated with the task performance. We further showed in another transcranial direct current stimulation (tDCS) experiment that task performance deteriorated, when we applied anodal tDCS to the right DLPFC. These results indicate that fluctuation of brain activity in the nonmotor frontoparietocerebellar network may underlie trial-by-trial performance variability even in a well-trained motor skill, and its neuromodulation with tDCS may affect the task performance.

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