Lymph node density as an independent predictor of cancer-specific mortality in patients with lymph node-positive laryngeal squamous cell carcinoma after laryngectomy

Head & Neck ◽  
2014 ◽  
Vol 37 (9) ◽  
pp. 1319-1325 ◽  
Author(s):  
In Sun Ryu ◽  
Jong-Lyel Roh ◽  
Kyung-Ja Cho ◽  
Seung-Ho Choi ◽  
Soon Yuhl Nam ◽  
...  
2019 ◽  
Vol 276 (10) ◽  
pp. 2923-2927 ◽  
Author(s):  
Melih Cayonu ◽  
Evrim Unsal Tuna ◽  
Aydın Acar ◽  
Ayse Secil Kayalı Dinc ◽  
Muammer Melih Sahin ◽  
...  

2011 ◽  
Vol 18 (8) ◽  
pp. 2310-2317 ◽  
Author(s):  
Sang Yoon Kim ◽  
Soon Yuhl Nam ◽  
Seung-Ho Choi ◽  
Kyung-Ja Cho ◽  
Jong-Lyel Roh

2014 ◽  
Vol 3 (1) ◽  
pp. 20-23
Author(s):  
Esmael Amirazodi ◽  
Mahboobeh Razmkhah ◽  
Mansoureh Jaberipour ◽  
Ahmad Hosseini ◽  
Bijan Khademi

Background: Interleukin (IL)-4 is a member of T helper 2 (Th2) axis produced by T-lymphocyte and mast cell. It has been shown that IL-4 expression changes in tumor tissues. The main objective of this study is to investigate the expression of IL-4 mRNA in patients with Laryngeal Squamous Cell Carcinoma (LSCC) with or without lymph node involvement.Materials and Methods: mRNA expression of IL-4 in LSCC tissues were detected by quantative Real-Time PCR (qRT-PCR). Expression of IL-4 gene was compared between lymph node positive and negative patients with Squamous Cell Carcinoma of Larynx.Results: No statistically significant association was found in expression of IL-4 between lymph node positive and negative patients. Conclusion: It seems that IL-4 has no important effect on the involvement of lymph node in LSCC. However, to achieve a definite conclusion more investigations are certainly required.


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