scholarly journals Long-term follow-up of stereotactic radiosurgery for head and neck malignancies

Head & Neck ◽  
2014 ◽  
Vol 37 (11) ◽  
pp. 1557-1562 ◽  
Author(s):  
Dawn Owen ◽  
Fawaad Iqbal ◽  
Bruce E. Pollock ◽  
Michael J. Link ◽  
Kathy Stien ◽  
...  
2001 ◽  
Vol 19 (2) ◽  
pp. 127-136 ◽  
Author(s):  
John C. Grecula ◽  
David E. Schuller ◽  
Roy Smith ◽  
Chris A. Rhoades ◽  
Subir Nag ◽  
...  

2009 ◽  
Vol 140 (1) ◽  
pp. 120-123 ◽  
Author(s):  
Jae Chul Yoo ◽  
Youngjin Ahn ◽  
Yune Syung Lim ◽  
J. Hun Hah ◽  
Tack-Kyun Kwon ◽  
...  

2007 ◽  
Vol 18 (11) ◽  
pp. 1856-1860 ◽  
Author(s):  
P.M. Specenier ◽  
D. Van den Weyngaert ◽  
C. Van Laer ◽  
J. Weyler ◽  
J. Van den Brande ◽  
...  

2021 ◽  
Author(s):  
Ryosuke Matsuda ◽  
Takayuki Morimoto ◽  
Tetsuro Tamamoto ◽  
Nobuyoshi Inooka ◽  
Tomoko Ochi ◽  
...  

Abstract Purpose: This study aimed to assess the clinical outcomes of salvage surgical resection (SSR) after stereotactic radiosurgery and fractionated stereotactic radiotherapy (SRS/fSRT) for brain metastasis.Methods: Between November 2009 and December 2018, we treated 427 consecutive patients with 919 lesions with SRS/fSRT for newly diagnosed brain metastasis at our hospital. During the follow-up period, we treated 19 consecutive patients who underwent 21 SSRs for recurrence, radiation necrosis (RN), and cyst formation after SRS/fSRT for newly diagnosed brain metastasis. Two patients underwent multiple surgical resections. Brain metastasis originated from the lung (n=15, 78.9%), breast (n=3, 15.7%), and colon (n=1, 5.2%). Results: The median time from initial SRS/fSRT to SSR was 14 months (range: 2–96 months). The median follow-up after SSR was 15 months (range: 2–76 months). The range of tumor volume at initial SRS/SRT was 0.121–21.459 cm3 (median: 2.188 cm3). Histopathological diagnosis after SSR was recurrence, RN and cyst formation in 13 and 6 cases, respectively. The median survival time from SSR and from initial SRS/SRT was 17 months and 74 months, respectively. The cases with recurrence had a significantly shorter survival time than those without recurrence (p=0.0453).Conclusion: The patients treated with SRS/fSRT for brain metastasis need long-term follow-up. SSR is a safe and effective treatment for the recurrence, RN, and cyst formation after SRS/fSRT for brain metastasis.


1995 ◽  
Vol 31 ◽  
pp. S88-S89
Author(s):  
J.J. Grau ◽  
J. Estapé ◽  
J. Traserra ◽  
M. Galán ◽  
M. Daniels

Radiosurgery ◽  
2010 ◽  
pp. 202-211
Author(s):  
K. Sallabanda ◽  
J.C. Bustos ◽  
J.A. Gutiérrez-Díaz ◽  
C. Beltrán ◽  
C. Peraza ◽  
...  

2018 ◽  
Vol 114 ◽  
pp. e1192-e1198 ◽  
Author(s):  
Michel Lefranc ◽  
Leila Maria Da Roz ◽  
Anne Balossier ◽  
Jean Marc Thomassin ◽  
Pierre Hugue Roche ◽  
...  

Author(s):  
AM Wolf ◽  
K Naylor ◽  
D Kondziolka

Background: A major concern of patients undergoing Gamma Knife radiosurgery (GKS) for benign tumors and other conditions is the risk of a separate secondary malignancy or malignant -transformation. The incidence of radiosurgery-associated malignancy based on long-term follow-up remains unknown. Methods: We conducted a population-based cohort study to estimate the incidence rate of both malignant transformation and a separate radiation-associated malignancy in patients undergoing GKS from 1987 to 2016 at 5 centers. Results: 11 527 patients underwent radiosurgery for meningioma (n=3261), arteriovenous malformation (n=2868), trigeminal neuralgia (n=1982), vestibular schwannoma (n=1957), pituitary adenoma (n=1193), other (n=266). The follow-up time ranged from 0.3 to 23.8 years. Four cases of malignant transformation and 3 new malignant brain tumors were reported, two of which were not within the irradiated field. The incidence of malignant transformation was 6.6 per 100 000 patient-years and of new malignancy, either locally or distant, was 5 in 100 000 patient-years. These risks are not higher than the Central Brain Tumor Registry of the United States derived annual incidence rate of all primary malignant CNS tumors of 7.15 per 100 000. Conclusions: Physicians can safely counsel patients that the risk of malignancy after stereotactic radiosurgery remains extremely low, even at long-term follow-up of greater than 10 years.


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