Treatment outcomes of neoadjuvant chemotherapy and transoral robotic surgery in locoregionally advanced laryngopharyngeal carcinoma

Head & Neck ◽  
2021 ◽  
Author(s):  
Lorenzo S. Solimeno ◽  
Young Min Park ◽  
Jae‐Yol Lim ◽  
Yoon Woo Koh ◽  
Se‐Heon Kim

2019 ◽  
Vol 98 (03) ◽  
pp. 143-144
Author(s):  
Markus Kapsreiter

Karabulut B et al. Comparison of functional and oncological treatment outcomes after transoral robotic surgery and open surgery for supraglottic laryngeal cancer. J Laryngol Otol 2018; 132: 832–836 Die Behandlungsmöglichkeiten eines Supraglottiskarzinoms umfassen offene Supraglottis-Laryngektomie, transorale Lasertherapie, transorale Roboterchirurgie und Chemotherapie. Ärzte der HNO-Klinik des Ümraniye-Krankenhauses in Istanbul verglichen die Behandlungsergebnisse bei Patienten mit supraglottischen Tumoren des Larynxkarzinoms, die mittels einer transoralen robotischen Laryngektomie und einer offenen Laryngektomie behandelt wurden.



2013 ◽  
Vol 123 (3) ◽  
pp. 635-640 ◽  
Author(s):  
Harry Quon ◽  
Marc A. Cohen ◽  
Kathleen T. Montone ◽  
Amy F. Ziober ◽  
Li Ping Wang ◽  
...  


2018 ◽  
Vol 132 (9) ◽  
pp. 832-836 ◽  
Author(s):  
B Karabulut ◽  
İ Deveci ◽  
M Sürmeli ◽  
A Şahin-Yilmaz ◽  
Ç Oysu

AbstractObjectiveTo compare functional and oncological treatment outcomes among patients with supraglottic laryngeal cancers who underwent transoral robotic supraglottic laryngectomy and open supraglottic laryngectomy.MethodsA retrospective chart review was conducted of 17 patients treated by transoral robotic supraglottic laryngectomy and 20 patients treated by open supraglottic laryngectomy.ResultsNo tracheostomy or prolonged intubation was needed in the transoral robotic surgery group. Furthermore, that group had a shorter oral feeding time, hospitalisation and recovery period. There was no difference between groups in terms of complications. There were no differences in overall survival time and disease-specific survival time between groups.ConclusionTransoral robotic supraglottic laryngectomy for supraglottic laryngeal cancer is an oncologically safe and functional procedure with better results when compared to conventional open surgery.



2021 ◽  
pp. 019459982110574
Author(s):  
Esther Lee ◽  
Daniel Gorelik ◽  
Hannah R. Crowder ◽  
Christopher Badger ◽  
Jennifer Schottler ◽  
...  

Objective To evaluate 2-year follow-up swallowing function in patients with human papillomavirus–related oropharyngeal squamous cell carcinoma (HPV+ OPSCC) who completed neoadjuvant chemotherapy and transoral robotic surgery (NAC+S) Study Design Retrospective analysis of patients with OPSCC treated with NAC+S between 2010 and 2021. Setting A single academic institution. Methods This is a cross-sectional study of patient-reported swallowing function, assessed with the MD Anderson Dysphagia Inventory (MDADI) at least 2 years after completion of treatment. The inclusion criteria are patients with HPV+ OPSCC who underwent NAC+S at least 2 years ago. Those requiring adjuvant radiation or chemoradiation or experiencing relapse were excluded from the study. Results Completed MDADIs were received from 37 patients at a median 3.8 years posttreatment (interquartile range, 2.0-8.6 years). Of those, 94.6% (n = 35) were male and 81.1% (n = 30) were White. The median age at OPSCC diagnosis was 59.0 years (interquartile range, 41-80 years). The most frequent primary subsite of OPSCC was the base of the tongue (n = 20, 54.1%), followed by the tonsils (n = 16, 43.2%). In addition, 75.7% (n = 28) had stage IVa disease (TNM seventh edition), and 29 (78.4%) had scores ≥80, classified as optimal function. When compared with patients who received bilateral neck dissection, patients who received unilateral neck dissection were associated with an age <65 years old ( P = .036) and lower clinical TNM stage ( P = .04), as well as higher composite, emotional, functional, and physical MDADI scores ( P = .017, .046, .013, and .05, respectively). Conclusion Patients with OPSCC who were treated with NAC+S achieved satisfactory long-term swallowing outcomes. Unilateral neck dissection was significantly associated with higher MDADI scores in this patient cohort.





2017 ◽  
Vol 25 (4) ◽  
pp. 864-871 ◽  
Author(s):  
Young Min Park ◽  
Ki Chang Keum ◽  
Hye Ryun Kim ◽  
Byoung Chul Cho ◽  
Da Hee Kim ◽  
...  




2013 ◽  
Vol 74 (S 01) ◽  
Author(s):  
Christopher Rassekh ◽  
Shayanne Lajud ◽  
Courtney Shires ◽  
Laurie Loevner ◽  
Ara Chalian ◽  
...  


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