Selected functional outcomes in advanced oral cancer: Comparison of surgery alone versus surgery with postoperative radiotherapy

Head & Neck ◽  
2021 ◽  
Author(s):  
Ciaran Lane ◽  
Candace Myers ◽  
Deping Jiang ◽  
Andrew Cooke ◽  
Paul Kerr
Keyword(s):  
Oral Cancer ◽  
Functional Outcomes ◽  
Postoperative Radiotherapy

Impact of Postoperative Radiotherapy and Chemotherapy on Survival for Patients with Node Positive Oral Cancer

Health Care ◽  
2013 ◽  
Vol 1 (3) ◽  
pp. 89
Author(s):  
Mohamed Mahmoud ◽  
Tarek Souman ◽  
Mohamed Amin ◽  
Mona Aboelenin
Keyword(s):  
Oral Cancer ◽  
Postoperative Radiotherapy ◽  
Node Positive

Analysis of Speech and Functional Outcomes in Tongue Reconstruction after Hemiglossectomy

2020 ◽  
Vol 36 (07) ◽  
pp. 507-513
Author(s):  
Chang Ryul Yi ◽  
Woo Shik Jeong ◽  
Tae Suk Oh ◽  
Kyung S. Koh ◽  
Jong-Woo Choi
Keyword(s):  
Functional Outcome ◽  
Functional Outcomes ◽  
Speech Therapy ◽  
Tongue Cancer ◽  
Postoperative Radiotherapy ◽  
Postoperative Chemotherapy ◽  
Radiotherapy Group ◽  
Tongue Reconstruction ◽  
And Function ◽  
Tip Of The Tongue

Abstract Background Reconstruction in tongue cancer to restore the shape and function of the tongue without airway obstruction in the narrow oral cavity is challenging for reconstructive surgeons. Herein, the authors retrospectively analyzed flaps to reveal the factors that affect the functional outcome of tongue reconstruction. Methods Herein, we retrospectively reviewed 30 patients (men, 16; women, 14; mean age, 50.3 years) who underwent the hemi-tongue reconstruction followed by speech therapy between 2009 and 2017. Data about postoperative chemotherapy and radiotherapy were collected. The dimensions (width and length) of the flaps were measured. Speech outcomes were assessed under the conditions of varying distances of the tongue tip from lower incisors when it was protruded, retracted, and elevated. Lateralization was evaluated based on the count of teeth reached by the tip of the tongue from the midline. Results Preoperative chemotherapy and radiotherapy significantly influenced tongue retraction, tongue articulation, and intelligibility (p = 0.006, 0.002, 0.048, respectively). Postoperative chemotherapy did not statistically significantly influence any outcome measure. Contralateralization of the tongue was significantly decreased in the postoperative radiotherapy group (p = 0.029). The length of the flap showed highly negative correlation with articulation and intelligibility (p = 0.009, p< 0.001, respectively). The width of the flap was not correlated with the outcomes. Conclusion We proved that unlike chemotherapy, postoperative radiotherapy influences the functional outcome of tongue reconstruction. The dimensions, particularly the length of the flap, were also important for restoring the reconstructed tongue function.

Intraoperative Radiotherapy (IORT) with Low-Energy Photons as a Boost in Patients with Early-Stage Oral Cancer with the Indications for Postoperative Radiotherapy

2010 ◽  
Vol 186 (9) ◽  
pp. 496-501 ◽  
Author(s):  
Tomasz Rutkowski ◽  
Andrzej Wygoda ◽  
Marcin Hutnik ◽  
Krzysztof Składowski ◽  
Jerzy Wydmański ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Early Stage ◽  
Postoperative Radiotherapy ◽  
Intraoperative Radiotherapy ◽  
Low Energy

Trismus and reduced quality of life in patients with oral squamous cell carcinoma who received postoperative radiotherapy alone or combined with chemotherapy.

2017 ◽  
Vol 35 (31_suppl) ◽  
pp. 222-222 ◽  
Author(s):  
Ourania Nicolatou-Galitis ◽  
Amanda Psyrri
Keyword(s):  
Quality Of Life ◽  
Squamous Cell Carcinoma ◽  
Head And Neck Cancer ◽  
Oral Cancer ◽  
Oral Squamous Cell Carcinoma ◽  
Postoperative Radiotherapy ◽  
Mouth Opening ◽  
Financial Difficulties ◽  
C 30

222 Background: Patients, who receive radiotherapy (RT) for head and neck cancer, develop chronic functional abnormalities and reduced mouth opening-trismus, surviving with reduced quality of life (QoL). We aimed to study trismus and QoL in patients with oral cancer, who received post-operative radiotherapy or chemoradiotherapy. Methods: Patients, who receive radiotherapy (RT) for head and neck cancer, develop chronic functional abnormalities and reduced mouth opening-trismus, surviving with reduced quality of life (QoL). We aimed to study trismus and QoL in patients with oral cancer, who received post-operative radiotherapy or chemoradiotherapy. Results: Mean RT dose was 64.3 Gray. Six patients received chemoradiotherapy. Severe mucositis, pain and xerostomia were recorded in 6 and 5 patients respectively. MMO was reduced in all patients. The mean MMO (34 mm) reached the level of trismus. The total number of symptoms increased from 3.1 to 6.3 in C-30 and from 3.1 to 8.8 per patient in the H/N35. Severe fatigue, pain, limitations at work, weakness, sad feelings, family problems, sleeping problems, anorexia, financial difficulties, tense/irritable, constipation, nausea, vomiting and depression were most often reported with C-30. Most patients reported poor to moderate quality of life. Severe oral, jaw and neck pain, swallowing problems, taste alterations, sticky saliva, dry mouth, coarseness, dental problems, feeling sick and reduced interest in life/sex were the most common symptoms reported with N/H35. Conclusions: The observed trismus, the 2- to 3-fold increase of symptoms and poorer quality of life highlighted the need for support of oral cancer patients, who receive postoperative radiotherapy or chemoradiotherapy. Reduced systemic health, financial difficulties and family problems could be some of the main reasons for the inadequate compliance of our patients to the study, as shown by others, too. The strength of our study was the homogeneous group of patients: all had oral squamous cell carcinoma and all received post-operative radiotherapy or chemoradiotherapy. The small number of patients represents a weakness.

scholarly journals Impact of Postoperative Radiotherapy and Chemotherapy on Survival for Patients with Node Positive Oral Cancer

2013 ◽  
Vol 04 (11) ◽  
pp. 1-9
Author(s):  
Mohamed Mahmoud ◽  
Tarek Shouman ◽  
Hesham Elhosseny ◽  
Mona Aboelenin ◽  
Mohamed Amin
Keyword(s):  
Oral Cancer ◽  
Postoperative Radiotherapy ◽  
Node Positive

P1.84. Assessing functional outcomes following treatment of oral cancer: Review of literature

2009 ◽  
Vol 3 (1) ◽  
pp. 150
Author(s):  
H. Seikaly ◽  
A.M. Mlynarek ◽  
J. Rieger ◽  
J.R. Harris
Keyword(s):  
Oral Cancer ◽  
Functional Outcomes ◽  
Review Of Literature ◽  
Cancer Review

scholarly journals Trismus and reduced quality of life in patients with oral squamous cell carcinoma, who received post-operative radiotherapy alone or combined with chemotherapy

2017 ◽  
Vol 8 (1) ◽  
pp. 29-36
Author(s):  
Evangelos Galitis ◽  
Vyron Droukas ◽  
Michail Tzakis ◽  
Vassileios Psarras ◽  
Dimitra Galiti ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oral Cancer ◽  
Postoperative Radiotherapy ◽  
Mouth Opening ◽  
Fold Increase ◽  
Sleeping Problems ◽  
Swallowing Problems ◽  
C 30 ◽  
Eortc Qlq

Abstract Background Patients, who receive radiotherapy (RT) for head and neck cancer, develop chronic functional abnormalities and survive with reduced quality of life. Purpose We aimed to study patients with oral cancer, who received post-operative radiotherapy or chemoradiotherapy. Patients Ten patients (mean age 63.8 years) were included. Methods Oral mucositis, pain and xerostomia, maximum mouth opening (MMO) and functional abnormalities before and after RT were recorded. The 35 mm MMO or less was accepted as trismus. Patients completed the EORTC QLQ C-30 and Head/Neck35 questionnaires. Results Mean RT dose was 64.3 Gray. Six patients received chemoradiotherapy. Severe mucositis, pain and xerostomia were recorded in 6 and 5 patients respectively. MMO was reduced in all patients. The mean MMO (34 mm) reached the level of trismus. The total number of symptoms increased from 3.1 to 6.3 in C-30 and from 3.1 to 8.8 per patient in the H/N35. Severe fatigue, pain, limitations at work, weakness, sad feelings, family problems, sleeping problems, anorexia, financial difficulties, tense/irritable, constipation, nausea, vomiting and depression were most often reported with C-30. Most patients reported low to moderate quality of life. Severe oral, jaw and neck pain, swallowing problems, taste alterations, sticky saliva, dry mouth, coarseness, dental problems, feeling sick and reduced interest in life/sex were the most common symptoms reported with N/H35. Conclusions The observed trismus, 2- to 3-fold increase of symptoms and poorer quality of life highlighted the need for support of oral cancer patients, who receive postoperative radiotherapy or chemoradiotherapy.

Effect of postoperative radiotherapy on the functional result of implants placed during ablative surgery for oral cancer

2006 ◽  
Vol 35 (9) ◽  
pp. 803-808 ◽  
Author(s):  
R.H. Schepers ◽  
A.P. Slagter ◽  
J.H.A.M. Kaanders ◽  
F.J.A. van den Hoogen ◽  
M.A.W. Merkx
Keyword(s):  
Oral Cancer ◽  
Functional Result ◽  
Postoperative Radiotherapy ◽  
Ablative Surgery
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