Fatty acid composition of phospholipids in erythrocyte membranes and risk of breast cancer

1990 ◽  
Vol 45 (5) ◽  
pp. 807-810 ◽  
Author(s):  
D. G. Zaridze ◽  
V. E. Chevchenko ◽  
A. A. Levtshuk ◽  
Y. E. Lifanova ◽  
D. M. Maximovitch
2012 ◽  
Vol 141 (2-3) ◽  
pp. 153-161 ◽  
Author(s):  
W.J.M. van der Kemp ◽  
D.W.J. Klomp ◽  
R.S. Kahn ◽  
P.R. Luijten ◽  
H.E. Hulshoff Pol

2018 ◽  
Vol 73 (4) ◽  
pp. 335-343 ◽  
Author(s):  
Yohei Kitamura ◽  
Chieko Kogomori ◽  
Hirokazu  Hamano ◽  
Iwao Maekawa ◽  
Takashi Shimizu ◽  
...  

Background: Term infants can be categorized into 3 sub-groups: early term (37w0d to 38w6d), full term (39w0d to 40w6d), and late term (41w0d and beyond). However, the fatty acid composition among the 3 groups of term infants has not been investigated. The association between fatty acid composition and gestational period of term infants in Japan is unclear. Methods: We assessed the fatty acid composition of maternal erythrocyte membranes in the third trimester and of cord erythrocyte membranes at birth in 212 healthy term Japanese infants using data from a prospective hospital-based cohort study. Results: In maternal erythrocyte membranes, docosahexaenoic acid (DHA) levels and omega-3 index were significantly higher in the late-term group than in the early-term group. In cord erythrocyte membranes, DHA levels were not significantly different between the 3 groups; late-term infants showed significantly higher DHA/arachidonic acid (ARA) and lower 20: 3n-6 and ARA levels compared to early-term infants. Gestational period positively correlated with the DHA status in maternal and cord erythrocyte membranes. Conclusions: Fatty acid composition in maternal and cord erythrocyte membranes varies between early-, full-, and late-term infants, and the greater gestational period may contribute to the relatively high n-3 polyunsaturated fatty acids status in term infants. Furthermore, maternal DHA status in the third semester directly correlates with gestational period in pregnant Japanese women.


1996 ◽  
Vol 126 (12) ◽  
pp. 3109-3117 ◽  
Author(s):  
María C. Rodríguez ◽  
María P. Sáiz ◽  
J. Muntané ◽  
María T. Mitjavila

2011 ◽  
Vol 10 (1) ◽  
pp. 188 ◽  
Author(s):  
Marina Marini ◽  
Provvidenza M Abruzzo ◽  
Alessandra Bolotta ◽  
Arsenio Veicsteinas ◽  
Carla Ferreri

Nutrients ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 1785 ◽  
Author(s):  
Maria Lankinen ◽  
Matti Uusitupa ◽  
Ursula Schwab

The fatty acid compositions of plasma lipids and cell membranes of certain tissues are modified by dietary fatty acid composition. Furthermore, many other factors (age, sex, ethnicity, health status, genes, and gene × diet interactions) affect the fatty acid composition of cell membranes or plasma lipid compartments. Therefore, it is of great importance to understand the complexity of mechanisms that may modify fatty acid compositions of plasma or tissues. We carried out an extensive literature survey of gene × diet interaction in the regulation of fatty acid compositions. Most of the related studies have been observational studies, but there are also a few intervention trials that tend to confirm that true interactions exist. Most of the studies deal with the desaturase enzyme cluster (FADS1, FADS2) in chromosome 11 and elongase enzymes. We expect that new genetic variants are being found that are linked with the genetic regulation of plasma or tissue fatty acid composition. This information is of great help to understanding the contribution of dietary fatty acids and their endogenic metabolism to the development of some chronic diseases.


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