scholarly journals Overexpression of SIX1 is an independent prognostic marker in stage I-III colorectal cancer

2015 ◽  
Vol 137 (9) ◽  
pp. 2104-2113 ◽  
Author(s):  
Christoph Kahlert ◽  
Tristan Lerbs ◽  
Mathieu Pecqueux ◽  
Esther Herpel ◽  
Michael Hoffmeister ◽  
...  
2021 ◽  
Vol Volume 13 ◽  
pp. 1581-1589
Author(s):  
Tong Yu ◽  
Jinglue Song ◽  
Hui Zhou ◽  
Tingyu Wu ◽  
Zhonglin Liang ◽  
...  

2013 ◽  
Vol 108 (2) ◽  
pp. 278-284 ◽  
Author(s):  
R Bertorelle ◽  
M Briarava ◽  
E Rampazzo ◽  
L Biasini ◽  
M Agostini ◽  
...  

2019 ◽  
Vol 8 (4) ◽  
pp. CRC11 ◽  
Author(s):  
Chukwuemeka Ihemelandu ◽  
Aisha Naeem ◽  
Erika Parasido ◽  
Deborah Berry ◽  
Krysta Chaldekas ◽  
...  

Aim: To analyze the clinicopathologic and prognostic significance of Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5), a cancer stem cell marker expression in a cohort of colorectal cancer patients (CRC). Patients & methods: A total of 76 formalin-fixed paraffin-embedded tissue blocks of primary or metastatic tumors from 49 CRC patients were collected for duration 2009–2015. LGR5 expression was assessed through immunohistochemical staining of a tissue microarray. Results: LGR5 was significantly over expressed in CRC tissue samples and found to be a statistically significant independent prognostic marker for an improved overall survival. Conclusion: LGR5 expression was higher in colorectal cancer than in normal tissue. LGR5 was an independent prognostic marker for better clinical outcomes and might be used as a potential therapeutic target in CRCs.


2010 ◽  
Vol 1 (1) ◽  
pp. 73-78 ◽  
Author(s):  
NAOTSUGU SEKO ◽  
NAOHIDE OUE ◽  
TSUYOSHI NOGUCHI ◽  
KAZUHIRO SENTANI ◽  
NAOYA SAKAMOTO ◽  
...  

2015 ◽  
Vol 10 (1) ◽  
Author(s):  
Nathaniel Melling ◽  
Johanna Muth ◽  
Ronald Simon ◽  
Carsten Bokemeyer ◽  
Luigi Terracciano ◽  
...  

2019 ◽  
Vol 8 (5) ◽  
pp. 1699-1708 ◽  
Author(s):  
Kiichi Sugimoto ◽  
Kazuhiro Sakamoto ◽  
Masaya Kawai ◽  
Shingo Kawano ◽  
Shinya Munakata ◽  
...  

Oncotarget ◽  
2015 ◽  
Vol 6 (41) ◽  
pp. 43869-43880 ◽  
Author(s):  
Timo Gemoll ◽  
Sarah Strohkamp ◽  
Katharina Schillo ◽  
Christoph Thorns ◽  
Jens K. Habermann

2011 ◽  
Vol 17 (24) ◽  
pp. 7654-7663 ◽  
Author(s):  
Christoph Kahlert ◽  
Saleh Lahes ◽  
Praveen Radhakrishnan ◽  
Shamik Dutta ◽  
Carolin Mogler ◽  
...  

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