Albumin concentration is a candidate indicator for predicting the risk of calf venous thromboembolism in patients undergoing gynecological surgery

2021 ◽  
Author(s):  
Xing Xin ◽  
Hailong Huang ◽  
Weixin Lu ◽  
Yunli Li ◽  
Fanke Zeng ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
Albumin Concentration ◽  
Gynecological Surgery

scholarly journals American Society of Hematology 2019 guidelines for management of venous thromboembolism: prevention of venous thromboembolism in surgical hospitalized patients

2019 ◽  
Vol 3 (23) ◽  
pp. 3898-3944 ◽  
Author(s):  
David R. Anderson ◽  
Gian Paolo Morgano ◽  
Carole Bennett ◽  
Francesco Dentali ◽  
Charles W. Francis ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
General Surgery ◽  
Major Trauma ◽  
Major Surgery ◽  
Common Source ◽  
Neurosurgical Procedures ◽  
Gynecological Surgery ◽  
Pharmacological Prophylaxis ◽  
American Society ◽  
Major General

AbstractBackground:Venous thromboembolism (VTE) is a common source of perioperative morbidity and mortality.Objective:These evidence-based guidelines from the American Society of Hematology (ASH) intend to support decision making about preventing VTE in patients undergoing surgery.Methods:ASH formed a multidisciplinary guideline panel balanced to minimize bias from conflicts of interest. The McMaster University GRADE Centre supported the guideline-development process, including performing systematic reviews. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach was used to assess evidence and make recommendations, which were subject to public comment.Results:The panel agreed on 30 recommendations, including for major surgery in general (n = 8), orthopedic surgery (n = 7), major general surgery (n = 3), major neurosurgical procedures (n = 2), urological surgery (n = 4), cardiac surgery and major vascular surgery (n = 2), major trauma (n = 2), and major gynecological surgery (n = 2).Conclusions:For patients undergoing major surgery in general, the panel made conditional recommendations for mechanical prophylaxis over no prophylaxis, for pneumatic compression prophylaxis over graduated compression stockings, and against inferior vena cava filters. In patients undergoing total hip or total knee arthroplasty, conditional recommendations included using either aspirin or anticoagulants, as well as for a direct oral anticoagulant over low-molecular-weight heparin (LMWH). For major general surgery, the panel suggested pharmacological prophylaxis over no prophylaxis, using LMWH or unfractionated heparin. For major neurosurgery, transurethral resection of the prostate, or radical prostatectomy, the panel suggested against pharmacological prophylaxis. For major trauma surgery or major gynecological surgery, the panel suggested pharmacological prophylaxis over no prophylaxis.

scholarly journals Serum albumin and risk of venous thromboembolism

2010 ◽  
Vol 104 (07) ◽  
pp. 100-104 ◽  
Author(s):  
Pamela L. Lutsey ◽  
Susan R. Heckbert ◽  
Mary Cushman ◽  
Aaron R. Folsom
Keyword(s):  
Venous Thromboembolism ◽  
Serum Albumin ◽  
Cardiovascular Health ◽  
Hormone Replacement ◽  
Hazard Ratio ◽  
Health Study ◽  
Cardiovascular Health Study ◽  
Albumin Concentration ◽  
Increased Risk ◽  
Low Serum

SummaryThe incidence of venous thromboembolism (VTE) is increased in patients with albuminuria. However, whether a low serum albumin concentration is associated with increased risk of VTE has been a matter of controversy. We determined the association of serum albumin with VTE incidence in two large, prospective, population-based cohorts: the Atherosclerosis Risk in Communities (ARIC) Study (n = 15,300) and the Cardiovascular Health Study (CHS) (n = 5,400). Validated VTE occurrence (n = 462 in ARIC and n = 174 in CHS) was ascertained during follow-up. In both studies, after adjustment for age, sex, race, use of hormone replacement therapy, estimated glomerular filtration rate, history of cancer, and diabetes, serum albumin tended to be associated inversely with VTE. The adjusted hazard ratio per standard deviation lower albumin was 1.18 (95% confidence interval [CI] = 1.08, 1.31) in ARIC and 1.10 (95% CI = 0.94, 1.29) in CHS. The hazard ratio for albumin below (vs. above) the fifth percentile was 1.28 (95% CI = 0.90, 1.84) in ARIC and 1.80 (95% CI = 1.11, 2.93) in CHS. In conclusion, low serum albumin was a modest marker of increased VTE risk. The observed association likely does not reflect cause and effect, but rather that low serum albumin reflects a hyperinflammatory or hypercoagulable state. Whether this association has clinical relevance warrants further study.

scholarly journals Evaluation of Risk Factors for Venous Thromboembolism in Patients Who Underwent Gynecological Surgery and Validation of a Fast-Rating Assessment Table

2019 ◽  
Vol 25 ◽  
pp. 8814-8819
Author(s):  
Ting Yang ◽  
Sijuan Tian ◽  
Yaohui Wang ◽  
Juan Zhao ◽  
Meili Pei ◽  
...  
Keyword(s):  
Risk Factors ◽  
Venous Thromboembolism ◽  
Gynecological Surgery

scholarly journals Predicting of Venous Thromboembolism for Patients Undergoing Gynecological Surgery

Medicine ◽  
2015 ◽  
Vol 94 (39) ◽  
pp. e1653 ◽  
Author(s):  
Hong Qu ◽  
Zhan Li ◽  
Zhenguo Zhai ◽  
Chongdong Liu ◽  
Shuzhen Wang ◽  
...  
Keyword(s):  
Venous Thromboembolism ◽  
Gynecological Surgery

German S3 guideline for the prevention of venous thromboembolism updated Comment on Vasa Supplement 92

VASA ◽  
2016 ◽  
Vol 45 (5) ◽  
pp. 347-348 ◽  
Author(s):  
Sylvia Haas ◽  
Albrecht Encke ◽  
Ina Kopp
Keyword(s):  
Venous Thromboembolism ◽  
S3 Guideline

Venous thromboembolism in a general hospital. An update with low molecular weight heparin prophylaxis

VASA ◽  
2007 ◽  
Vol 36 (1) ◽  
pp. 17-22
Author(s):  
Schulz ◽  
Kesselring ◽  
Seeberger ◽  
Andresen
Keyword(s):  
Molecular Weight ◽  
Pulmonary Embolism ◽  
Venous Thromboembolism ◽  
Low Molecular Weight ◽  
Trauma Patients ◽  
Vte Prophylaxis ◽  
Vein Thrombosis ◽  
Patients At Risk ◽  
Hospital Stays ◽  
Event Rates

Background: Patients admitted to hospital for surgery or acute medical illnesses have a high risk for venous thromboembolism (VTE). Today’s widespread use of low molecular weight heparins (LMWH) for VTE prophylaxis is supposed to have reduced VTE rates substantially. However, data concerning the overall effectiveness of LMWH prophylaxis is sparse. Patients and methods: We prospectively studied all patients with symptomatic and objectively confirmed VTE seen in our hospital over a three year period. Event rates in different wards were analysed and compared. VTE prophylaxis with Enoxaparin was given to all patients at risk during their hospital stay. Results: A total of 50 464 inpatients were treated during the study period. 461 examinations were carried out for symptoms suggestive of VTE and yielded 89 positive results in 85 patients. Seventy eight patients were found to have deep vein thrombosis, 7 had pulmonary embolism, and 4 had both deep venous thrombosis and pulmonary embolism. The overall in hospital VTE event rate was 0.17%. The rate decreased during the study period from 0.22 in year one to 0,16 in year two and 0.13 % in year three. It ranged highest in neurologic and trauma patients (0.32%) and lowest (0.08%) in gynecology-obstetrics. Conclusions: With a simple and strictly applied regimen of prophylaxis with LMWH the overall rate of symptomatic VTE was very low in our hospitalized patients. Beside LMWH prophylaxis, shortening hospital stays and substantial improvements in surgical and anasthesia techniques achieved during the last decades probably play an essential role in decreasing VTE rates.

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