Development of strangulation ileus associated with the ureter of the transplanted kidney 18 years after kidney transplantation

Backgrounds: Kidney transplantation has become a preferred surgical approach for several renal disorders. To acquire required information in basis of acute transplant rejection and its complications, it is important to determine rejection prevalence and its potential causes.Methods: In present retrospective study, during a 37-year survey, 2250 patients received conventional kidney transplantation. The patients who had suffered graft loss, death, and nephrectomy of transplanted kidney during the first month after transplantation enrolled the study and all required data recorded in designed questionnaire. Results: Of 2557 patients underwent kidney transplantation, 86 (3.36%) patients were suffered acute graft loss during the first month after transplantation, that 43 (50%) were males and 43 (50%) were females. Mean age of the patients with acute graft loss was 40.09±14.09. The most common underlying cause for acute graft loss in our study were as follows: acute rejection of transplanted kidney (34.9%), renal vein thrombosis (17.5%), heart infarction (13.9%), idiopathic (6.9%). Of 86 patients, thirty-three patients underwent nephrectomy subsequent to rejection, however, fifty-three patients well responded to medical treatment. In our study the amount of acute nephrectomy during the first month after transplantation was 38.4% (33 patients) which constituted 1.2% of the total graft losses.Conclusion: Renal vein thrombosis is the most common underlying reason for graft loss in kidney transplantation patients, and 1st week of the transplantation is the most probable postoperative time for graft rejection.

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Diagnostic Role of Dopplerography of Renal Vessels in Patients with Late Dysfunction of the Transplanted Kidney

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i44b32667 ◽

2021 ◽

pp. 203-208

Author(s):

Yakymenko Volodymyr Viktorovych

Keyword(s):

Blood Flow ◽

Kidney Transplantation ◽

Renal Transplant ◽

Glomerular Filtration ◽

Non Invasive ◽

Transplanted Kidney ◽

Renal Vessels ◽

Diagnostic Role ◽

Cadaveric Kidney

Aims: Search for non-invasive methods for diagnosing late transplant kidney dysfunction, which can improve control and monitor the condition of the kidney transplant, characterization diagnostic role of dopplerography of renal vessels in patients with late dysfunction of the transplanted kidney. Study design: When conducting dopplerometry, blood flow indices were analyzed from 3 to 6 cycles of heart contractions, followed by an averaged indicator. In addition, the linear blood flow velocity was assessed separately from the renal vein. Place and Duration of Study: For the period 2016-2017 Ultrasound of an allopod was performed in 60 recipients of RT (RENAL TRANSPLANT) in the late postoperative period. Methodology: The average age of the patients was 38.89 ± 1.52 years. There were 34 men (56.6 7%), 26 women (43.33%). All patients were divided into two groups: patients with preserved function and patients with RT (RENAL TRANSPLANT) dysfunction. Related kidney transplantation (RRT) was performed in 55.0% of patients, in 45.0% - cadaveric kidney transplantation (CKP). The groups were comparable in the main clinical and demographic parameters. Results: The reverse dynamics was observed when examining the level of the renal filtration function indicator, the estimated glomerular filtration rate (SKF) - at a TAMX level of more than 15 cm/sec, glomerular filtration was 51.18 ± 1.93 (47.32-55.04) ml/min (p <0.01), and with a decrease in TAMX of less than 15 cm/sec, the level of SKF decreased significantly, more than twice, to the level of 25.40 ± 2.19 (21.02-29.78) ml/min <0.001). Conclusion: The determination of dopplerographic parameters for TP with preserved and especially with impaired depuration function with a direct assessment of TAMX opens up wide opportunities in non-invasive assessment of RT (RENAL TRANSPLANT) changes, identification of developing complications, as well as improved transplant survival.

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Comparison of the Cox Semi-Parametric Model and Parametric Models in Analyzing the Effective Diagnostic Factors in Kidney Transplantation Survival

The Journal of Tolooebehdasht ◽

10.18502/tbj.v17i5.311 ◽

2019 ◽

Author(s):

Mohsen Askarishahi ◽

Abdolamir Atapoor ◽

Roya Hemayati ◽

Shahrzad Shahidi ◽

Sajedeh Zeynali

Keyword(s):

Kidney Transplantation ◽

Kidney Diseases ◽

Survival Rates ◽

Logistic Models ◽

Information Criterion ◽

Parametric Model ◽

Parametric Models ◽

Effective Factors ◽

Transplanted Kidney ◽

Discharge From Hospital

Introduction: Kidney transplantation is the best treatment for patients with advanced kidney diseases. The aim of this study was to determine the rate of transplanted kidney survival and compare the efficiency of Cox semi-parametric model with the parametric models in determination of survival effective factors. Method: This is a historic cohort study including the information of 381 ESRD patients, who underwent kidney transplant surgery from December 2007 to March 2016 in Noor hospital of Isfahan, Iran. In order to identify the effective factors in transplantation survival, the parametric and semi-parametric models were fitted with data and Akaike informationcriterion was used for detecting the most efficient model. Data analysis was carried out with R software, Version 3.1.0 at thesignificance level of 0.05. Results: According to the Kaplan-Mayer method, 1-, 3-, 5-, and 8-year survival rates of transplanted kidney were estimated as 0.987, 0.933, 0.869, and 0.839, respectively. Multi-variable analysis of all fitted models indicated that the duration of dialysis before transplantation (P ≤0.05) and the level of creatinine at the time of discharge from hospital (p≤0.05) had significant relationship with survival of transplanted kidney. Akaike values of Cox, Weibull, exponential, lognormal, and log-logistic models were calculated as 484, 484, 482, 484, and 356, respectively. Conclusion: Based on the Akaike information criterion, the Cox semi-parametric model was selected and proposed as the superior model.

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E107 Effect of amlodipine protecting the transplanted kidney on hypertension after kidney transplantation

American Journal of Hypertension ◽

10.1016/s0895-7061(97)91169-9 ◽

1998 ◽

Vol 11 (4) ◽

pp. 122A

Author(s):

T SHUDE

Keyword(s):

Kidney Transplantation ◽

Transplanted Kidney

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The stiffness of transplanted kidneys changes with time after renal transplantation

Acta Radiologica ◽

10.1177/02841851211030770 ◽

2021 ◽

pp. 028418512110307

Author(s):

Shaona Chen ◽

Jin Li ◽

Bidan Zeng ◽

Zhimin Zhu ◽

Yanhua Luo ◽

...

Keyword(s):

Renal Function ◽

Kidney Transplantation ◽

Renal Transplantation ◽

Kidney Disease ◽

The United States ◽

Renal Transplant Recipients ◽

Scientific Review ◽

Transplanted Kidney ◽

Stable Renal Function ◽

Transplanted Kidneys

Background Kidney transplantation is one of the most effective ways to treat end-stage kidney disease. However, 5000 renal transplant recipients start or restart dialysis because of chronic allograft nephropathy (CAN) every year in the United States. Detecting changes in the stiffness of transplanted kidneys can help diagnose transplanted kidney disease. Purpose To explore changes in the stiffness of transplanted kidneys after renal transplantation using shear wave elastography (SWE). Material and Methods This study conducted consecutive follow-up observations on 10 patients after kidney transplantation. SWE examination was performed in the first week, second week, first month, second month, third month, fourth month, fifth month, and sixth month after surgery. This study also analyzed the graft stiffness of 86 patients with stable renal function recovery one month after surgery. Results The results show that there is a change in the stiffness of the transplanted kidney over time after renal transplantation. It decreases rapidly within one month after renal transplantation and tends to be stable after one month. The mean renal cortical and pyramidal stiffness of patients with stable renal function were 28.48 ± 4.27 kPa and 21.97 ± 3.90 kPa, respectively. Conclusion Consecutive stiffness measurement of transplanted kidneys is an effective method for monitoring the function of transplanted kidneys. According to the change in transplanted kidney stiffness, we can designate a more scientific review plan to determine the functional status of the transplanted kidney.

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Analysis of complications after living-related kidney transplantation: a single-center experience

Transplantologiya The Russian Journal of Transplantation ◽

10.23873/2074-0506-2021-13-1-63-73 ◽

2021 ◽

Vol 13 (1) ◽

pp. 63-73

Author(s):

F. A. Khadjibaev ◽

V. Kh. Sharipova ◽

P. K. Sultanov

Keyword(s):

Kidney Transplantation ◽

Postoperative Complications ◽

Renal Transplant ◽

Graft Rejection ◽

Hypovolemic Shock ◽

Diagnosis And Treatment ◽

Research Centre ◽

Main Role ◽

Renal Graft ◽

Transplanted Kidney

Background. The one-year renal graft survival rates have grown to 93.4% for transplantation from cadaveric and 97.2% from living donors. Early detection and elimination of complications after kidney transplantation improve these figures.The study purpose was to develop an algorithm for the diagnosis and treatment tactics of postoperative complications after kidney transplantation by reviewing literature data and analyzing the results of our own experience.Material and methods. The study included 75 patients who underwent kidney transplantation from a living donor at the Republican Research Centre of Emergency Medicine from March 2018 to December 2019.Results. The original authors' algorithm developed for the diagnosis and treatment of complications after kidney transplantation covers all postoperative complications that lead to renal transplant dysfunction. It is based on assessing the symptoms that typically occur in a specific complication. The main instrumental methods in the diagnosis of postoperative complications are ultrasound and radiological investigational techniques. The biopsy has the main role in diagnosing a graft rejection. Among 75 patients after kidney transplantation, 23 (30.6%) developed various early postoperative complications, including both surgical and immunological ones. Renal graft dysfunction was eliminated in 17 (73.9%) of 23 patients. The loss of a transplanted kidney was associated with the death of 7 recipients (9.3%). The causes of death were pulmonary embolism in 2 (2.7%) cases, infection and sepsis as a result of immunosuppression in 2 (2.7%) cases, hypovolemic shock in 2 (2.7%) cases, and acute ischemic stroke in 1 (1.3%) case. Two recipients underwent renal transplant nephrectomy. The cause of nephrectomy was graft rejection and bleeding from the renal artery. A oneyear survival rate was 90.7%. The proposed treatment and diagnostic algorithm showed a 95.7% diagnostic value in identifying the complications, and 91.3% of the therapeutic effect in coping with a renal transplant dysfunction.Conclusions. Early treatment of revealed complications allows saving the transplanted kidney function. Step-bystep differential diagnosis of complications after kidney transplantation, according to the proposed algorithm, allows choosing the treatment tactics based on complication pathogenesis.

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