Cell-free synthesis of Schistosoma mansoni surface antigens: stage specificity of their expression.

1984 ◽  
Vol 3 (1) ◽  
pp. 213-219 ◽  
Author(s):  
M. Knight ◽  
A.J. Simpson ◽  
G. Payares ◽  
M. Chaudri ◽  
S.R. Smithers
Keyword(s):  
Schistosoma Mansoni ◽  
Surface Antigens ◽  
Stage Specificity

Vaccination against Schistosoma mansoni with purified surface antigens

Science ◽  
1985 ◽  
Vol 227 (4686) ◽  
pp. 535-538 ◽  
Author(s):  
M. Smith ◽  
J. Clegg
Keyword(s):  
Schistosoma Mansoni ◽  
Surface Antigens

Biochemical studies on the 30–40 kDa Schistosoma mansoni surface antigens

1985 ◽  
Vol 16 (3) ◽  
pp. 277-288 ◽  
Author(s):  
Colette Dissous ◽  
Jean-Marie Grzych ◽  
André Capron
Keyword(s):  
Schistosoma Mansoni ◽  
Surface Antigens ◽  
Biochemical Studies

Isolation and Characterization of Surface Antigens from Schistosoma mansoni. II Antigenicity of Radiolabeled Proteins from Adult Worms

1979 ◽  
Vol 65 (4) ◽  
pp. 497 ◽  
Author(s):  
Eugene G. Hayunga ◽  
K. Darwin Murrell ◽  
David W. Taylor ◽  
Wilton E. Vannier
Keyword(s):  
Schistosoma Mansoni ◽  
Surface Antigens ◽  
Isolation And Characterization

scholarly journals Genetic Analysis of Adult-Specific Surface Antigenic Differences Between Varieties of the Nematode Caenorhabditis elegans

Genetics ◽  
1987 ◽  
Vol 117 (3) ◽  
pp. 467-476
Author(s):  
Samuel M Politz ◽  
Karl J Chin ◽  
Daniel L Herman
Keyword(s):  
Caenorhabditis Elegans ◽  
Linkage Group ◽  
Genetic Analysis ◽  
Surface Antigen ◽  
Single Gene ◽  
Surface Antigens ◽  
Nematode Caenorhabditis Elegans ◽  
Specific Antibodies ◽  
C Elegans ◽  
Stage Specificity

ABSTRACT We have studied developmental stage-specificity and genetic specification of surface antigens in the nematode Caenorhabditis elegans. Rabbit antisera directed against the adult C. elegans cuticle were used in conjunction with antiserum adsorption experiments to obtain antibody reagents with specificity for the adult surface. Adult-specific antibodies were used to identify several varietal strains of C. elegans that display antigen-negative phenotypes as adults. Genetic mapping results using the surface antigen phenotype as a marker indicated that a single gene (designated srf-1) or cluster of genes on linkage group II determines the adult surface antigen phenotype.

Temporal differences in praziquantel- and oxamniquine-induced tegumental damage to adult Schistosoma mansoni: implications for drug-antibody synergy

Parasitology ◽  
1996 ◽  
Vol 112 (1) ◽  
pp. 47-58 ◽  
Author(s):  
P. G. Fallon ◽  
R. E. Fookes ◽  
G. A. Wharton
Keyword(s):  
Drug Treatment ◽  
Schistosoma Mansoni ◽  
Adult Worm ◽  
Surface Antigens ◽  
Drug Induced ◽  
Temporal Differences ◽  
Temporal Study ◽  
Praziquantel Treatment

SUMMARYA temporal study of the effects on the tegument of Schistosoma mansoni adult worm following in vivo praziquantel and oxamniquine treatment was performed. Drug-induced damage to the tegument, exposure of surface antigens and attachment of host antibody occurred rapidly, within 1 h, following praziquantel treatment. Oxamniquine-treated worms required 4–8 days for these effects to be apparent. The 2 drugs differed in the degree and sites of damage on the worm surface. The administration of 2 different polyspecific rabbit sera with drug significantly increased the efficacy of praziquantel when administered with the drug, but not when given 6–9 days after drug treatment. In contrast, only 1 serum was synergistic with oxamniquine when administered with drug and both sera were synergistic when given 6–9 days after drug treatment. The effect of immune killing of drug-treated worms is discussed.

Schistosoma mansoni: Antigen preparations which induce antibodies to schistosomula surface antigens

1985 ◽  
Vol 60 (3) ◽  
pp. 294-303 ◽  
Author(s):  
F. Hackett ◽  
A.J.G. Simpson ◽  
M. Knight ◽  
P. Ali ◽  
G. Payares ◽  
...  
Keyword(s):  
Schistosoma Mansoni ◽  
Surface Antigens
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